PDB entry 1s65

View 1s65 on RCSB PDB site
Description: Crystal Structure Analysis of HIV-1 Protease Mutant V82A with a Potent Non-peptide Inhibitor (UIC-94017)
Class: hydrolase
Keywords: hiv-1 protease, mutant, dimer, inhibitor, uic-94017
Deposited on 2004-01-22, released 2004-06-22
The last revision prior to the SCOPe 2.07 freeze date was dated 2006-10-03, with a file datestamp of 2007-06-01.
Experiment type: XRAY
Resolution: 1.1 Å
R-factor: 0.117
AEROSPACI score: 0.94 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: Protease
  Species: Human immunodeficiency virus type 1
  Gene: pol
  Database cross-references and differences (RAF-indexed):
  • Uniprot P03368 (0-98)
    • engineered (6)
    • engineered (32)
    • engineered (62)
    • engineered (66)
    • engineered (81)
    • engineered (94)
  Domains in SCOPe 2.07: d1s65a_
• Chain 'B':
  Compound: Protease
  Species: Human immunodeficiency virus type 1
  Gene: pol
  Database cross-references and differences (RAF-indexed):
  • Uniprot P03368 (0-98)
    • engineered (6)
    • engineered (32)
    • engineered (62)
    • engineered (66)
    • engineered (81)
    • engineered (94)
  Domains in SCOPe 2.07: d1s65b_
• Heterogens: CL, PO4, 017, DMS, ACY, GOL, HOH

PDB Chain Sequences:

• Chain 'A':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >1s65A (A:)
  pqitlwkrplvtikiggqlkealldtgaddtvieemslpgrwkpkmiggiggfikvrqyd
  qiiieiaghkaigtvlvgptpaniigrnlltqigatlnf
  

  
  
• Chain 'B':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >1s65B (B:)
  pqitlwkrplvtikiggqlkealldtgaddtvieemslpgrwkpkmiggiggfikvrqyd
  qiiieiaghkaigtvlvgptpaniigrnlltqigatlnf