PDB entry 1so8

View 1so8 on RCSB PDB site
Description: Abeta-bound human ABAD structure [also known as 3-hydroxyacyl-CoA dehydrogenase type II (Type II HADH), Endoplasmic reticulum-associated amyloid beta-peptide binding protein (ERAB)]
Class: oxidoreductase
Keywords: alcohol dehydrogenase; Rossmann fold; Abeta-induced distorsion
Deposited on 2004-03-13, released 2004-05-11
The last revision prior to the SCOP 1.75 freeze date was dated 2004-05-11, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.231
AEROSPACI score: 0.47 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 3-hydroxyacyl-CoA dehydrogenase type II
    Species: HOMO SAPIENS
    Gene: HADH2, ERAB, XH98G2, SCHAD
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1so8a_
  • Heterogens: NA, CL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1so8A (A:)
maaacrsvkglvavitggasglglataerlvgqgasavlldlpnsggeaqakklgnncvf
apadvtsekdvqtalalakgkfgrvdvavncagiavasktynlkkgqthtledfqrvldv
nlmgtfnvirlvagemgqnepdqggqrgviintasvaafegqvgqaaysaskggivgmtl
piardlapigirvmtiapglfgtplltslpekvcnflasqvpfpsrlgdpaeyahlvqai
ienpflngevirldgairmqp

    Sequence, based on observed residues (ATOM records): (download) 
    >1so8A (A:)
rsvkglvavitggasglglataerlvgqgasavlldlpnsggeaqakklgnncvfapadv
tsekdvqtalalakgkfgrvdvavncagifqrvldvnlmgtfnvirlvagemgqnepdqg
gqrgviintasvaafegqvgqaaysaskggivgmtlpiardlapigirvmtiapglfgtp
lltdpaeyahlvqaiienpflngevirl