PDB entry 1ryy

View 1ryy on RCSB PDB site
Description: Acetobacter turbidans alpha-amino acid ester hydrolase Y206A mutant
Class: hydrolase
Keywords: alpha/beta hydrolase fold, jellyroll fold, HYDROLASE
Deposited on 2003-12-23, released 2005-02-22
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: 0.211
AEROSPACI score: 0.25 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: alpha-amino acid ester hydrolase
    Species: Acetobacter pasteurianus [TaxId:438]
    Gene: aehA
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8VRK8
      • engineered (165)
    Domains in SCOPe 2.08: d1ryya1, d1ryya2
  • Chain 'B':
    Compound: alpha-amino acid ester hydrolase
    Species: Acetobacter pasteurianus [TaxId:438]
    Gene: aehA
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8VRK8
      • engineered (165)
    Domains in SCOPe 2.08: d1ryyb1, d1ryyb2
  • Chain 'C':
    Compound: alpha-amino acid ester hydrolase
    Species: Acetobacter pasteurianus [TaxId:438]
    Gene: aehA
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8VRK8
      • engineered (165)
    Domains in SCOPe 2.08: d1ryyc1, d1ryyc2
  • Chain 'D':
    Compound: alpha-amino acid ester hydrolase
    Species: Acetobacter pasteurianus [TaxId:438]
    Gene: aehA
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8VRK8
      • engineered (165)
    Domains in SCOPe 2.08: d1ryyd1, d1ryyd2
  • Chain 'E':
    Compound: alpha-amino acid ester hydrolase
    Species: Acetobacter pasteurianus [TaxId:438]
    Gene: aehA
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8VRK8
      • engineered (165)
    Domains in SCOPe 2.08: d1ryye1, d1ryye2
  • Chain 'F':
    Compound: alpha-amino acid ester hydrolase
    Species: Acetobacter pasteurianus [TaxId:438]
    Gene: aehA
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8VRK8
      • engineered (165)
    Domains in SCOPe 2.08: d1ryyf1, d1ryyf2
  • Chain 'G':
    Compound: alpha-amino acid ester hydrolase
    Species: Acetobacter pasteurianus [TaxId:438]
    Gene: aehA
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8VRK8
      • engineered (165)
    Domains in SCOPe 2.08: d1ryyg1, d1ryyg2
  • Chain 'H':
    Compound: alpha-amino acid ester hydrolase
    Species: Acetobacter pasteurianus [TaxId:438]
    Gene: aehA
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8VRK8
      • engineered (165)
    Domains in SCOPe 2.08: d1ryyh1, d1ryyh2
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1ryyA (A:)
apaadaaqahdplsvqtgsdipasvhmptdqqrdyikrevmvpmrdgvklytvivipkna
rnapilltrtpynakgranrvpnaltmrevlpqgddvfveggyirvfqdirgkygsqgdy
vmtrpphgplnptktdettdawdtvdwlvhnvpesngrvgmtgssaegftvvmalldphp
alkvaapespmvdgwmgddwfhygafrqgafdyfvsqmtargggndiprrdaddytnflk
