PDB entry 1sa1

View 1sa1 on RCSB PDB site
Description: Tubulin-podophyllotoxin: stathmin-like domain complex
Class: cell cycle
Keywords: alpha-tubulin, beta-tubulin, colchicine, gtpase, microtubule podophyllotoxin, stathmin, tubulin, cell cycle
Deposited on 2004-02-06, released 2004-03-23
The last revision prior to the SCOPe 2.07 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 4.2 Å
R-factor: 0.206
AEROSPACI score: 0.04 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Tubulin alpha chain
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P02550
      • see remark 999 (264)
    Domains in SCOPe 2.07: d1sa1a1, d1sa1a2
  • Chain 'B':
    Compound: Tubulin beta chain
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1sa1b1, d1sa1b2
  • Chain 'C':
    Compound: Tubulin alpha chain
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P02550
      • see remark 999 (264)
    Domains in SCOPe 2.07: d1sa1c1, d1sa1c2
  • Chain 'D':
    Compound: Tubulin beta chain
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1sa1d1, d1sa1d2
  • Chain 'E':
    Compound: Stathmin 4
    Species: Rattus norvegicus [TaxId:10116]
    Gene: STMN4
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1sa1e_
  • Heterogens: MG, GTP, GDP, POD

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1sa1A (A:)
mrecisihvgqagvqignacwelyclehgiqpdgqmpsdktigggddsfntffsetgagk
hvpravfvdleptvidevrtgtyrqlfhpeqlitgkedaannyarghytigkeiidlvld
rirkladqctglqgfsvfhsfgggtgsgftsllmerlsvdygkksklefsiypapqvsta
vvepynsiltthttlehsdcafmvdneaiydicrrnldierptytnlnrligqivssita
slrfdgalnvdltefqtnlvpyprihfplatyapvisaekayheqlsvaeitnacfepan
qmvkcdprhgkymaccllyrgdvvpkdvnaaiatiktkrtiqfvdwcptgfkvginyepp
tvvpggdlakvqravcmlsnttaiaeawarldhkfdlmyakrafvhwyvgegmeegefse
aredmaalekdyeevgvdsvegegeeegeey

    Sequence, based on observed residues (ATOM records): (download) 
    >1sa1A (A:)
recisihvgqagvqignacwelyclehgiqpdgqmpsdgddsfntffsetgagkhvprav
fvdleptvidevrtgtyrqlfhpeqlitgkedaannyarghytigkeiidlvldrirkla
dqctglqgfsvfhsfgggtgsgftsllmerlsvdygkksklefsiypapqvstavvepyn
siltthttlehsdcafmvdneaiydicrrnldierptytnlnrligqivssitaslrfdg
alnvdltefqtnlvpyprihfplatyapvisaekayheqlsvaeitnacfepanqmvkcd
prhgkymaccllyrgdvvpkdvnaaiatiktkrtiqfvdwcptgfkvginyepptvvpgg
dlakvqravcmlsnttaiaeawarldhkfdlmyakrafvhwyvgegmeegefsearedma
alekdyeevgvds

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1sa1B (B:)
mreivhiqagqcgnqigakfwevisdehgidptgsyhgdsdlqlerinvyyneaagnkyv
prailvdlepgtmdsvrsgpfgqifrpdnfvfgqsgagnnwakghytegaelvdsvldvv
rkesescdclqgfqlthslgggtgsgmgtlliskireeypdrimntfsvvpspkvsdtvv
epynatlsvhqlventdetycidnealydicfrtlklttptygdlnhlvsatmsgvttcl
rfpgqlnadlrklavnmvpfprlhffmpgfapltsrgsqqyraltvpeltqqmfdaknmm
aacdprhgryltvaavfrgrmsmkevdeqmlnvqnknssyfvewipnnvktavcdipprg
lkmsatfignstaiqelfkriseqftamfrrkaflhwytgegmdemefteaesnmndlvs
eyqqyqdatadeqgefeeegeedea

    Sequence, based on observed residues (ATOM records): (download) 
    >1sa1B (B:)
reivhiqagqcgnqigakfwevisdehgidptgsyhgdsdlqlerinvyyneaagnkyvp
railvdlepgtmdsvrsgpfgqifrpdnfvfgqsgagnnwakghytegaelvdsvldvvr
kesescdclqgfqlthslgggtgsgmgtlliskireeypdrimntfsvvpspkvsdtvve
pynatlsvhqlventdetycidnealydicfrtlklttptygdlnhlvsatmsgvttclr
fpgqlnadlrklavnmvpfprlhffmpgfapltqyraltvpeltqqmfdaknmmaacdpr
hgryltvaavfrgrmsmkevdeqmlnvqnknssyfvewipnnvktavcdipprglkmsat
fignstaiqelfkriseqftamfrrkaflhwytgegmdemefteaesnmndlvseyqqyq
da

