PDB entry 1sa0

View 1sa0 on RCSB PDB site
Description: tubulin-colchicine: stathmin-like domain complex
Class: cell cycle
Keywords: alpha-tubulin, beta-tubulin, colchicine, gtpase, microtubule podophyllotoxin, stathmin, tubulin
Deposited on 2004-02-06, released 2004-03-23
The last revision prior to the SCOP 1.73 freeze date was dated 2004-03-23, with a file datestamp of 2007-06-28.
Experiment type: XRAY
Resolution: 3.58 Å
R-factor: 0.233
AEROSPACI score: 0.06 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Tubulin alpha chain
    Species: BOS TAURUS
    Database cross-references and differences (RAF-indexed):
    • Uniprot P02550
      • see remark 999 (264)
    Domains in SCOP 1.73: d1sa0a1, d1sa0a2
  • Chain 'B':
    Compound: Tubulin beta chain
    Species: BOS TAURUS
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1sa0b1, d1sa0b2
  • Chain 'C':
    Compound: Tubulin alpha chain
    Species: BOS TAURUS
    Database cross-references and differences (RAF-indexed):
    • Uniprot P02550
      • see remark 999 (264)
    Domains in SCOP 1.73: d1sa0c1, d1sa0c2
  • Chain 'D':
    Compound: Tubulin beta chain
    Species: BOS TAURUS
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1sa0d1, d1sa0d2
  • Chain 'E':
    Compound: Stathmin 4
    Species: Rattus norvegicus
    Gene: STMN4
    Database cross-references and differences (RAF-indexed):
    • Uniprot P63043 (1-End)
      • see remark 999 (0)
    Domains in SCOP 1.73: d1sa0e_
  • Heterogens: MG, GTP, GDP, CN2

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1sa0A (A:)
mrecisihvgqagvqignacwelyclehgiqpdgqmpsdktigggddsfntffsetgagk
hvpravfvdleptvidevrtgtyrqlfhpeqlitgkedaannyarghytigkeiidlvld
rirkladqctglqgfsvfhsfgggtgsgftsllmerlsvdygkksklefsiypapqvsta
vvepynsiltthttlehsdcafmvdneaiydicrrnldierptytnlnrligqivssita
slrfdgalnvdltefqtnlvpyprihfplatyapvisaekayheqlsvaeitnacfepan
qmvkcdprhgkymaccllyrgdvvpkdvnaaiatiktkrtiqfvdwcptgfkvginyepp
tvvpggdlakvqravcmlsnttaiaeawarldhkfdlmyakrafvhwyvgegmeegefse
aredmaalekdyeevgvdsvegegeeegeey

    Sequence, based on observed residues (ATOM records): (download) 
    >1sa0A (A:)
recisihvgqagvqignacwelyclehgiqpdgqmpdsfntffsetgagkhvpravfvdl
eptvidevrtgtyrqlfhpeqlitgkedaannyarghytigkeiidlvldrirkladqct
glqgfsvfhsfgggtgsgftsllmerlsvdygkksklefsiypapqvstavvepynsilt
thttlehsdcafmvdneaiydicrrnldierptytnlnrligqivssitaslrfdgalnv
dltefqtnlvpyprihfplatyapvisaekayheqlsvaeitnacfepanqmvkcdprhg
kymaccllyrgdvvpkdvnaaiatiktkrtiqfvdwcptgfkvginyepptvvpggdlak
vqravcmlsnttaiaeawarldhkfdlmyakrafvhwyvgegmeegefsearedmaalek
dyeevgv

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1sa0B (B:)
mreivhiqagqcgnqigakfwevisdehgidptgsyhgdsdlqlerinvyyneaagnkyv
prailvdlepgtmdsvrsgpfgqifrpdnfvfgqsgagnnwakghytegaelvdsvldvv
rkesescdclqgfqlthslgggtgsgmgtlliskireeypdrimntfsvvpspkvsdtvv
epynatlsvhqlventdetycidnealydicfrtlklttptygdlnhlvsatmsgvttcl
rfpgqlnadlrklavnmvpfprlhffmpgfapltsrgsqqyraltvpeltqqmfdaknmm
aacdprhgryltvaavfrgrmsmkevdeqmlnvqnknssyfvewipnnvktavcdipprg
lkmsatfignstaiqelfkriseqftamfrrkaflhwytgegmdemefteaesnmndlvs
eyqqyqdatadeqgefeeegeedea