agsagsfatqagldqypfwqrmhahpaydafwqgqaldkilaqrkptvpmlweqglwdqe
dmwgaihawqalkdadvkapntlvmgpwrhsgvnyngstlgplefegdtahqyrrdvfrp
ffdeylkpgsasvhlpdaiiyntgdqkwdyyrswpsvcesnctggltplyladghglsft
hpaadgadsyvsdpahpvpfisrpfafaqssrwkpwlvqdqreaesrpdvvtyetevlde
pvrvsgvpvadlfaatsgtdsdwvvklidvqpamtpddpkmggyelpvsmdifrgryrkd
fakpealqpdatlhyhftlpavnhvfakghrimvqiqsswfplydrnpqkfvpnifdakp
adytvatqsihhggkeatsillpvvkqklgpeqkliseedlnsavdhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >1ryyA (A:)
hdplsvqtgsdipasvqqrdyikrevmvpmrdgvklytvivipknarnapilltrtpyna
kgranrvpnaltmrevlpqgddvfveggyirvfqdirgkygsqgdyvmtrpphgplnptk
tdettdawdtvdwlvhnvpesngrvgmtgssaegftvvmalldphpalkvaapespmvdg
wmgddwfhygafrqgafdyfvsqmtargggndiprrdaddytnflkagsagsfatqagld
qypfwqrmhahpaydafwqgqaldkilaqrkptvpmlweqglwdqedmwgaihawqalkd
advkapntlvmgpwrhsgvnyngstlgplefegdtahqyrrdvfrpffdeylkpgsasvh
lpdaiiyntgdqkwdyyrswpsvcesnctggltplyladghglsfthpaadgadsyvsdp
ahpvpfisrpfafaqssrwkpwlvqdqreaesrpdvvtyetevldepvrvsgvpvadlfa
atsgtdsdwvvklidvqpamtpddpkmggyelpvsmdifrgryrkdfakpealqpdatlh
yhftlpavnhvfakghrimvqiqsswfplydrnpqkfvpnifdakpadytvatqsihhgg
keatsillpvvk

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1ryyB (B:)
apaadaaqahdplsvqtgsdipasvhmptdqqrdyikrevmvpmrdgvklytvivipkna
rnapilltrtpynakgranrvpnaltmrevlpqgddvfveggyirvfqdirgkygsqgdy
vmtrpphgplnptktdettdawdtvdwlvhnvpesngrvgmtgssaegftvvmalldphp
alkvaapespmvdgwmgddwfhygafrqgafdyfvsqmtargggndiprrdaddytnflk
agsagsfatqagldqypfwqrmhahpaydafwqgqaldkilaqrkptvpmlweqglwdqe
dmwgaihawqalkdadvkapntlvmgpwrhsgvnyngstlgplefegdtahqyrrdvfrp
ffdeylkpgsasvhlpdaiiyntgdqkwdyyrswpsvcesnctggltplyladghglsft
hpaadgadsyvsdpahpvpfisrpfafaqssrwkpwlvqdqreaesrpdvvtyetevlde
pvrvsgvpvadlfaatsgtdsdwvvklidvqpamtpddpkmggyelpvsmdifrgryrkd
fakpealqpdatlhyhftlpavnhvfakghrimvqiqsswfplydrnpqkfvpnifdakp
adytvatqsihhggkeatsillpvvkqklgpeqkliseedlnsavdhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >1ryyB (B:)
hdplsvqtgsdipasvqqrdyikrevmvpmrdgvklytvivipknarnapilltrtpyna
kgranrvpnaltmrevlpqgddvfveggyirvfqdirgkygsqgdyvmtrpphgplnptk
tdettdawdtvdwlvhnvpesngrvgmtgssaegftvvmalldphpalkvaapespmvdg
wmgddwfhygafrqgafdyfvsqmtargggndiprrdaddytnflkagsagsfatqagld
qypfwqrmhahpaydafwqgqaldkilaqrkptvpmlweqglwdqedmwgaihawqalkd
advkapntlvmgpwrhsgvnyngstlgplefegdtahqyrrdvfrpffdeylkpgsasvh
lpdaiiyntgdqkwdyyrswpsvcesnctggltplyladghglsfthpaadgadsyvsdp
ahpvpfisrpfafaqssrwkpwlvqdqreaesrpdvvtyetevldepvrvsgvpvadlfa
atsgtdsdwvvklidvqpamtpddpkmggyelpvsmdifrgryrkdfakpealqpdatlh
yhftlpavnhvfakghrimvqiqsswfplydrnpqkfvpnifdakpadytvatqsihhgg
keatsillpvvk

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1ryyC (C:)
apaadaaqahdplsvqtgsdipasvhmptdqqrdyikrevmvpmrdgvklytvivipkna
rnapilltrtpynakgranrvpnaltmrevlpqgddvfveggyirvfqdirgkygsqgdy
vmtrpphgplnptktdettdawdtvdwlvhnvpesngrvgmtgssaegftvvmalldphp