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1sa1C (C:)
mrecisihvgqagvqignacwelyclehgiqpdgqmpsdktigggddsfntffsetgagk
hvpravfvdleptvidevrtgtyrqlfhpeqlitgkedaannyarghytigkeiidlvld
rirkladqctglqgfsvfhsfgggtgsgftsllmerlsvdygkksklefsiypapqvsta
vvepynsiltthttlehsdcafmvdneaiydicrrnldierptytnlnrligqivssita
slrfdgalnvdltefqtnlvpyprihfplatyapvisaekayheqlsvaeitnacfepan
qmvkcdprhgkymaccllyrgdvvpkdvnaaiatiktkrtiqfvdwcptgfkvginyepp
tvvpggdlakvqravcmlsnttaiaeawarldhkfdlmyakrafvhwyvgegmeegefse
aredmaalekdyeevgvdsvegegeeegeey

    Sequence, based on observed residues (ATOM records): (download) 
    >1sa1C (C:)
recisihvgqagvqignacwelyclehgiqpdgqmpsdsfntffsetgagkhvpravfvd
leptvidevrtgtyrqlfhpeqlitgkedaannyarghytigkeiidlvldrirkladqc
tglqgfsvfhsfgggtgsgftsllmerlsvdygkksklefsiypapqvstavvepynsil
tthttlehsdcafmvdneaiydicrrnldierptytnlnrligqivssitaslrfdgaln
vdltefqtnlvpyprihfplatyapvisaekayheqlsvaeitnacfepanqmvkcdprh
gkymaccllyrgdvvpkdvnaaiatiktkrtiqfvdwcptgfkvginyepptvvpggdla
kvqravcmlsnttaiaeawarldhkfdlmyakrafvhwyvgegmeegefsearedmaale
kdyeevgvds

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1sa1D (D:)
mreivhiqagqcgnqigakfwevisdehgidptgsyhgdsdlqlerinvyyneaagnkyv
prailvdlepgtmdsvrsgpfgqifrpdnfvfgqsgagnnwakghytegaelvdsvldvv
rkesescdclqgfqlthslgggtgsgmgtlliskireeypdrimntfsvvpspkvsdtvv
epynatlsvhqlventdetycidnealydicfrtlklttptygdlnhlvsatmsgvttcl
rfpgqlnadlrklavnmvpfprlhffmpgfapltsrgsqqyraltvpeltqqmfdaknmm
aacdprhgryltvaavfrgrmsmkevdeqmlnvqnknssyfvewipnnvktavcdipprg
lkmsatfignstaiqelfkriseqftamfrrkaflhwytgegmdemefteaesnmndlvs
eyqqyqdatadeqgefeeegeedea

    Sequence, based on observed residues (ATOM records): (download) 
    >1sa1D (D:)
reivhiqagqcgnqigakfwevisdehgidptgsyhgdsdlqlerinvyyneaagnkyvp
railvdlepgtmdsvrsgpfgqifrpdnfvfgqsgagnnwakghytegaelvdsvldvvr
kesescdclqgfqlthslgggtgsgmgtlliskireeypdrimntfsvvpspkvsdtvve
pynatlsvhqlventdetycidnealydicfrtlklttptygdlnhlvsatmsgvttclr
fpgqlnadlrklavnmvpfprlhffmpgfapltsrgsqqyraltvpeltqqmfdaknmma
acdprhgryltvaavfrgrmsmkevdeqmlnvqnknssyfvewipnnvktavcdipprgl
kmsatfignstaiqelfkriseqftamfrrkaflhwytgegmdemefteaesnmndlvse
yqqyqd

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >1sa1E (E:)
admevielnkctsgqsfevilkppsfdgvpefnaslprrrdpsleeiqkkleaaeerrky
qeaellkhlaekrehereviqkaieennnfikmakeklaqkmesnkenreahlaamlerl
qekdkhaeevrknkelkeeasr

    Sequence, based on observed residues (ATOM records): (download) 
    >1sa1E (E:)
mevielnkctsgqsfevilkppsfdgvpefnaslprrpsleeiqkkleaaeerrkyqeae
llkhlaekrehereviqkaieennnfikmakeklaqkmesnkenreahlaamlerlqekd
khaeevrknkelke