PDB entry 1sl0

View 1sl0 on RCSB PDB site
Description: Ternary 3' complex of T7 DNA polymerase with a DNA primer/template containing a disordered cis-syn thymine dimer on the template and an incoming nucleotide
Class: transferase/electron transport/DNA
Keywords: DNA polymerase, fidelity, lesion bypass, thymine dimer, open, close, TRANSFERASE/ELECTRON TRANSPORT/DNA COMPLEX
Deposited on 2004-03-05, released 2004-07-06
The last revision prior to the SCOPe 2.07 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 3.2 Å
R-factor: 0.282
AEROSPACI score: 0.11 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: DNA polymerase
    Species: Enterobacteria phage T7 [TaxId:10760]
    Gene: 5
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1sl0a1, d1sl0a2
  • Chain 'B':
    Compound: Thioredoxin 1
    Species: Escherichia coli [TaxId:562]
    Gene: TRXA, TSNC, FIPA, B3781, C4701, Z5291, ECS4714, STM3915, STMD1.75, STY3639, T3381, SF3854, S3905
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1sl0b_
  • Chain 'C':
    Compound: DNA polymerase
    Species: Enterobacteria phage T7 [TaxId:10760]
    Gene: 5
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1sl0c1, d1sl0c2
  • Chain 'D':
    Compound: Thioredoxin 1
    Species: Escherichia coli [TaxId:562]
    Gene: TRXA, TSNC, FIPA, B3781, C4701, Z5291, ECS4714, STM3915, STMD1.75, STY3639, T3381, SF3854, S3905
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1sl0d_
  • Chain 'P':
    Compound: 5'-d(*cp*gp*ap*ap*ap*ap*cp*gp*ap*cp*gp*gp*cp*cp*ap*gp*tp*gp*cp*cp*(2dt))-3'
  • Chain 'Q':
    Compound: 5'-d(*cp*gp*ap*ap*ap*ap*cp*gp*ap*cp*gp*gp*cp*cp*ap*gp*tp*gp*cp*cp*(2dt))-3'
  • Chain 'T':
    Compound: 5'-d(*cp*cp*cp*(ttd)p*ap*gp*gp*cp*ap*cp*tp*gp*gp*cp*cp*gp*tp*cp*gp*tp*tp*tp*tp*cp*g)-3'
  • Chain 'U':
    Compound: 5'-d(*cp*cp*cp*(ttd)p*ap*gp*gp*cp*ap*cp*tp*gp*gp*cp*cp*gp*tp*cp*gp*tp*tp*tp*tp*cp*g)-3'
  • Heterogens: MG, DAD

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1sl0A (A:)
mivsdieanallesvtkfhcgviydystaeyvsyrpsdfgayldaleaevargglivfhn
ghkydvpaltklaklqlnrefhlprencidtlvlsrlihsnlkdtdmgllrsgklpgale
awgyrlgemkgeykddfkrmleeqgeeyvdgmewwnfneemmdynvqdvvvtkallekll
sdkhyfppeidftdvgyttfwsesleavdiehraawllakqerngfpfdtkaieelyvel
aarrsellrkltetfgswyqpkggtemfchprtgkplpkypriktpkvggifkkpknkaq
regrepceldtreyvagapytpvehvvfnpssrdhiqkklqeagwvptkytdkgapvvdd
evlegvrvddpekqaaidlikeylmiqkrigqsaegdkawlryvaedgkihgsvnpngav
tgrathafpnlaqipgvrspygeqcraafgaehhldgitgkpwvqagidasglelrclah
fmarfdngeyaheilngdihtknqiaaelptrdnaktfiygflygagdekigqivgagke
rgkelkkkflentpaiaalresiqqtlvessqwvageqqvkwkrrwikgldgrkvhvrsp
haalntllqsagalicklwiikteemlvekglkhgwdgdfaymawvhdeiqvgcrteeia
qvvietaqeamrwvgdhwnfrclldtegkmgpnwaich