alkvaapespmvdgwmgddwfhygafrqgafdyfvsqmtargggndiprrdaddytnflk
agsagsfatqagldqypfwqrmhahpaydafwqgqaldkilaqrkptvpmlweqglwdqe
dmwgaihawqalkdadvkapntlvmgpwrhsgvnyngstlgplefegdtahqyrrdvfrp
ffdeylkpgsasvhlpdaiiyntgdqkwdyyrswpsvcesnctggltplyladghglsft
hpaadgadsyvsdpahpvpfisrpfafaqssrwkpwlvqdqreaesrpdvvtyetevlde
pvrvsgvpvadlfaatsgtdsdwvvklidvqpamtpddpkmggyelpvsmdifrgryrkd
fakpealqpdatlhyhftlpavnhvfakghrimvqiqsswfplydrnpqkfvpnifdakp
adytvatqsihhggkeatsillpvvkqklgpeqkliseedlnsavdhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >1ryyC (C:)
hdplsvqtgsdipasvqqrdyikrevmvpmrdgvklytvivipknarnapilltrtpyna
kgranrvpnaltmrevlpqgddvfveggyirvfqdirgkygsqgdyvmtrpphgplnptk
tdettdawdtvdwlvhnvpesngrvgmtgssaegftvvmalldphpalkvaapespmvdg
wmgddwfhygafrqgafdyfvsqmtargggndiprrdaddytnflkagsagsfatqagld
qypfwqrmhahpaydafwqgqaldkilaqrkptvpmlweqglwdqedmwgaihawqalkd
advkapntlvmgpwrhsgvnyngstlgplefegdtahqyrrdvfrpffdeylkpgsasvh
lpdaiiyntgdqkwdyyrswpsvcesnctggltplyladghglsfthpaadgadsyvsdp
ahpvpfisrpfafaqssrwkpwlvqdqreaesrpdvvtyetevldepvrvsgvpvadlfa
atsgtdsdwvvklidvqpamtpddpkmggyelpvsmdifrgryrkdfakpealqpdatlh
yhftlpavnhvfakghrimvqiqsswfplydrnpqkfvpnifdakpadytvatqsihhgg
keatsillpvvk

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1ryyD (D:)
apaadaaqahdplsvqtgsdipasvhmptdqqrdyikrevmvpmrdgvklytvivipkna
rnapilltrtpynakgranrvpnaltmrevlpqgddvfveggyirvfqdirgkygsqgdy
vmtrpphgplnptktdettdawdtvdwlvhnvpesngrvgmtgssaegftvvmalldphp
alkvaapespmvdgwmgddwfhygafrqgafdyfvsqmtargggndiprrdaddytnflk
agsagsfatqagldqypfwqrmhahpaydafwqgqaldkilaqrkptvpmlweqglwdqe
dmwgaihawqalkdadvkapntlvmgpwrhsgvnyngstlgplefegdtahqyrrdvfrp
ffdeylkpgsasvhlpdaiiyntgdqkwdyyrswpsvcesnctggltplyladghglsft
hpaadgadsyvsdpahpvpfisrpfafaqssrwkpwlvqdqreaesrpdvvtyetevlde
pvrvsgvpvadlfaatsgtdsdwvvklidvqpamtpddpkmggyelpvsmdifrgryrkd
fakpealqpdatlhyhftlpavnhvfakghrimvqiqsswfplydrnpqkfvpnifdakp
adytvatqsihhggkeatsillpvvkqklgpeqkliseedlnsavdhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >1ryyD (D:)
hdplsvqtgsdipasvqqrdyikrevmvpmrdgvklytvivipknarnapilltrtpyna
kgranrvpnaltmrevlpqgddvfveggyirvfqdirgkygsqgdyvmtrpphgplnptk
tdettdawdtvdwlvhnvpesngrvgmtgssaegftvvmalldphpalkvaapespmvdg
wmgddwfhygafrqgafdyfvsqmtargggndiprrdaddytnflkagsagsfatqagld
qypfwqrmhahpaydafwqgqaldkilaqrkptvpmlweqglwdqedmwgaihawqalkd
advkapntlvmgpwrhsgvnyngstlgplefegdtahqyrrdvfrpffdeylkpgsasvh
lpdaiiyntgdqkwdyyrswpsvcesnctggltplyladghglsfthpaadgadsyvsdp
ahpvpfisrpfafaqssrwkpwlvqdqreaesrpdvvtyetevldepvrvsgvpvadlfa
atsgtdsdwvvklidvqpamtpddpkmggyelpvsmdifrgryrkdfakpealqpdatlh
yhftlpavnhvfakghrimvqiqsswfplydrnpqkfvpnifdakpadytvatqsihhgg
keatsillpvvk

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >1ryyE (E:)
apaadaaqahdplsvqtgsdipasvhmptdqqrdyikrevmvpmrdgvklytvivipkna
rnapilltrtpynakgranrvpnaltmrevlpqgddvfveggyirvfqdirgkygsqgdy
