SCOPe 2.08: Structural Classification of Proteins

PDB entry 1t36

View 1t36 on RCSB PDB site
Description: Crystal structure of E. coli carbamoyl phosphate synthetase small subunit mutant C248D complexed with uridine 5'-monophosphate
Class: ligase
Keywords: channeling, pyrimidine biosynthesis, arginine biosynthesis, LIGASE
Deposited on 2004-04-24, released 2004-09-21
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-25.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: 0.179
AEROSPACI score: 0.41 (click here for full SPACI score report)

Chains and heterogens:

Chain 'A':
Compound: Carbamoyl-phosphate synthase large chain
Species: Escherichia coli [TaxId:562]
Gene: CARB, PYRA, B0033
Database cross-references and differences (RAF-indexed):
- Uniprot P00968 (0-1072)
Domains in SCOPe 2.08: d1t36a1, d1t36a2, d1t36a3, d1t36a4, d1t36a5, d1t36a6
Chain 'B':
Compound: Carbamoyl-phosphate synthase small chain
Species: Escherichia coli [TaxId:562]
Gene: CARA, PYRA, B0032, Z0037, ECS0035
Database cross-references and differences (RAF-indexed):
- Uniprot P00907
  - engineered (247)
Domains in SCOPe 2.08: d1t36b1, d1t36b2
Chain 'C':
Compound: Carbamoyl-phosphate synthase large chain
Species: Escherichia coli [TaxId:562]
Gene: CARB, PYRA, B0033
Database cross-references and differences (RAF-indexed):
- Uniprot P00968 (0-1072)
Domains in SCOPe 2.08: d1t36c1, d1t36c2, d1t36c3, d1t36c4, d1t36c5, d1t36c6
Chain 'D':
Compound: Carbamoyl-phosphate synthase small chain
Species: Escherichia coli [TaxId:562]
Gene: CARA, PYRA, B0032, Z0037, ECS0035
Database cross-references and differences (RAF-indexed):
- Uniprot P00907
  - engineered (247)
Domains in SCOPe 2.08: d1t36d1, d1t36d2
Chain 'E':
Compound: Carbamoyl-phosphate synthase large chain
Species: Escherichia coli [TaxId:562]
Gene: CARB, PYRA, B0033
Database cross-references and differences (RAF-indexed):
- Uniprot P00968 (0-1072)
Domains in SCOPe 2.08: d1t36e1, d1t36e2, d1t36e3, d1t36e4, d1t36e5, d1t36e6
Chain 'F':
Compound: Carbamoyl-phosphate synthase small chain
Species: Escherichia coli [TaxId:562]
Gene: CARA, PYRA, B0032, Z0037, ECS0035
Database cross-references and differences (RAF-indexed):
- Uniprot P00907
  - engineered (247)
Domains in SCOPe 2.08: d1t36f1, d1t36f2
Chain 'G':
Compound: Carbamoyl-phosphate synthase large chain
Species: Escherichia coli [TaxId:562]
Gene: CARB, PYRA, B0033
Database cross-references and differences (RAF-indexed):
- Uniprot P00968 (0-1072)
Domains in SCOPe 2.08: d1t36g1, d1t36g2, d1t36g3, d1t36g4, d1t36g5, d1t36g6
Chain 'H':
Compound: Carbamoyl-phosphate synthase small chain
Species: Escherichia coli [TaxId:562]
Gene: CARA, PYRA, B0032, Z0037, ECS0035
Database cross-references and differences (RAF-indexed):
- Uniprot P00907
  - engineered (247)
Domains in SCOPe 2.08: d1t36h1, d1t36h2
Heterogens: MN, K, PO4, CL, ADP, ORN, NET, U, HOH

PDB Chain Sequences:

Chain 'A':
Sequence, based on SEQRES records: (download)

>1t36A (A:)
mpkrtdiksililgagpivigqacefdysgaqackalreegyrvilvnsnpatimtdpem
adatyiepihwevvrkiiekerpdavlptmggqtalncalelerqgvleefgvtmigata
daidkaedrrrfdvamkkigletarsgiahtmeealavaadvgfpciirpsftmggsggg
iaynreefeeicargldlsptkellidesligwkeyemevvrdkndnciivcsienfdam
gihtgdsitvapaqtltdkeyqimrnasmavlreigvetggsnvqfavnpkngrliviem
nprvsrssalaskatgfpiakvaaklavgytldelmnditggrtpasfepsidyvvtkip
rfnfekfagandrlttqmksvgevmaigrtqqeslqkalrglevgatgfdpkvslddpea
ltkirrelkdagadriwyiadafraglsvdgvfnltnidrwflvqieelvrleekvaevg
itglnadflrqlkrkgfadarlaklagvreaeirklrdqydlhpvykrvdtcaaefatdt
aymystyeeeceanpstdrekimvlgggpnrigqgiefdyccvhaslalredgyetimvn
cnpetvstdydtsdrlyfepvtledvleivriekpkgvivqyggqtplklaraleaagvp
vigtspdaidraedrerfqhaverlklkqpanatvtaiemavekakeigyplvvrpsyvl
ggrameivydeadlrryfqtavsvsndapvlldhflddavevdvdaicdgemvliggime
hieqagvhsgdsacslpaytlsqeiqdvmrqqvqklafelqvrglmnvqfavknnevyli
evnpraartvpfvskatgvplakvaarvmagkslaeqgvtkevippyysvkevvlpfnkf
pgvdpllgpemrstgevmgvgrtfaeafakaqlgsnstmkkhgrallsvregdkervvdl
aakllkqgfeldathgtaivlgeaginprlvnkvhegrphiqdrikngeytyiinttsgr
raiedsrvirrsalqykvhydttlnggfatamalnadatekvisvqemhaqik