PDB entry 1s49

View 1s49 on RCSB PDB site
Description: Crystal Structure of RNA-dependent RNA polymerase construct 1 (residues 71-679) from bovine viral diarrhea virus complexed with GTP
Class: replication, RNA binding protein
Keywords: polymerase, RNA synthesis, de novo initiation, primer independent initiation, GTP binding, bovine viral diarrhea virus, BVDV, REPLICATION, RNA BINDING PROTEIN
Deposited on 2004-01-15, released 2004-04-06
The last revision prior to the SCOPe 2.07 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 3 Å
R-factor: 0.264
AEROSPACI score: 0.18 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: RNA-dependent RNA polymerase
    Species: Bovine viral diarrhea virus 1 [TaxId:11099]
    Gene: NS5B
    Database cross-references and differences (RAF-indexed):
    • Uniprot P19711 (Start-608)
      • modified residue (44)
      • modified residue (72)
      • modified residue (231)
      • modified residue (313)
      • modified residue (345)
      • modified residue (351-352)
      • modified residue (396)
      • modified residue (414)
      • modified residue (443)
      • modified residue (455)
      • modified residue (481)
    Domains in SCOPe 2.07: d1s49a_
  • Heterogens: GTP

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1s49A (A:)
aylklkdfieeeekkprvkdtvirehnkwilkkirfqgnlntkkmlnpgklseqldregr
krniynhqigtimssagirleklpivraqtdtktfheairdkidksenrqnpelhnklle
ifhtiaqptlkhtygevtweqleagvnrkgaagflekknigevldsekhlveqlvrdlka
grkikyyetaipknekrdvsddwqagdlvvekrprviqypeaktrlaitkvmynwvkqqp
vvipgyegktplfnifdkvrkewdsfnepvavsfdtkawdtqvtskdlqligeiqkyyyk
kewhkfidtitdhmtevpvitadgevyirngqrgsgqpdtsagnsmlnvltmmyafcest
gvpyksfnrvarihvcgddgflitekglglkfankgmqilheagkpqkitegekmkvayr
fediefcshtpvpvrwsdntsshmagrdtavilskmatrldssgergttayekavafsfl
lmyswnplvrricllvlsqqpetdpskhatyyykgdpigaykdvigrnlselkrtgfekl
anlnlslstlgvwtkhtskriiqdcvaigkeegnwlvkpdrlissktghlyipdkgftlq
gkhyeqlql

    Sequence, based on observed residues (ATOM records): (download) 
    >1s49A (A:)
virehnkwilkkirfqgnlntkkmlnpgklseqldregrkrniynhqigtimssagirle
klpivraqtdtktfheairdkidksenrqnpelhnklleifhtiaqptlkhtygevtweq
leagvnrkgaagflekknigevldsekhlveqlvrdlkagrkikyyetaipknekrdvsd
dwqagdlvvekrprviqypeaktrlaitkvmynwvkqqpvvipgyegktplfnifdkvrk
ewdsfnepvavsfdtkawdtqvtskdlqligeiqkyyykkewhkfidtitdhmtevpvit
adgevyirngqrgsgqpdtsagnsmlnvltmmyafcestgvpyksfnrvarihvcgddgf
litekglglkfankgmqilheagkpqkitegekmkvayrfediefcshtpvpvrwsdnts
shmagrdtavilskmatrldssgergttayekavafsfllmyswnplvrricllvlsqqp
etdpskhatyyykgdpigaykdvigrnlselkrtgfeklanlnlslstlgvwtkhtskri
iqdcvaigkeegnwlvkpdrlissktghlyipdkgftlqgkhyeqlql