PDB entry 1syq

View 1syq on RCSB PDB site
Description: Human vinculin head domain VH1, residues 1-258, in complex with human talin's vinculin binding site 1, residues 607-636
Class: cell adhesion
Keywords: cytoskeleton, vinculin, talin, CELL ADHESION
Deposited on 2004-04-01, released 2004-07-20
The last revision prior to the SCOPe 2.07 freeze date was dated 2010-06-09, with a file datestamp of 2010-06-04.
Experiment type: XRAY
Resolution: 2.42 Å
R-factor: 0.188
AEROSPACI score: 0.36 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: vinculin isoform VCL
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P18206 (6-263)
      • expression tag (5)
    Domains in SCOPe 2.07: d1syqa1, d1syqa2, d1syqa3
  • Chain 'B':
    Compound: Talin 1
    Database cross-references and differences (RAF-indexed):
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1syqA (A:)
hhhhhhmpvfhtrtiesilepvaqqishlvimheegevdgkaipdltapvaavqaavsnl
vrvgketvqttedqilkrdmppafikvenactklvqaaqmlqsdpysvpardylidgsrg
ilsgtsdllltfdeaevrkiirvckgileyltvaevvetmedlvtytknlgpgmtkmakm
iderqqelthqehrvmlvnsmntvkellpvlisamkifvttknsknqgieealknrnftv
ekmsaeineiirvlqltswdedaw

    Sequence, based on observed residues (ATOM records): (download) 
    >1syqA (A:)
hmpvfhtrtiesilepvaqqishlvimheegevdgkaipdltapvaavqaavsnlvrvgk
etvqttedqilkrdmppafikvenactklvqaaqmlqsdpysvpardylidgsrgilsgt
sdllltfdeaevrkiirvckgileyltvaevvetmedlvtytknlgpgmtkmakmiderq
qelthqehrvmlvnsmntvkellpvlisamkifvttknsknqgieealknrnftvekmsa
eineiirvlqltswdedaw

  • Chain 'B':
    No sequence available.