PDB entry 1sio

View 1sio on RCSB PDB site
Description: Structure of Kumamolisin-As complexed with a covalently-bound inhibitor, AcIPF
Class: hydrolase/hydrolase inhibitor
Keywords: kumamolisin-as, hydrolase-hydrolase inhibitor complex
Deposited on 2004-03-01, released 2004-03-30
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: 0.173
AEROSPACI score: 0.5 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: kumamolisin-As
    Species: Alicyclobacillus sendaiensis [TaxId:192387]
    Database cross-references and differences (RAF-indexed):
    • GB BAC41257 (0-End)
    Domains in SCOPe 2.08: d1sioa_
  • Chain 'B':
    Compound: kumamolisin-As
    Species: Alicyclobacillus sendaiensis [TaxId:192387]
    Database cross-references and differences (RAF-indexed):
    • GB BAC41257
    Domains in SCOPe 2.08: d1siob_
  • Chain 'C':
    Compound: kumamolisin-As
    Species: Alicyclobacillus sendaiensis [TaxId:192387]
    Database cross-references and differences (RAF-indexed):
    • GB BAC41257
    Domains in SCOPe 2.08: d1sioc_
  • Chain 'D':
    Compound: Ace-ILE-PRO-PHL peptide inhibitor
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
    • PDB 1SIO (Start-2)
  • Chain 'E':
    Compound: Ace-ILE-PRO-PHL peptide inhibitor
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
    • PDB 1SIO (Start-2)
  • Chain 'F':
    Compound: Ace-ILE-PRO-PHL peptide inhibitor
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
    • PDB 1SIO (Start-2)
  • Heterogens: SO4, CA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1sioA (A:)
aaptaytpldvaqayqfpegldgqgqciaiielgggydeaslaqyfaslgvpapqvvsvs
vdgasnqptgdpsgpdgeveldievagalapgakfavyfapntdagfldaittaihdptl
kpsvvsiswggpedswtsaaiaamnrafldaaalgvtvlaaagdsgstdgeqdglyhvdf
paaspyvlacggtrlvasggriaqetvwndgpdggatgggvsrifplpawqehanvppsa
npgassgrgvpdlagnadpatgyevvidgeatviggtsavaplfaalvarinqklgkavg
ylnptlyqlpadvfhditegnndianraqiyqagpgwdpctglgspigvrllqallpsas
qpqp

    Sequence, based on observed residues (ATOM records): (download) 
    >1sioA (A:)
aaptaytpldvaqayqfpegldgqgqciaiielgggydeaslaqyfaslgvpapqvvsvs
vdgasnqptgdpsgpdgeveldievagalapgakfavyfapntdagfldaittaihdptl
kpsvvsiswggpedswtsaaiaamnrafldaaalgvtvlaaagdsgstdgeqdglyhvdf
paaspyvlacggtrlvasggriaqetvwndgpdggatgggvsrifplpawqehanvppsa
npgassgrgvpdlagnadpatgyevvidgeatviggtsavaplfaalvarinqklgkavg
ylnptlyqlpadvfhditegnndianraqiyqagpgwdpctglgspigvrllqallp

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1sioB (B:)
aaptaytpldvaqayqfpegldgqgqciaiielgggydeaslaqyfaslgvpapqvvsvs
vdgasnqptgdpsgpdgeveldievagalapgakfavyfapntdagfldaittaihdptl
kpsvvsiswggpedswtsaaiaamnrafldaaalgvtvlaaagdsgstdgeqdglyhvdf
paaspyvlacggtrlvasggriaqetvwndgpdggatgggvsrifplpawqehanvppsa
npgassgrgvpdlagnadpatgyevvidgeatviggtsavaplfaalvarinqklgkavg
ylnptlyqlpadvfhditegnndianraqiyqagpgwdpctglgspigvrllqallpsas
qpqp

    Sequence, based on observed residues (ATOM records): (download) 
    >1sioB (B:)
aptaytpldvaqayqfpegldgqgqciaiielgggydeaslaqyfaslgvpapqvvsvsv
dgasnqptgdpsgpdgeveldievagalapgakfavyfapntdagfldaittaihdptlk
psvvsiswggpedswtsaaiaamnrafldaaalgvtvlaaagdsgstdgeqdglyhvdfp
aaspyvlacggtrlvasggriaqetvwndgpdggatgggvsrifplpawqehanvppsan
pgassgrgvpdlagnadpatgyevvidgeatviggtsavaplfaalvarinqklgkavgy
lnptlyqlpadvfhditegnndianraqiyqagpgwdpctglgspigvrllqallp

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1sioC (C:)
aaptaytpldvaqayqfpegldgqgqciaiielgggydeaslaqyfaslgvpapqvvsvs
vdgasnqptgdpsgpdgeveldievagalapgakfavyfapntdagfldaittaihdptl
kpsvvsiswggpedswtsaaiaamnrafldaaalgvtvlaaagdsgstdgeqdglyhvdf
paaspyvlacggtrlvasggriaqetvwndgpdggatgggvsrifplpawqehanvppsa
npgassgrgvpdlagnadpatgyevvidgeatviggtsavaplfaalvarinqklgkavg
ylnptlyqlpadvfhditegnndianraqiyqagpgwdpctglgspigvrllqallpsas
qpqp

    Sequence, based on observed residues (ATOM records): (download) 
    >1sioC (C:)
taytpldvaqayqfpegldgqgqciaiielgggydeaslaqyfaslgvpapqvvsvsvdg
asnqptgdpsgpdgeveldievagalapgakfavyfapntdagfldaittaihdptlkps
vvsiswggpedswtsaaiaamnrafldaaalgvtvlaaagdsgstdgeqdglyhvdfpaa
spyvlacggtrlvasggriaqetvwndgpdggatgggvsrifplpawqehanvppsanpg
assgrgvpdlagnadpatgyevvidgeatviggtsavaplfaalvarinqklgkavgyln
ptlyqlpadvfhditegnndianraqiyqagpgwdpctglgspigvrllqall

  • Chain 'D':
    No sequence available.

  • Chain 'E':
    No sequence available.

  • Chain 'F':
    No sequence available.