vmtrpphgplnptktdettdawdtvdwlvhnvpesngrvgmtgssaegftvvmalldphp
alkvaapespmvdgwmgddwfhygafrqgafdyfvsqmtargggndiprrdaddytnflk
agsagsfatqagldqypfwqrmhahpaydafwqgqaldkilaqrkptvpmlweqglwdqe
dmwgaihawqalkdadvkapntlvmgpwrhsgvnyngstlgplefegdtahqyrrdvfrp
ffdeylkpgsasvhlpdaiiyntgdqkwdyyrswpsvcesnctggltplyladghglsft
hpaadgadsyvsdpahpvpfisrpfafaqssrwkpwlvqdqreaesrpdvvtyetevlde
pvrvsgvpvadlfaatsgtdsdwvvklidvqpamtpddpkmggyelpvsmdifrgryrkd
fakpealqpdatlhyhftlpavnhvfakghrimvqiqsswfplydrnpqkfvpnifdakp
adytvatqsihhggkeatsillpvvkqklgpeqkliseedlnsavdhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >1ryyE (E:)
hdplsvqtgsdipasvqqrdyikrevmvpmrdgvklytvivipknarnapilltrtpyna
kgranrvpnaltmrevlpqgddvfveggyirvfqdirgkygsqgdyvmtrpphgplnptk
tdettdawdtvdwlvhnvpesngrvgmtgssaegftvvmalldphpalkvaapespmvdg
wmgddwfhygafrqgafdyfvsqmtargggndiprrdaddytnflkagsagsfatqagld
qypfwqrmhahpaydafwqgqaldkilaqrkptvpmlweqglwdqedmwgaihawqalkd
advkapntlvmgpwrhsgvnyngstlgplefegdtahqyrrdvfrpffdeylkpgsasvh
lpdaiiyntgdqkwdyyrswpsvcesnctggltplyladghglsfthpaadgadsyvsdp
ahpvpfisrpfafaqssrwkpwlvqdqreaesrpdvvtyetevldepvrvsgvpvadlfa
atsgtdsdwvvklidvqpamtpddpkmggyelpvsmdifrgryrkdfakpealqpdatlh
yhftlpavnhvfakghrimvqiqsswfplydrnpqkfvpnifdakpadytvatqsihhgg
keatsillpvvk

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >1ryyF (F:)
apaadaaqahdplsvqtgsdipasvhmptdqqrdyikrevmvpmrdgvklytvivipkna
rnapilltrtpynakgranrvpnaltmrevlpqgddvfveggyirvfqdirgkygsqgdy
vmtrpphgplnptktdettdawdtvdwlvhnvpesngrvgmtgssaegftvvmalldphp
alkvaapespmvdgwmgddwfhygafrqgafdyfvsqmtargggndiprrdaddytnflk
agsagsfatqagldqypfwqrmhahpaydafwqgqaldkilaqrkptvpmlweqglwdqe
dmwgaihawqalkdadvkapntlvmgpwrhsgvnyngstlgplefegdtahqyrrdvfrp
ffdeylkpgsasvhlpdaiiyntgdqkwdyyrswpsvcesnctggltplyladghglsft
hpaadgadsyvsdpahpvpfisrpfafaqssrwkpwlvqdqreaesrpdvvtyetevlde
pvrvsgvpvadlfaatsgtdsdwvvklidvqpamtpddpkmggyelpvsmdifrgryrkd
fakpealqpdatlhyhftlpavnhvfakghrimvqiqsswfplydrnpqkfvpnifdakp
adytvatqsihhggkeatsillpvvkqklgpeqkliseedlnsavdhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >1ryyF (F:)
hdplsvqtgsdipasvqqrdyikrevmvpmrdgvklytvivipknarnapilltrtpyna
kgranrvpnaltmrevlpqgddvfveggyirvfqdirgkygsqgdyvmtrpphgplnptk
tdettdawdtvdwlvhnvpesngrvgmtgssaegftvvmalldphpalkvaapespmvdg
wmgddwfhygafrqgafdyfvsqmtargggndiprrdaddytnflkagsagsfatqagld
qypfwqrmhahpaydafwqgqaldkilaqrkptvpmlweqglwdqedmwgaihawqalkd
advkapntlvmgpwrhsgvnyngstlgplefegdtahqyrrdvfrpffdeylkpgsasvh
lpdaiiyntgdqkwdyyrswpsvcesnctggltplyladghglsfthpaadgadsyvsdp
ahpvpfisrpfafaqssrwkpwlvqdqreaesrpdvvtyetevldepvrvsgvpvadlfa
atsgtdsdwvvklidvqpamtpddpkmggyelpvsmdifrgryrkdfakpealqpdatlh
yhftlpavnhvfakghrimvqiqsswfplydrnpqkfvpnifdakpadytvatqsihhgg
keatsillpvvk

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >1ryyG (G:)
