PDB entry 1sc8

View 1sc8 on RCSB PDB site
Description: Urokinase Plasminogen Activator B-Chain-J435 Complex
Class: hydrolase
Keywords: urokinase, inhibitor, serine protease, human
Deposited on 2004-02-12, released 2004-06-22
The last revision prior to the SCOP 1.75 freeze date was dated 2004-12-14, with a file datestamp of 2007-06-28.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: 0.24
AEROSPACI score: 0.41 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'U':
    Compound: Plasminogen activator, urokinase
    Species: HOMO SAPIENS
    Gene: homo
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00749 (Start-261)
      • engineered (135)
    Domains in SCOP 1.75: d1sc8u_
  • Heterogens: SO4, 2IN, HOH

PDB Chain Sequences:

  • Chain 'U':
    Sequence, based on SEQRES records: (download) 
    >1sc8U (U:)
lkfqcgqktlrprfkiiggefttienqpwfaaiyrrhrggsvtyvcggslispcwvisat
hcfidypkkedyivylgrsrlnsntqgemkfevenlilhkdysadtlahhndiallkirs
kegrcaqpsrtiqtislpsmyndpqfgtsceitgfgkenstdylypeqlkmtvvklishr
ecqqphyygsevttkmlcaadpqwktdscqgdsggplvcslqgrmtltgivswgrgcalk
dkpgvytrvshflpwirshtke

    Sequence, based on observed residues (ATOM records): (download) 
    >1sc8U (U:)
iiggefttienqpwfaaiyrrhrggsvtyvcggslispcwvisathcfidypkkedyivy
lgrsrlnsntqgemkfevenlilhkdysadtlahhndiallkirskegrcaqpsrtiqti
slpsmyndpqfgtsceitgfgkenstdylypeqlkmtvvklishrecqqphyygsevttk
mlcaadpqwktdscqgdsggplvcslqgrmtltgivswgrgcalkdkpgvytrvshflpw
irshtke