PDB entry 1sg6

View 1sg6 on RCSB PDB site
Description: Crystal structure of Aspergillus nidulans 3-dehydroquinate synthase (AnDHQS) in complex with Zn2+ and NAD+, at 1.7D
Class: lyase
Keywords: shikimate pathway, aromatic amino acid biosynthesis, dhqs, open form, form j, domain movement, cyclase, lyase
Deposited on 2004-02-23, released 2004-08-31
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-11-16, with a file datestamp of 2011-11-11.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: 0.195
AEROSPACI score: 0.54 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Pentafunctional AROM polypeptide
    Species: Emericella nidulans [TaxId:162425]
    Gene: AROMA, AROM
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1sg6a_
  • Chain 'B':
    Compound: Pentafunctional AROM polypeptide
    Species: Emericella nidulans [TaxId:162425]
    Gene: AROMA, AROM
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1sg6b_
  • Heterogens: ZN, NAD, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1sg6A (A:)
msnptkisilgresiiadfglwrnyvakdlisdcssttyvlvtdtnigsiytpsfeeafr
kraaeitpsprlliynrppgevsksrqtkadiedwmlsqnppcgrdtvvialgggvigdl
tgfvastymrgvryvqvpttllamvdssiggktaidtplgknligaiwqptkiyidlefl
etlpvrefingmaeviktaaisseeeftaleenaetilkavrrevtpgehrfegteeilk
arilasarhkayvvsaderegglrnllnwghsighaieailtpqilhgecvaigmvkeae
larhlgilkgvavsrivkclaayglptslkdarirkltagkhcsvdqlmfnmaldkkndg
pkkkivllsaigtpyetrasvvanedirvvlap

    Sequence, based on observed residues (ATOM records): (download) 
    >1sg6A (A:)
ptkisilgresiiadfglwrnyvakdlisdcssttyvlvtdtnigsiytpsfeeafrkra
aeitpsprlliynrppgevsksrqtkadiedwmlsqnppcgrdtvvialgggvigdltgf
vastymrgvryvqvpttllamvdssiggktaidtplgknligaiwqptkiyidlefletl
pvrefingmaeviktaaisseeeftaleenaetilkavrrevtpgehrfegteeilkari
lasarhkayvvsaglrnllnwghsighaieailtpqilhgecvaigmvkeaelarhlgil
kgvavsrivkclaayglptslkdarirkltagkhcsvdqlmfnmaldkkivllsaigtpy
etrasvvanedirvvla

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1sg6B (B:)
msnptkisilgresiiadfglwrnyvakdlisdcssttyvlvtdtnigsiytpsfeeafr
kraaeitpsprlliynrppgevsksrqtkadiedwmlsqnppcgrdtvvialgggvigdl
tgfvastymrgvryvqvpttllamvdssiggktaidtplgknligaiwqptkiyidlefl
etlpvrefingmaeviktaaisseeeftaleenaetilkavrrevtpgehrfegteeilk
arilasarhkayvvsaderegglrnllnwghsighaieailtpqilhgecvaigmvkeae
larhlgilkgvavsrivkclaayglptslkdarirkltagkhcsvdqlmfnmaldkkndg
pkkkivllsaigtpyetrasvvanedirvvlap

    Sequence, based on observed residues (ATOM records): (download) 
    >1sg6B (B:)
nptkisilgresiiadfglwrnyvakdlisdcssttyvlvtdtnigsiytpsfeeafrkr
aaeitpsprlliynrppgevsksrqtkadiedwmlsqnppcgrdtvvialgggvigdltg
fvastymrgvryvqvpttllamvdssiggktaidtplgknligaiwqptkiyidleflet
lpvrefingmaeviktaaisseeeftaleenaetilkavrrevtpgehrfegteeilkar
ilasarhkayvvsagglrnllnwghsighaieailtpqilhgecvaigmvkeaelarhlg
ilkgvavsrivkclaayglptslkdarirkltagkhcsvdqlmfnmalkkivllsaigtp
yetrasvvanedirvvla