PDB entry 1sw3

View 1sw3 on RCSB PDB site
Description: Triosephosphate isomerase from Gallus gallus, loop 6 mutant T175V
Class: isomerase
Keywords: TIM barrel, flexible loop, hinge, ISOMERASE
Deposited on 2004-03-30, released 2004-08-24
The last revision prior to the SCOPe 2.01 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.03 Å
R-factor: 0.145
AEROSPACI score: 0.49 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: triosephosphate isomerase
    Species: Gallus gallus [TaxId:9031]
    Gene: TPI1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00940 (Start-247)
      • engineered (174)
    Domains in SCOPe 2.01: d1sw3a_
  • Chain 'B':
    Compound: triosephosphate isomerase
    Species: Gallus gallus [TaxId:9031]
    Gene: TPI1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00940 (Start-247)
      • engineered (174)
    Domains in SCOPe 2.01: d1sw3b_
  • Heterogens: PGA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >1sw3A (A:)
    maprkffvggnwkmngdkkslgelihtlngaklsadtevvcgapsiyldfarqkldakig
    vaaqncykvpkgaftgeispamikdigaawvilghserrhvfgesdeligqkvahalaeg
    lgviacigekldereagitekvvfeqtkaiadnvkdwskvvlayepvwaigtgkvatpqq
    aqevheklrgwlkshvsdavaqstriiyggsvtggnckelasqhdvdgflvggaslkpef
    vdiinakh
    

    Sequence, based on observed residues (ATOM records): (download)
    >1sw3A (A:)
    aprkffvggnwkmngdkkslgelihtlngaklsadtevvcgapsiyldfarqkldakigv
    aaqncykvpkgaftgeispamikdigaawvilghserrhvfgesdeligqkvahalaegl
    gviacigekldereagitekvvfeqtkaiadnvkdwskvvlayepvwaigtgkvatpqqa
    qevheklrgwlkshvsdavaqstriiyggsvtggnckelasqhdvdgflvggaslkpefv
    diinakh
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >1sw3B (B:)
    maprkffvggnwkmngdkkslgelihtlngaklsadtevvcgapsiyldfarqkldakig
    vaaqncykvpkgaftgeispamikdigaawvilghserrhvfgesdeligqkvahalaeg
    lgviacigekldereagitekvvfeqtkaiadnvkdwskvvlayepvwaigtgkvatpqq
    aqevheklrgwlkshvsdavaqstriiyggsvtggnckelasqhdvdgflvggaslkpef
    vdiinakh
    

    Sequence, based on observed residues (ATOM records): (download)
    >1sw3B (B:)
    aprkffvggnwkmngdkkslgelihtlngaklsadtevvcgapsiyldfarqkldakigv
    aaqncykvpkgaftgeispamikdigaawvilghserrhvfgesdeligqkvahalaegl
    gviacigekldereagitekvvfeqtkaiadnvkdwskvvlayepvwaigtgkvatpqqa
    qevheklrgwlkshvsdavaqstriiyggsvtggnckelasqhdvdgflvggaslkpefv
    diinakh