PDB entry 1sr9

View 1sr9 on RCSB PDB site
Description: Crystal Structure of LeuA from Mycobacterium tuberculosis
Class: transferase
Keywords: TIM barrel
Deposited on 2004-03-22, released 2004-05-18
The last revision prior to the SCOP 1.75 freeze date was dated 2004-06-22, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.17
AEROSPACI score: 0.54 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 2-isopropylmalate synthase
    Species: Mycobacterium tuberculosis
    Database cross-references and differences (RAF-indexed):
    • Uniprot P96420
      • modified residue (40)
      • modified residue (89)
      • modified residue (97)
      • modified residue (104)
      • modified residue (256)
      • modified residue (269)
      • modified residue (389)
      • modified residue (403)
      • modified residue (440)
      • modified residue (479)
      • modified residue (558)
    Domains in SCOP 1.75: d1sr9a1, d1sr9a2, d1sr9a3
  • Chain 'B':
    Compound: 2-isopropylmalate synthase
    Species: Mycobacterium tuberculosis
    Database cross-references and differences (RAF-indexed):
    • Uniprot P96420
      • modified residue (40)
      • modified residue (89)
      • modified residue (97)
      • modified residue (104)
      • modified residue (256)
      • modified residue (269)
      • modified residue (389)
      • modified residue (403)
      • modified residue (440)
      • modified residue (479)
      • modified residue (558)
    Domains in SCOP 1.75: d1sr9b1, d1sr9b2, d1sr9b3
  • Heterogens: ZN, CL, KIV, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1sr9A (A:)
mttsespdaytesfgahtivkpagpprvgqpswnpqrassmpvnryrpfaeevepirlrn
rtwpdrvidraplwcavdlrdgnqalidpmsparkrrmfdllvrmgykeievgfpsasqt
dfdfvreiieqgaipddvtiqvltqcrpeliertfqacsgapraivhfynstsilqrrvv
franraevqaiatdgarkcveqaakypgtqwrfeyspesytgteleyakqvcdavgevia
ptperpiifnlpatvemttpnvyadsiewmsrnlanresvilslhphndrgtavaaaelg
faagadriegclfgngertgnvclvtlglnlfsrgvdpqidfsnideirrtveycnqlpv
herhpyggdlvytafsgshqdainkgldamkldadaadcdvddmlwqvpylpidprdvgr
tyeavirvnsqsgkggvayimktdhglslprrlqiefsqviqkiaegtageggevspkem
wdafaeeylapvrplerirqhvdaadddggttsitatvkingveteisgsgngplaafvh
aladvgfdvavldyyehamsagddaqaaayveasvtiaspaqpgeagrhasdpvtiaspa
qpgeagrhasdpvtsktvwgvgiapsittaslravvsavnraar

    Sequence, based on observed residues (ATOM records): (download) 
    >1sr9A (A:)
tivkpagpprvgqpswnpqrassmpvnryrpfaeevepirlrnrtwpdrvidraplwcav
dlrdgnqalidpmsparkrrmfdllvrmgykeievgfpsasqtdfdfvreiieqgaipdd
vtiqvltqcrpeliertfqacsgapraivhfynstsilqrrvvfranraevqaiatdgar
kcveqaakypgtqwrfeyspesytgteleyakqvcdavgeviaptperpiifnlpatvem
ttpnvyadsiewmsrnlanresvilslhphndrgtavaaaelgfaagadriegclfgnge
rtgnvclvtlglnlfsrgvdpqidfsnideirrtveycnqlpvherhpyggdlvytafsg
shqdainkgldamkldadaadcdvddmlwqvpylpidprdvgrtyeavikggvayimktd
hglslprrlqiefsqviqkievspkemwdafaeeylapvrplerirqhvdaadddggtts
itatvkingveteisgsgngplaafvhaladvgfdvavldyyehamsagddaqaaayvea
svtisktvwgvgiapsittaslravvsavnraa

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1sr9B (B:)
mttsespdaytesfgahtivkpagpprvgqpswnpqrassmpvnryrpfaeevepirlrn
rtwpdrvidraplwcavdlrdgnqalidpmsparkrrmfdllvrmgykeievgfpsasqt
dfdfvreiieqgaipddvtiqvltqcrpeliertfqacsgapraivhfynstsilqrrvv
franraevqaiatdgarkcveqaakypgtqwrfeyspesytgteleyakqvcdavgevia
ptperpiifnlpatvemttpnvyadsiewmsrnlanresvilslhphndrgtavaaaelg
faagadriegclfgngertgnvclvtlglnlfsrgvdpqidfsnideirrtveycnqlpv
herhpyggdlvytafsgshqdainkgldamkldadaadcdvddmlwqvpylpidprdvgr
tyeavirvnsqsgkggvayimktdhglslprrlqiefsqviqkiaegtageggevspkem
wdafaeeylapvrplerirqhvdaadddggttsitatvkingveteisgsgngplaafvh
aladvgfdvavldyyehamsagddaqaaayveasvtiaspaqpgeagrhasdpvtiaspa
qpgeagrhasdpvtsktvwgvgiapsittaslravvsavnraar

    Sequence, based on observed residues (ATOM records): (download) 
    >1sr9B (B:)
tivkpagpprvgqpswnpqrassmpvnryrpfaeevepirlrnrtwpdrvidraplwcav
dlrdgnqalidpmsparkrrmfdllvrmgykeievgfpsasqtdfdfvreiieqgaipdd
vtiqvltqcrpeliertfqacsgapraivhfynstsilqrrvvfranraevqaiatdgar
kcveqaakypgtqwrfeyspesytgteleyakqvcdavgeviaptperpiifnlpatvem
ttpnvyadsiewmsrnlanresvilslhphndrgtavaaaelgfaagadriegclfgnge
rtgnvclvtlglnlfsrgvdpqidfsnideirrtveycnqlpvherhpyggdlvytafsg
shqdainkgldamkldadaadcdvddmlwqvpylpidprdvgrtyeavirvnkggvayim
ktdhglslprrlqiefsqviqkvspkemwdafaeeylapvrplerirqhvdaadddggtt
sitatvkingveteisgsgngplaafvhaladvgfdvavldyyehamsagddaqaaayve
asvtiastsktvwgvgiapsittaslravvsavnraa