PDB entry 1t21

View 1t21 on RCSB PDB site
Description: Structural basis for degenerate recognition of HIV peptide variants by cytotoxic lymphocyte, variant SL9, monoclinic crystal
Class: immune system
Keywords: ctl, cytotoxic t lymphocytes, hiv, human immunodeficiency virus, MHC, major histocompatibility complex, pmhc, peptide MHC complex, rmsd, root-mean-squared deviation, siv, simian immunodeficiency virus, tcr, T-cell receptor
Deposited on 2004-04-19, released 2005-09-06
The last revision prior to the SCOP 1.75 freeze date was dated 2006-08-01, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 2.19 Å
R-factor: 0.177
AEROSPACI score: 0.52 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: HLA class I histocompatibility antigen, A-2 alpha chain
    Species: HOMO SAPIENS
    Gene: HLA-A, HLAA
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1t21a1, d1t21a2
  • Chain 'B':
    Compound: Beta-2-microglobulin
    Species: HOMO SAPIENS
    Gene: B2M
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1t21b1
  • Chain 'C':
    Compound: gag peptide
    Species: synthetic, synthetic
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1t21A (A:)
gshsmryfftsvsrpgrgeprfiavgyvddtqfvrfdsdaasqrmeprapwieqegpeyw
dgetrkvkahsqthrvdlgtlrgyynqseagshtvqrmygcdvgsdwrflrgyhqyaydg
kdyialkedlrswtaadmaaqttkhkweaahvaeqlraylegtcvewlrrylengketlq
rtdapkthmthhavsdheatlrcwalsfypaeitltwqrdgedqtqdtelvetrpagdgt
fqkwaavvvpsgqeqrytchvqheglpkpltlrwe

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1t21B (B:)
iqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskdw
sfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm

  • Chain 'C':
    No sequence available.