    Sequence, based on observed residues (ATOM records): (download) 
    >1sl0A (A:)
mivsdieanallesvtkfhcgviydystaeyvsyrpsdfgayldaleaevargglivfhn
ghkydvpaltklaklqlnrefhlprencidtlvlsrlihsnlkdtdmgllrsgklpgale
awgyrlgemkgeykddfkrmleeqgeeyvdgmewwnfneemmdynvqdvvvtkallekll
sdkhyfppeidftdvgyttfwsesleavdiehraawllakqerngfpfdtkaieelyvel
aarrsellrkltetfgswyqpkggtemfchprtgkplpkypriktpvgdtreyvaapytp
vehvvfnpssrdhiqkklqeagwvptkytdkgapvvddevlegvrvddpekqaaidlike
ylmiqkrigqsaegdkawlryvaedgkihgsvnpngavtgrathafpnlaqipgvrspyg
eqcraafgaehhldgitgkpwvqagidasglelrclahfmarfdngeyaheilngdihtk
nqiaaelptrdnaktfiygfkigqivgagkergkelkkkflentpaiaalresiqqtlve
kwkrrwikgldgrkvhvrsphaalntllqsagalicklwiikteemlvekglkhgwdgdf
aymawvhdeiqvgcrteeiaqvvietaqeamrwvgdhwnfrclldtegkmgpnwaich

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1sl0B (B:)
sdkiihltddsfdtdvlkadgailvdfwaewcgpckmiapildeiadeyqgkltvaklni
dqnpgtapkygirgiptlllfkngevaatkvgalskgqlkefldanla

    Sequence, based on observed residues (ATOM records): (download) 
    >1sl0B (B:)
kiihltddsfdtdvlkadgailvdfwaewcgpckmiapildeiadeyqgkltvaklnidq
npgtapkygirgiptlllfkngevaatkvgalskgqlkefldanl

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1sl0C (C:)
mivsdieanallesvtkfhcgviydystaeyvsyrpsdfgayldaleaevargglivfhn
ghkydvpaltklaklqlnrefhlprencidtlvlsrlihsnlkdtdmgllrsgklpgale
awgyrlgemkgeykddfkrmleeqgeeyvdgmewwnfneemmdynvqdvvvtkallekll
sdkhyfppeidftdvgyttfwsesleavdiehraawllakqerngfpfdtkaieelyvel
aarrsellrkltetfgswyqpkggtemfchprtgkplpkypriktpkvggifkkpknkaq
regrepceldtreyvagapytpvehvvfnpssrdhiqkklqeagwvptkytdkgapvvdd
evlegvrvddpekqaaidlikeylmiqkrigqsaegdkawlryvaedgkihgsvnpngav
tgrathafpnlaqipgvrspygeqcraafgaehhldgitgkpwvqagidasglelrclah
fmarfdngeyaheilngdihtknqiaaelptrdnaktfiygflygagdekigqivgagke
rgkelkkkflentpaiaalresiqqtlvessqwvageqqvkwkrrwikgldgrkvhvrsp
haalntllqsagalicklwiikteemlvekglkhgwdgdfaymawvhdeiqvgcrteeia
qvvietaqeamrwvgdhwnfrclldtegkmgpnwaich

    Sequence, based on observed residues (ATOM records): (download) 
    >1sl0C (C:)
mivsdieanallesvtkfhcgviydystaeyvsyrpsdfgayldaleaevargglivfhn
ghkydvpaltklaklqlnrefhlprencidtlvlsrlihsnlkdtdmgllrsgklpgale
awgyrlgemkgeykddfkrmleeqgeeyvdgmewwnfneemmdynvqdvvvtkallekll
sdkhyfppeidftdvgyttfwsesleavdiehraawllakqerngfpfdtkaieelyvel
aarrsellrkltetfgswyqpkggtemfchprtgkplpkypriktpvgdtreyvaapytp
vehvvfnpssrdhiqkklqeagwvptkytdkgapvvddevlegvrvddpekqaaidlike
ylmiqkrigqsaegdkawlryvaedgkihgsvnpngavtgrathafpnlaqipgvrspyg
eqcraafgaehhldgitgkpwvqagidasglelrclahfmarfdngeyaheilngdihtk
nqiaaelptrdnaktfiygfkigqivgagkergkelkkkflentpaiaalresiqqtlve
kwkrrwikgldgrkvhvrsphaalntllqsagalicklwiikteemlvekglkhgwdgdf
aymawvhdeiqvgcrteeiaqvvietaqeamrwvgdhwnfrclldtegkmgpnwaich

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1sl0D (D:)
sdkiihltddsfdtdvlkadgailvdfwaewcgpckmiapildeiadeyqgkltvaklni
dqnpgtapkygirgiptlllfkngevaatkvgalskgqlkefldanla

    Sequence, based on observed residues (ATOM records): (download) 
    >1sl0D (D:)
kiihltddsfdtdvlkadgailvdfwaewcgpckmiapildeiadeyqgkltvaklnidq
npgtapkygirgiptlllfkngevaatkvgalskgqlkefldanl

  • Chain 'P':
    No sequence available.

  • Chain 'Q':
    No sequence available.

  • Chain 'T':
    No sequence available.

  • Chain 'U':
    No sequence available.