    Sequence, based on observed residues (ATOM records): (download) 
    >1sa0B (B:)
reivhiqagqcgnqigakfwevisdehgidptgsyhgdsdlqlerinvyyneaagnkyvp
railvdlepgtmdsvrsgpfgqifrpdnfvfgqsgagnnwakghytegaelvdsvldvvr
kesescdclqgfqlthslgggtgsgmgtlliskireeypdrimntfsvvpspkvsdtvve
pynatlsvhqlventdetycidnealydicfrtlklttptygdlnhlvsatmsgvttclr
fpgqlnadlrklavnmvpfprlhffmpgfapltsltvpeltqqmfdaknmmaacdprhgr
yltvaavfrgrmsmkevdeqmlnvqnknssyfvewipnnvktavcdipprglkmsatfig
nstaiqelfkriseqftamfrrkaflhwytgegmdemefteaesnmndlvseyqqyqda

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1sa0C (C:)
mrecisihvgqagvqignacwelyclehgiqpdgqmpsdktigggddsfntffsetgagk
hvpravfvdleptvidevrtgtyrqlfhpeqlitgkedaannyarghytigkeiidlvld
rirkladqctglqgfsvfhsfgggtgsgftsllmerlsvdygkksklefsiypapqvsta
vvepynsiltthttlehsdcafmvdneaiydicrrnldierptytnlnrligqivssita
slrfdgalnvdltefqtnlvpyprihfplatyapvisaekayheqlsvaeitnacfepan
qmvkcdprhgkymaccllyrgdvvpkdvnaaiatiktkrtiqfvdwcptgfkvginyepp
tvvpggdlakvqravcmlsnttaiaeawarldhkfdlmyakrafvhwyvgegmeegefse
aredmaalekdyeevgvdsvegegeeegeey

    Sequence, based on observed residues (ATOM records): (download) 
    >1sa0C (C:)
recisihvgqagvqignacwelyclehgiqpdgqmdsfntffsetgagkhvpravfvdle
ptvidevrtgtyrqlfhpeqlitgkedaannyarghytigkeiidlvldrirkladqctg
lqgfsvfhsfgggtgsgftsllmerlsvdygkksklefsiypapqvstavvepynsiltt
httlehsdcafmvdneaiydicrrnldierptytnlnrligqivssitaslrfdgalnvd
ltefqtnlvpyprihfplatyapvisaeqlsvaeitnacfepanqmvkcdprhgkymacc
llyrgdvvpkdvnaaiatiktkrtiqfvdwcptgfkvginyepptvvpggdlakvqravc
mlsnttaiaeawarldhkfdlmyakrafvhwyvgegmeegefsearedmaalekdyeevg
v

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1sa0D (D:)
mreivhiqagqcgnqigakfwevisdehgidptgsyhgdsdlqlerinvyyneaagnkyv
prailvdlepgtmdsvrsgpfgqifrpdnfvfgqsgagnnwakghytegaelvdsvldvv
rkesescdclqgfqlthslgggtgsgmgtlliskireeypdrimntfsvvpspkvsdtvv
epynatlsvhqlventdetycidnealydicfrtlklttptygdlnhlvsatmsgvttcl
rfpgqlnadlrklavnmvpfprlhffmpgfapltsrgsqqyraltvpeltqqmfdaknmm
aacdprhgryltvaavfrgrmsmkevdeqmlnvqnknssyfvewipnnvktavcdipprg
lkmsatfignstaiqelfkriseqftamfrrkaflhwytgegmdemefteaesnmndlvs
eyqqyqdatadeqgefeeegeedea

    Sequence, based on observed residues (ATOM records): (download) 
    >1sa0D (D:)
reivhiqagqcgnqigakfwevisdehgidptgsyhgdsdlqlerinvyyneaagnkyvp
railvdlepgtmdsvrsgpfgqifrpdnfvfgqsgagnnwakghytegaelvdsvldvvr
kesescdclqgfqlthslgggtgsgmgtlliskireeypdrimntfsvvpspkvsdtvve
pynatlsvhqlventdetycidnealydicfrtlklttptygdlnhlvsatmsgvttclr
fpgqlnadlrklavnmvpfprlhffmpgfapltsltvpeltqqmfdaknmmaacdprhgr
yltvaavfrgrmsmkevdeqmlnvqnknssyfvewipnnvktavcdipprglkmsatfig
nstaiqelfkriseqftamfrrkaflhwytgegmdemefteaesnmndlvseyqqyqda

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >1sa0E (E:)
admevielnkctsgqsfevilkppsfdgvpefnaslprrrdpsleeiqkkleaaeerrky
qeaellkhlaekrehereviqkaieennnfikmakeklaqkmesnkenreahlaamlerl
qekdkhaeevrknkelkeeasr

    Sequence, based on observed residues (ATOM records): (download) 
    >1sa0E (E:)
admevielnkctsgqsfevilkppsfdpsleeiqkkleaaeerrkyqeaellkhlaekre
hereviqkaieennnfikmakeklaqkmesnkenreahlaamlerlqekdkhaeevrknk
elke