PDB entry 1s17

View 1s17 on RCSB PDB site
Description: Identification of Novel Potent Bicyclic Peptide Deformylase Inhibitors
Class: hydrolase
Keywords: peptide deformylase inhibitor, rational drug design, antibiotic, protein-ligand complex, HYDROLASE
Deposited on 2004-01-05, released 2004-03-30
The last revision prior to the SCOPe 2.07 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-25.
Experiment type: XRAY
Resolution: 1.95 Å
R-factor: 0.196
AEROSPACI score: 0.47 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Peptide deformylase
    Species: Pseudomonas aeruginosa [TaxId:287]
    Gene: DEF, PA0019
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9I7A8
      • conflict (95)
    Domains in SCOPe 2.07: d1s17a_
  • Chain 'B':
    Compound: Peptide deformylase
    Species: Pseudomonas aeruginosa [TaxId:287]
    Gene: DEF, PA0019
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9I7A8
      • conflict (95)
    Domains in SCOPe 2.07: d1s17b_
  • Heterogens: NI, GNR, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1s17A (A:)
mgsdkihhhhhhmailnilefpdprlrtiakpvevvddavrqliddmfetmyeapgigla
atqvnvhkrivvmdlsedkseprvfinpefeplteemdqyqegclsvpgfyenvdrpqkv
rikaldrdgnpfeevaegllavciqhecdhlngklfvdylstlkrdrirkklekqhrqqa

    Sequence, based on observed residues (ATOM records): (download) 
    >1s17A (A:)
ailnilefpdprlrtiakpvevvddavrqliddmfetmyeapgiglaatqvnvhkrivvm
dlsedkseprvfinpefeplteemdqyqegclsvpgfyenvdrpqkvrikaldrdgnpfe
evaegllavciqhecdhlngklfvdylstlkrdrirkklekqhrqq

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1s17B (B:)
mgsdkihhhhhhmailnilefpdprlrtiakpvevvddavrqliddmfetmyeapgigla
atqvnvhkrivvmdlsedkseprvfinpefeplteemdqyqegclsvpgfyenvdrpqkv
rikaldrdgnpfeevaegllavciqhecdhlngklfvdylstlkrdrirkklekqhrqqa

    Sequence, based on observed residues (ATOM records): (download) 
    >1s17B (B:)
ailnilefpdprlrtiakpvevvddavrqliddmfetmyeapgiglaatqvnvhkrivvm
dlsedkseprvfinpefeplteemdqyqegclsvpgfyenvdrpqkvrikaldrdgnpfe
evaegllavciqhecdhlngklfvdylstlkrdrirkklekqhr