PDB entry 1t04

View 1t04 on RCSB PDB site
Description: Three dimensional structure of a humanized anti-IFN-Gamma Fab in C2 space group
Class: immune system
Keywords: Antibody Engineering, Humanized and Chimeric Antibody, FAB, X-ray Structure, three-dimensional structure, Gamma-interferon, Immune System
Deposited on 2004-04-07, released 2004-10-05
The last revision prior to the SCOPe 2.05 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 3 Å
R-factor: 0.217
AEROSPACI score: 0.21 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Huzaf Antibody Light Chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d1t04a1, d1t04a2
  • Chain 'B':
    Compound: Huzaf Antibody Heavy Chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 1T04 (0-218)
    Domains in SCOPe 2.05: d1t04b1, d1t04b2
  • Chain 'C':
    Compound: Huzaf Antibody Light Chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d1t04c1, d1t04c2
  • Chain 'D':
    Compound: Huzaf Antibody Heavy Chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 1T04 (0-218)
    Domains in SCOPe 2.05: d1t04d1, d1t04d2
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1t04A (A:)
    diqmtqspstlsasvgdrvtitckasenvdtyvswyqqkpgkapklliygasnrytgvps
    rfsgsgsgtdftltisslqpddfatyycgqsynypftfgqgtkvevkrtvaapsvfifpp
    sdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstlt
    lskadyekhkvyacevthqglsspvtksfnrgec
    

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1t04B (B:)
    evqlvqsgaelkkpgssvkvsckasgyiftsswinwvkqapgqglewigridpsdgevhy
    nqdfkdkatltvdkstntaymelsslrsedtavyycargflpwfadwgqgtlvtvssast
    kgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssgly
    slssvvtvpssslgtqtyicnvnhkpsntkvdkkvepks
    

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1t04C (C:)
    diqmtqspstlsasvgdrvtitckasenvdtyvswyqqkpgkapklliygasnrytgvps
    rfsgsgsgtdftltisslqpddfatyycgqsynypftfgqgtkvevkrtvaapsvfifpp
    sdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstlt
    lskadyekhkvyacevthqglsspvtksfnrgec
    

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1t04D (D:)
    evqlvqsgaelkkpgssvkvsckasgyiftsswinwvkqapgqglewigridpsdgevhy
    nqdfkdkatltvdkstntaymelsslrsedtavyycargflpwfadwgqgtlvtvssast
    kgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssgly
    slssvvtvpssslgtqtyicnvnhkpsntkvdkkvepks