PDB entry 1t09
View 1t09 on RCSB PDB site
Description: Crystal structure of human cytosolic NADP(+)-dependent isocitrate dehydrogenase in complex NADP
Class: Oxidoreductase
Keywords: Rossmann fold, protein-cofactor complex, NADP, Oxidoreductase
Deposited on
2004-04-08, released
2004-06-15
The last revision prior to the SCOPe 2.06 freeze date was dated
2009-02-24, with a file datestamp of
2009-03-01.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: 0.21
AEROSPACI score: 0.27
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: isocitrate dehydrogenase [nadp] cytoplasmic
Species: Homo sapiens [TaxId:9606]
Gene: IDH
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.06: d1t09a_ - Chain 'B':
Compound: isocitrate dehydrogenase [nadp] cytoplasmic
Species: Homo sapiens [TaxId:9606]
Gene: IDH
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.06: d1t09b_ - Heterogens: NAP, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence; same for both SEQRES and ATOM records: (download)
>1t09A (A:)
mskkisggsvvemqgdemtriiwelikeklifpyveldlhsydlgienrdatndqvtkda
aeaikkhnvgvkcatitpdekrveefklkqmwkspngtirnilggtvfreaiickniprl
vsgwvkpiiigrhaygdqyratdfvvpgpgkveitytpsdgtqkvtylvhnfeegggvam
gmynqdksiedfahssfqmalskgwplylstkntilkkydgrfkdifqeiydkqyksqfe
aqkiwyehrliddmvaqamkseggfiwacknydgdvqsdsvaqgygslgmmtsvlvcpdg
ktveaeaahgtvtrhyrmyqkgqetstnpiasifawtrglahrakldnnkelaffanale
evsietieagfmtkdlaacikglpnvqrsdylntfefmdklgenlkiklaqakl
- Chain 'B':
Sequence; same for both SEQRES and ATOM records: (download)
>1t09B (B:)
mskkisggsvvemqgdemtriiwelikeklifpyveldlhsydlgienrdatndqvtkda
aeaikkhnvgvkcatitpdekrveefklkqmwkspngtirnilggtvfreaiickniprl
vsgwvkpiiigrhaygdqyratdfvvpgpgkveitytpsdgtqkvtylvhnfeegggvam
gmynqdksiedfahssfqmalskgwplylstkntilkkydgrfkdifqeiydkqyksqfe
aqkiwyehrliddmvaqamkseggfiwacknydgdvqsdsvaqgygslgmmtsvlvcpdg
ktveaeaahgtvtrhyrmyqkgqetstnpiasifawtrglahrakldnnkelaffanale
evsietieagfmtkdlaacikglpnvqrsdylntfefmdklgenlkiklaqakl