PDB entry 1sck

View 1sck on RCSB PDB site
Description: K236L mutant of hydroxynitrile lyase from Hevea brasiliensis in complex with acetone
Class: lyase
Keywords: alpha-beta hydrolase fold, substrate complex, catalytic triad, lyase
Deposited on 2004-02-12, released 2004-06-29
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-10-11, with a file datestamp of 2017-10-06.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: N/A
AEROSPACI score: 0.4 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: (s)-acetone-cyanohydrin lyase
    Species: Hevea brasiliensis [TaxId:3981]
    Gene: HNL
    Database cross-references and differences (RAF-indexed):
    • Uniprot P52704 (Start-256)
      • engineered (235)
    Domains in SCOPe 2.08: d1scka_
  • Heterogens: SO4, ACN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1sckA (A:)
mafahfvlihtichgawiwhklkpllealghkvtaldlaasgvdprqieeigsfdeysep
lltflealppgekvilvgescgglniaiaadkycekiaaavfhnsvlpdtehcpsyvvdk
lmevfpdwkdttyftytkdgkeitglklgftllrenlytlcgpeeyelakmltrkgslfq
nilakrpfftkegygsikkiyvwtdqdeiflpefqlwqienykpdkvykveggdhllqlt
ktkeiaeilqevadtyn

    Sequence, based on observed residues (ATOM records): (download) 
    >1sckA (A:)
afahfvlihtichgawiwhklkpllealghkvtaldlaasgvdprqieeigsfdeysepl
ltflealppgekvilvgescgglniaiaadkycekiaaavfhnsvlpdtehcpsyvvdkl
mevfpdwkdttyftytkdgkeitglklgftllrenlytlcgpeeyelakmltrkgslfqn
ilakrpfftkegygsikkiyvwtdqdeiflpefqlwqienykpdkvykveggdhllqltk
tkeiaeilqevadtyn