PDB entry 1t39
View 1t39 on RCSB PDB site
Description: human o6-alkylguanine-DNA alkyltransferase covalently crosslinked to DNA
Class: transferase/DNA
Keywords: alkyltransferase, methyltransferase, DNA repair, helix-turn-helix, transferase/DNA complex
Deposited on
2004-04-25, released
2004-07-13
The last revision prior to the SCOPe 2.08 freeze date was dated
2009-02-24, with a file datestamp of
2009-02-03.
Experiment type: XRAY
Resolution: 3.3 Å
R-factor: 0.296
AEROSPACI score: 0.08
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: methylated-DNA--protein-cysteine methyltransferase
Species: Homo sapiens [TaxId:9606]
Gene: MGMT
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d1t39a1, d1t39a2 - Chain 'B':
Compound: methylated-DNA--protein-cysteine methyltransferase
Species: Homo sapiens [TaxId:9606]
Gene: MGMT
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d1t39b1, d1t39b2 - Chain 'C':
Compound: 5'-d(*gp*cp*cp*ap*tp*gp*(e1x)p*cp*tp*ap*gp*tp*a)-3'
- Chain 'D':
Compound: 5'-d(*tp*ap*cp*tp*ap*gp*cp*cp*ap*tp*gp*gp*c)-3'
- Chain 'E':
Compound: 5'-d(*gp*cp*cp*ap*tp*gp*(e1x)p*cp*tp*ap*gp*tp*a)-3'
- Chain 'F':
Compound: 5'-d(*tp*ap*cp*tp*ap*gp*cp*cp*ap*tp*gp*gp*c)-3'
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>1t39A (A:)
mrgshhhhhhgsmdkdcemkrttldsplgklelsgceqglheikllgkgtsaadavevpa
paavlggpeplmqctawlnayfhqpeaieefpvpalhhpvfqqesftrqvlwkllkvvkf
gevisyqqlaalagnpkaaravggamrgnpvpilipchrvvcssgavgnysgglavkewl
laheghrl
Sequence, based on observed residues (ATOM records): (download)
>1t39A (A:)
cemkrttldsplgklelsgceqglheikllgpeplmqctawlnayfhqpeaieefpvpal
hhpvfqqesftrqvlwkllkvvkfgevisyqqlaalagnpkaaravggamrgnpvpilip
chrvvcssgavgnysgglavkewllaheghr
- Chain 'B':
Sequence, based on SEQRES records: (download)
>1t39B (B:)
mrgshhhhhhgsmdkdcemkrttldsplgklelsgceqglheikllgkgtsaadavevpa
paavlggpeplmqctawlnayfhqpeaieefpvpalhhpvfqqesftrqvlwkllkvvkf
gevisyqqlaalagnpkaaravggamrgnpvpilipchrvvcssgavgnysgglavkewl
laheghrl
Sequence, based on observed residues (ATOM records): (download)
>1t39B (B:)
mkrttldsplgklelsgceqglheikllgpeplmqctawlnayfhqpeaieefpvpalhh
pvfqqesftrqvlwkllkvvkfgevisyqqlaalagnpkaaravggamrgnpvpilipch
rvvcssgavgnysgglavkewllahegh
- Chain 'C':
No sequence available.
- Chain 'D':
No sequence available.
- Chain 'E':
No sequence available.
- Chain 'F':
No sequence available.