PDB entry 1s4y

View 1s4y on RCSB PDB site
Description: Crystal structure of the activin/actrIIb extracellular domain
Class: transferase
Keywords: structural genomics, JCSG, transferase, PSI, Protein Structure Initiative, Joint Center for Structural Genomics
Deposited on 2004-01-19, released 2004-08-10
The last revision prior to the SCOPe 2.06 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.21
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Activin receptor type IIB precursor
    Species: Mus musculus [TaxId:10090]
    Gene: Acvr2b
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d1s4ya_
  • Chain 'B':
    Compound: Inhibin beta A chain
    Species: Homo sapiens [TaxId:9606]
    Gene: INHBA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d1s4yb_
  • Chain 'C':
    Compound: Activin receptor type IIB precursor
    Species: Mus musculus [TaxId:10090]
    Gene: Acvr2b
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d1s4yc_
  • Chain 'D':
    Compound: Inhibin beta A chain
    Species: Homo sapiens [TaxId:9606]
    Gene: INHBA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d1s4yd_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1s4yA (A:)
eaetreciyynanwelertnqsglercegeqdkrlhcyaswrnssgtielvkkgcwlddf
ncydrqecvateenpqvyfcccegnfcnerfthlpepg

    Sequence, based on observed residues (ATOM records): (download) 
    >1s4yA (A:)
reciyynanwelertnqsglercegeqdkrlhcyaswrnssgtielvkkgcwlddfncyd
rqecvateenpqvyfcccegnfcnerfthlp

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1s4yB (B:)
glecdgkvnicckkqffvsfkdigwndwiiapsgyhanycegecpshiagtsgsslsfhs
tvinhyrmrghspfanlksccvptklrpmsmlyyddgqniikkdiqnmiveecgcs

    Sequence, based on observed residues (ATOM records): (download) 
    >1s4yB (B:)
glecdvnicckkqffvsfkdigwndwiiapsgyhanycegecpshiagtsgsslsfhstv
inhyrmrpfanlksccvptklrpmsmlyyddgqniikkdiqnmiveecgcs

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1s4yC (C:)
eaetreciyynanwelertnqsglercegeqdkrlhcyaswrnssgtielvkkgcwlddf
ncydrqecvateenpqvyfcccegnfcnerfthlpepg

    Sequence, based on observed residues (ATOM records): (download) 
    >1s4yC (C:)
treciyynanwelertnqsglercegeqdkrlhcyaswrnssgtielvkkgcwlddfncy
drqecvateenpqvyfcccegnfcnerfthlpepg

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1s4yD (D:)
glecdgkvnicckkqffvsfkdigwndwiiapsgyhanycegecpshiagtsgsslsfhs
tvinhyrmrghspfanlksccvptklrpmsmlyyddgqniikkdiqnmiveecgcs

    Sequence, based on observed residues (ATOM records): (download) 
    >1s4yD (D:)
cdgkvnicckkqffvsfkdigwndwiiapsgyhanycegecpshiafhstvinhyrmrgc
cvptklrpmsmlyyddgqniikkdiqnmiveecgcs