PDB entry 1s5c

View 1s5c on RCSB PDB site
Description: Cholera holotoxin with an A-subunit Y30S mutation, Crystal form 1
Class: transferase,toxin
Keywords: cholera toxin, heat-labile enterotoxin, ADP ribose transferases, AB5 toxins, TRANSFERASE,TOXIN
Deposited on 2004-01-20, released 2004-04-06
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.199
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Cholera enterotoxin, A chain
    Species: Vibrio cholerae [TaxId:666]
    Gene: CTXA, TOXA, VC1457
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1s5ca_
  • Chain 'D':
    Compound: cholera enterotoxin B-subunit
    Species: Vibrio cholerae [TaxId:666]
    Gene: CTXB, TOXB, VC1456
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1s5cd_
  • Chain 'E':
    Compound: cholera enterotoxin B-subunit
    Species: Vibrio cholerae [TaxId:666]
    Gene: CTXB, TOXB, VC1456
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1s5ce_
  • Chain 'F':
    Compound: cholera enterotoxin B-subunit
    Species: Vibrio cholerae [TaxId:666]
    Gene: CTXB, TOXB, VC1456
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1s5cf_
  • Chain 'G':
    Compound: cholera enterotoxin B-subunit
    Species: Vibrio cholerae [TaxId:666]
    Gene: CTXB, TOXB, VC1456
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1s5cg_
  • Chain 'H':
    Compound: cholera enterotoxin B-subunit
    Species: Vibrio cholerae [TaxId:666]
    Gene: CTXB, TOXB, VC1456
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1s5ch_
  • Heterogens: NA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1s5cA (A:)
nddklyradsrppdeikqsgglmprgqsesfdrgtqmninlydhargtqtgfvrhddgyv
stsislrsahlvgqtilsghstyyiyviatapnmfnvndvlgaysphpdeqevsalggip
ysqiygwyrvhfgvldeqlhrnrgyrdryysnldiapaadgyglagfppehrawreepwi
hhappgcgnaprssmsntcdektqslgvkfldeyqskvkrqifsgyqsdidthnrikdel

    Sequence, based on observed residues (ATOM records): (download) 
    >1s5cA (A:)
nddklyradsrppdeikqsgglmprmninlydhargtqgfvrhddgyvstsislrsahlv
gqtilsghstyyiyviatapnmfnvndvlgaysphpdeqevsalggipysqiygwyrvhf
gvldeqlhrnrgyrdryysnldiapaadgyglagfppehrawreepwihhappgcgnsnt
cdektqslgvkfldeyqskvkrqifsgyqsdidthn

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1s5cD (D:)
tpqnitdlcaeyhntqihtlndkifsyteslagkremaiitfkngatfqvevpgsqhids
qkkaiermkdtlriaylteakveklcvwnnktphaiaaisman

  • Chain 'E':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1s5cE (E:)
tpqnitdlcaeyhntqihtlndkifsyteslagkremaiitfkngatfqvevpgsqhids
qkkaiermkdtlriaylteakveklcvwnnktphaiaaisman

  • Chain 'F':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1s5cF (F:)
tpqnitdlcaeyhntqihtlndkifsyteslagkremaiitfkngatfqvevpgsqhids
qkkaiermkdtlriaylteakveklcvwnnktphaiaaisman

  • Chain 'G':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1s5cG (G:)
tpqnitdlcaeyhntqihtlndkifsyteslagkremaiitfkngatfqvevpgsqhids
qkkaiermkdtlriaylteakveklcvwnnktphaiaaisman

  • Chain 'H':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1s5cH (H:)
tpqnitdlcaeyhntqihtlndkifsyteslagkremaiitfkngatfqvevpgsqhids
qkkaiermkdtlriaylteakveklcvwnnktphaiaaisman