PDB entry 1s7g

View 1s7g on RCSB PDB site
Description: Structural Basis for the Mechanism and Regulation of Sir2 Enzymes
Class: transcription
Keywords: enzyme, sirtuin, sir2, NAD+, ADP-ribose, TRANSCRIPTION
Deposited on 2004-01-29, released 2004-03-23
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.207
AEROSPACI score: 0.37 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: NAD-dependent deacetylase 2
    Species: Archaeoglobus fulgidus [TaxId:2234]
    Gene: NPDA2, AF0112
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1s7ga_
  • Chain 'B':
    Compound: NAD-dependent deacetylase 2
    Species: Archaeoglobus fulgidus [TaxId:2234]
    Gene: NPDA2, AF0112
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1s7gb_
  • Chain 'C':
    Compound: NAD-dependent deacetylase 2
    Species: Archaeoglobus fulgidus [TaxId:2234]
    Gene: NPDA2, AF0112
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1s7gc_
  • Chain 'D':
    Compound: NAD-dependent deacetylase 2
    Species: Archaeoglobus fulgidus [TaxId:2234]
    Gene: NPDA2, AF0112
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1s7gd_
  • Chain 'E':
    Compound: NAD-dependent deacetylase 2
    Species: Archaeoglobus fulgidus [TaxId:2234]
    Gene: NPDA2, AF0112
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1s7ge_
  • Heterogens: ZN, SO4, NAD, APR, 2PE, P6G, PG4, 1PE, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1s7gA (A:)
medeirkaaeilakskhavvftgagisaesgiptfrgedglwrkydpeevasisgfkrnp
rafwefsmemkdklfaepnpahyaiaelermgivkavitqnidmlhqragsrrvlelhgs
mdkldcldchetydwsefvedfnkgeiprcrkcgsyyvkprvvlfgeplpqrtlfeaiee
akhcdafmvvgsslvvypaaelpyiakkagakmiivnaeptmadpifdvkiigkagevlp
kiveevkrlrsek

    Sequence, based on observed residues (ATOM records): (download) 
    >1s7gA (A:)
medeirkaaeilakskhavvftgagisaesgiptfrgedglwrkydpeevasisgfkrnp
rafwefsmemkdklfaepnpahyaiaelermgivkavitqnidmlhqragsrrvlelhgs
mdkldcldchetydwsefvedfnkgeiprcrkcgsyyvkprvvlfgeplpqrtlfeaiee
akhcdafmvvgsslvvypaaelpyiakkagakmiivnaeptmadpifdvkiigkagevlp
kiveevkrlrse

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1s7gB (B:)
medeirkaaeilakskhavvftgagisaesgiptfrgedglwrkydpeevasisgfkrnp
rafwefsmemkdklfaepnpahyaiaelermgivkavitqnidmlhqragsrrvlelhgs
mdkldcldchetydwsefvedfnkgeiprcrkcgsyyvkprvvlfgeplpqrtlfeaiee
akhcdafmvvgsslvvypaaelpyiakkagakmiivnaeptmadpifdvkiigkagevlp
kiveevkrlrsek

    Sequence, based on observed residues (ATOM records): (download) 
    >1s7gB (B:)
medeirkaaeilakskhavvftgagisaesgiptfrgedglwrkydpeevasisgfkrnp
rafwefsmemkdklfaepnpahyaiaelermgivkavitqnidmlhqragsrrvlelhgs
mdkldcldchetydwsefvedfnkgeiprcrkcgsyyvkprvvlfgeplpqrtlfeaiee
akhcdafmvvgsslvvypaaelpyiakkagakmiivnaeptmadpifdvkiigkagevlp
kiveevkrlrse

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1s7gC (C:)
medeirkaaeilakskhavvftgagisaesgiptfrgedglwrkydpeevasisgfkrnp
rafwefsmemkdklfaepnpahyaiaelermgivkavitqnidmlhqragsrrvlelhgs
mdkldcldchetydwsefvedfnkgeiprcrkcgsyyvkprvvlfgeplpqrtlfeaiee
akhcdafmvvgsslvvypaaelpyiakkagakmiivnaeptmadpifdvkiigkagevlp
kiveevkrlrsek

    Sequence, based on observed residues (ATOM records): (download) 
    >1s7gC (C:)
medeirkaaeilakskhavvftgagisaesgiptfrgedglwrkydpeevasisgfkrnp
rafwefsmemkdklfaepnpahyaiaelermgivkavitqnidmlhqragsrrvlelhgs
mdkldcldchetydwsefvedfnkgeiprcrkcgsyyvkprvvlfgeplpqrtlfeaiee
akhcdafmvvgsslvvypaaelpyiakkagakmiivnaeptmadpifdvkiigkagevlp
kiveevkrlrse

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1s7gD (D:)
medeirkaaeilakskhavvftgagisaesgiptfrgedglwrkydpeevasisgfkrnp
rafwefsmemkdklfaepnpahyaiaelermgivkavitqnidmlhqragsrrvlelhgs
mdkldcldchetydwsefvedfnkgeiprcrkcgsyyvkprvvlfgeplpqrtlfeaiee
akhcdafmvvgsslvvypaaelpyiakkagakmiivnaeptmadpifdvkiigkagevlp
kiveevkrlrsek

    Sequence, based on observed residues (ATOM records): (download) 
    >1s7gD (D:)
edeirkaaeilakskhavvftgagisaglwrkydpeevasisgfkrnprafwefsmemkd
klfaepnpahyaiaelermgivkavitqnidmlhqragsrrvlelhgsmdkldcldchet
ydwsefvedfnkgeiprcrkcgsyyvkprvvlfgeplpqrtlfeaieeakhcdafmvvgs
slvvypaaelpyiakkagakmiivnaeptmadpifdvkiigkagevlpkiveevkrlrse

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >1s7gE (E:)
medeirkaaeilakskhavvftgagisaesgiptfrgedglwrkydpeevasisgfkrnp
rafwefsmemkdklfaepnpahyaiaelermgivkavitqnidmlhqragsrrvlelhgs
mdkldcldchetydwsefvedfnkgeiprcrkcgsyyvkprvvlfgeplpqrtlfeaiee
akhcdafmvvgsslvvypaaelpyiakkagakmiivnaeptmadpifdvkiigkagevlp
kiveevkrlrsek

    Sequence, based on observed residues (ATOM records): (download) 
    >1s7gE (E:)
medeirkaaeilakskhavvftgagisaesgiptfrgedglwrkydpeevasisgfkrnp
rafwefsmemkdfaepnpahyaiaelermgivkavitqnidmlhqragsrrvlelhgsmd
kldcldchetydwsefvedfnkgeiprcrkcgsyyvkprvvlfgeplpqrtlfeaieeak
hcdafmvvgsslvvypaaelpyiakkagakmiivnaeptmadpifdvkiigkagevlpki
veevkrlr