apaadaaqahdplsvqtgsdipasvhmptdqqrdyikrevmvpmrdgvklytvivipkna
rnapilltrtpynakgranrvpnaltmrevlpqgddvfveggyirvfqdirgkygsqgdy
vmtrpphgplnptktdettdawdtvdwlvhnvpesngrvgmtgssaegftvvmalldphp
alkvaapespmvdgwmgddwfhygafrqgafdyfvsqmtargggndiprrdaddytnflk
agsagsfatqagldqypfwqrmhahpaydafwqgqaldkilaqrkptvpmlweqglwdqe
dmwgaihawqalkdadvkapntlvmgpwrhsgvnyngstlgplefegdtahqyrrdvfrp
ffdeylkpgsasvhlpdaiiyntgdqkwdyyrswpsvcesnctggltplyladghglsft
hpaadgadsyvsdpahpvpfisrpfafaqssrwkpwlvqdqreaesrpdvvtyetevlde
pvrvsgvpvadlfaatsgtdsdwvvklidvqpamtpddpkmggyelpvsmdifrgryrkd
fakpealqpdatlhyhftlpavnhvfakghrimvqiqsswfplydrnpqkfvpnifdakp
adytvatqsihhggkeatsillpvvkqklgpeqkliseedlnsavdhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >1ryyG (G:)
hdplsvqtgsdipasvqqrdyikrevmvpmrdgvklytvivipknarnapilltrtpyna
kgranrvpnaltmrevlpqgddvfveggyirvfqdirgkygsqgdyvmtrpphgplnptk
tdettdawdtvdwlvhnvpesngrvgmtgssaegftvvmalldphpalkvaapespmvdg
wmgddwfhygafrqgafdyfvsqmtargggndiprrdaddytnflkagsagsfatqagld
qypfwqrmhahpaydafwqgqaldkilaqrkptvpmlweqglwdqedmwgaihawqalkd
advkapntlvmgpwrhsgvnyngstlgplefegdtahqyrrdvfrpffdeylkpgsasvh
lpdaiiyntgdqkwdyyrswpsvcesnctggltplyladghglsfthpaadgadsyvsdp
ahpvpfisrpfafaqssrwkpwlvqdqreaesrpdvvtyetevldepvrvsgvpvadlfa
atsgtdsdwvvklidvqpamtpddpkmggyelpvsmdifrgryrkdfakpealqpdatlh
yhftlpavnhvfakghrimvqiqsswfplydrnpqkfvpnifdakpadytvatqsihhgg
keatsillpvvk

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >1ryyH (H:)
apaadaaqahdplsvqtgsdipasvhmptdqqrdyikrevmvpmrdgvklytvivipkna
rnapilltrtpynakgranrvpnaltmrevlpqgddvfveggyirvfqdirgkygsqgdy
vmtrpphgplnptktdettdawdtvdwlvhnvpesngrvgmtgssaegftvvmalldphp
alkvaapespmvdgwmgddwfhygafrqgafdyfvsqmtargggndiprrdaddytnflk
agsagsfatqagldqypfwqrmhahpaydafwqgqaldkilaqrkptvpmlweqglwdqe
dmwgaihawqalkdadvkapntlvmgpwrhsgvnyngstlgplefegdtahqyrrdvfrp
ffdeylkpgsasvhlpdaiiyntgdqkwdyyrswpsvcesnctggltplyladghglsft
hpaadgadsyvsdpahpvpfisrpfafaqssrwkpwlvqdqreaesrpdvvtyetevlde
pvrvsgvpvadlfaatsgtdsdwvvklidvqpamtpddpkmggyelpvsmdifrgryrkd
fakpealqpdatlhyhftlpavnhvfakghrimvqiqsswfplydrnpqkfvpnifdakp
adytvatqsihhggkeatsillpvvkqklgpeqkliseedlnsavdhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >1ryyH (H:)
hdplsvqtgsdipasvqqrdyikrevmvpmrdgvklytvivipknarnapilltrtpyna
kgranrvpnaltmrevlpqgddvfveggyirvfqdirgkygsqgdyvmtrpphgplnptk
tdettdawdtvdwlvhnvpesngrvgmtgssaegftvvmalldphpalkvaapespmvdg
wmgddwfhygafrqgafdyfvsqmtargggndiprrdaddytnflkagsagsfatqagld
qypfwqrmhahpaydafwqgqaldkilaqrkptvpmlweqglwdqedmwgaihawqalkd
advkapntlvmgpwrhsgvnyngstlgplefegdtahqyrrdvfrpffdeylkpgsasvh
lpdaiiyntgdqkwdyyrswpsvcesnctggltplyladghglsfthpaadgadsyvsdp
ahpvpfisrpfafaqssrwkpwlvqdqreaesrpdvvtyetevldepvrvsgvpvadlfa
atsgtdsdwvvklidvqpamtpddpkmggyelpvsmdifrgryrkdfakpealqpdatlh
yhftlpavnhvfakghrimvqiqsswfplydrnpqkfvpnifdakpadytvatqsihhgg
keatsillpvvk