PDB entry 1sr4

View 1sr4 on RCSB PDB site
Description: Crystal Structure of the Haemophilus ducreyi cytolethal distending toxin
Class: toxin
Keywords: toxin, bacterial, Haemophilus ducreyi, virulence, DNA Damage, genotoxin, cytotoxins, Cell Cycle, Apoptosis, lectin, Deoxyribonuclease I
Deposited on 2004-03-22, released 2004-06-15
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.182
AEROSPACI score: 0.46 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Cytolethal distending toxin subunit A
    Species: Haemophilus ducreyi [TaxId:730]
    Gene: CDTA, HD0902
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1sr4a_
  • Chain 'B':
    Compound: cytolethal distending toxin protein B
    Species: Haemophilus ducreyi [TaxId:730]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1sr4b_
  • Chain 'C':
    Compound: cytolethal distending toxin protein C
    Species: Haemophilus ducreyi [TaxId:730]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1sr4c_
  • Heterogens: BR, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1sr4A (A:)
snqrmndysqpesqsdlapksstiqpqpqpllsktpsmslnllsssgpnrqvlpsepsnf
mtlmgqngalltvwalakrnwlwaypniysqdfgnirnwkmepgkhreyfrfvnqslgtc
veaygnglihdicsldklaqefellptdsgavviksvsqgrcvtynpvsttfystvtlsv
cdgatepsrdqtwylappvleatavn

    Sequence, based on observed residues (ATOM records): (download) 
    >1sr4A (A:)
lnllsssgpnrqvlpsepsnfmtlmgqngalltvwalakrnwlwaypniysqdfgnirnw
kmepgkhreyfrfvnqslgtcveaygnglihdicsldklaqefellptdsgavviksvsq
grcvtynpvsttfystvtlsvcdgatepsrdqtwylappvleatavn

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1sr4B (B:)
nlsdfkvatwnlqgssavneskwninvrqllsgeqgadilmvqeagslpssavrtsrviq
hggtpieeytwnlgtrsrpnmvyiyysrldvganrvnlaivsrrqadeafivhsdssvlq
srpavgirigtdvfftvhalatggsdavslirnifttfnsssspperrvyswmvvgdfnr
apanlevalrqepavsentiiiaptepthrsgnildyailhdahlprreqarerigaslm
lnqlrsqitsdhfpvsfvrdr

    Sequence, based on observed residues (ATOM records): (download) 
    >1sr4B (B:)
nlsdfkvatwnlqgssavneskwninvrqllsgeqgadilmvqeagslpssavrtsrviq
hggtpieeytwnlgtrsrpnmvyiyysrldvganrvnlaivsrrqadeafivhsdssvlq
srpavgirigtdvfftvhalatggsdavslirnifttfnspperrvyswmvvgdfnrapa
nlevalrqepavsentiiiaptepthrsgnildyailhdahlprreqarerigaslmlnq
lrsqitsdhfpvsfvrdr

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1sr4C (C:)
esnpdpttypdvelsppprislrslltaqpvkndhydshnylsthwelidykgkeyeklr
dggtlvqfkvvgaakcfaflgkgttdckdtdhtvfnliptntgaflikdallgfcitshd
fddlklepcggsvsgrtfslayqwgilppfgpskilippvrrnqgs

    Sequence, based on observed residues (ATOM records): (download) 
    >1sr4C (C:)
dpttypdvelsppprislrslltaqpvkndhydshnylsthwelidykgkeyeklrdggt
lvqfkvvgaakcfaflgkgttdckdtdhtvfnliptntgaflikdallgfcitshdfddl
klepcggsvsgrtfslayqwgilppfgpskilip