PDB entry 1rzf

View 1rzf on RCSB PDB site
Description: Crystal structure of Human anti-HIV-1 GP120-reactive antibody E51
Class: immune system
Keywords: HIV-1; gp120; CD4i; antibodies; tyrosine sulfation; VH-gene usage, IMMUNE SYSTEM
Deposited on 2003-12-24, released 2004-02-03
The last revision prior to the SCOPe 2.07 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-25.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: 0.198
AEROSPACI score: 0.54 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'H':
    Compound: Fab E51 heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 1RZF (Start-234)
    Domains in SCOPe 2.07: d1rzfh1, d1rzfh2
  • Chain 'L':
    Compound: Fab E51 light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 1RZF (0-212)
    Domains in SCOPe 2.07: d1rzfl1, d1rzfl2
  • Heterogens: GOL, IPA, HOH

PDB Chain Sequences:

  • Chain 'H':
    Sequence, based on SEQRES records: (download)
    >1rzfH (H:)
    evqlvqsgaevnkpgssvkvscqasgatlnshafswvrqapgqglewmagiipifgsshy
    aqkfrgrvtisadestrtvylhlrglrsddtavyycasnsiagvaaagdyadydggyyyd
    mdvwgqgttvtvssastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgal
    tsgvhtfpavlqssglyslssvvtvpssslgtqtyicnvnhkpsntkvdkrvepk
    

    Sequence, based on observed residues (ATOM records): (download)
    >1rzfH (H:)
    vqlvqsgaevnkpgssvkvscqasgatlnshafswvrqapgqglewmagiipifgsshya
    qkfrgrvtisadestrtvylhlrglrsddtavyycasnsiaggyyydmdvwgqgttvtvs
    sastkgpsvfplaptsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssgly
    slssvvtvpssslgtqtyicnvnhkpsntkvdkrvepk
    

  • Chain 'L':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1rzfL (L:)
    qsiltqppsvsaapgqkvtiscsgsssnignndvswyqqfpgtvpklviyennerpsgip
    drfsgsksgtsatlgitglqtgdeadyycgtwdsslsavvfgggskvtvlgqpkaapsvt
    lfppsseelqankatlvclisdfypgavtvawkadsspvkagvetttpskqsnnkyaass
    ylsltpeqwkshrsyscqvthegstvektvapt