PDB entry 1ryp

View 1ryp on RCSB PDB site
Description: crystal structure of the 20s proteasome from yeast at 2.4 angstroms resolution
Class: multicatalytic proteinase
Keywords: multicatalytic proteinase, 20s proteasome, protein degradation, antigen processing, hydrolase, protease
Deposited on 1997-02-26, released 1998-04-15
The last revision prior to the SCOP 1.75 freeze date was dated 1998-04-15, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: 0.286
AEROSPACI score: 0.41 (click here for full SPACI score report)

Chains and heterogens:

  • Chain '1':
    Compound: 20S proteasome
    Species: SACCHAROMYCES CEREVISIAE
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1ryp1_
  • Chain '2':
    Compound: 20S proteasome
    Species: SACCHAROMYCES CEREVISIAE
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1ryp2_
  • Chain 'A':
    Compound: 20S proteasome
    Species: SACCHAROMYCES CEREVISIAE
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1rypa_
  • Chain 'B':
    Compound: 20S proteasome
    Species: SACCHAROMYCES CEREVISIAE
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1rypb_
  • Chain 'C':
    Compound: 20S proteasome
    Species: SACCHAROMYCES CEREVISIAE
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1rypc_
  • Chain 'D':
    Compound: 20S proteasome
    Species: SACCHAROMYCES CEREVISIAE
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1rypd_
  • Chain 'E':
    Compound: 20S proteasome
    Species: SACCHAROMYCES CEREVISIAE
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1rype_
  • Chain 'F':
    Compound: 20S proteasome
    Species: SACCHAROMYCES CEREVISIAE
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1rypf_
  • Chain 'G':
    Compound: 20S proteasome
    Species: SACCHAROMYCES CEREVISIAE
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1rypg_
  • Chain 'H':
    Compound: 20S proteasome
    Species: SACCHAROMYCES CEREVISIAE
    Database cross-references and differences (RAF-indexed):
    • Uniprot P38624 (0-204)
      • conflict (9)
    Domains in SCOP 1.75: d1ryph_
  • Chain 'I':
    Compound: 20S proteasome
    Species: SACCHAROMYCES CEREVISIAE
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1rypi_
  • Chain 'J':
    Compound: 20S proteasome
    Species: SACCHAROMYCES CEREVISIAE
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1rypj_
  • Chain 'K':
    Compound: 20S proteasome
    Species: SACCHAROMYCES CEREVISIAE
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1rypk_
  • Chain 'L':
    Compound: 20S proteasome
    Species: SACCHAROMYCES CEREVISIAE
    Database cross-references and differences (RAF-indexed):
    • Uniprot P30656 (0-211)
      • conflict (32)
    Domains in SCOP 1.75: d1rypl_
  • Chain 'M':
    Compound: 20S proteasome
    Species: SACCHAROMYCES CEREVISIAE
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1rypm_
  • Chain 'N':
    Compound: 20S proteasome
    Species: SACCHAROMYCES CEREVISIAE
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1rypn_
  • Chain 'O':
    Compound: 20S proteasome
    Species: SACCHAROMYCES CEREVISIAE
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1rypo_
  • Chain 'P':
    Compound: 20S proteasome
    Species: SACCHAROMYCES CEREVISIAE
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1rypp_
  • Chain 'Q':
    Compound: 20S proteasome
    Species: SACCHAROMYCES CEREVISIAE
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1rypq_
  • Chain 'R':
    Compound: 20S proteasome
    Species: SACCHAROMYCES CEREVISIAE
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1rypr_
  • Chain 'S':
    Compound: 20S proteasome
    Species: SACCHAROMYCES CEREVISIAE
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1ryps_
  • Chain 'T':
    Compound: 20S proteasome
    Species: SACCHAROMYCES CEREVISIAE
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1rypt_
  • Chain 'U':
    Compound: 20S proteasome
    Species: SACCHAROMYCES CEREVISIAE
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1rypu_
  • Chain 'V':
    Compound: 20S proteasome
    Species: SACCHAROMYCES CEREVISIAE
    Database cross-references and differences (RAF-indexed):
    • Uniprot P38624 (0-204)
      • conflict (9)
    Domains in SCOP 1.75: d1rypv_
  • Chain 'W':
    Compound: 20S proteasome
    Species: SACCHAROMYCES CEREVISIAE
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1rypw_
  • Chain 'X':
    Compound: 20S proteasome
    Species: SACCHAROMYCES CEREVISIAE
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1rypx_
  • Chain 'Y':
    Compound: 20S proteasome
    Species: SACCHAROMYCES CEREVISIAE
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1rypy_
  • Chain 'Z':
    Compound: 20S proteasome
    Species: SACCHAROMYCES CEREVISIAE
    Database cross-references and differences (RAF-indexed):
    • Uniprot P30656 (0-211)
      • conflict (32)
    Domains in SCOP 1.75: d1rypz_
  • Heterogens: MG, HOH

PDB Chain Sequences:

  • Chain '1':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1ryp1 (1:)
qfnpygdnggtilgiagedfavlagdtrnitdysinsryepkvfdcgdnivmsangfaad
gdalvkrfknsvkwyhfdhndkklsinsaarniqhllygkrffpyyvhtiiagldedgkg
avysfdpvgsyereqcraggaaaslimpfldnqvnfknqyepgtngkvkkplkylsveev
iklvrdsftsaterhiqvgdgleilivtkdgvrkefyelkrd

  • Chain '2':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1ryp2 (2:)
tqqpivtgtsvismkydngviiaadnlgsygsllrfngverlipvgdntvvgisgdisdm
qhierllkdlvtenaydnpladaeealepsyifeylatvmyqrrskmnplwnaiivagvq
sngdqflryvnllgvtyssptlatgfgahmanpllrkvvdresdipkttvqvaeeaivna
mrvlyyrdarssrnfslaiidkntgltfkknlqvenmkwdfakdikgygtqki

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1rypA (A:)
agydrhitifspegrlyqveyafkatnqtninslavrgkdctvvisqkkvpdklldpttv
syifcisrtigmvvngpipdarnaalrakaeaaefrykygydmpcdvlakrmanlsqiyt
qraymrplgviltfvsvdeelgpsiyktdpagyyvgykatatgpkqqeittnlenhfkks
kidhineeswekvvefaithmidalgtefskndlevgvatkdkfftlsaenieerlvaia
eqd

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1rypB (B:)
mtdrysfslttfspsgklgqidyaltavkqgvtslgikatngvviatekksssplamset
lskvslltpdigavysgmgpdyrvlvdksrkvahtsykriygeypptkllvsevakimqe
atqsggvrpfgvslliaghdefngfslyqvdpsgsyfpwkataigkgsvaaktflekrwn
deleledaihialltlkesvegefngdtielaiigdenpdllgytgiptdkgprfrklts
qeindrleal

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1rypC (C:)
gsrrydsrttifspegrlyqveyalesishagtaigimasdgivlaaerkvtstlleqdt
steklyklndkiavavagltadaeilintarihaqnylktynedipveilvrrlsdikqg
ytqhgglrpfgvsfiyagyddrygyqlytsnpsgnytgwkaisvgantsaaqtllqmdyk
ddmkvddaielalktlskttdssaltydrlefatirkgandgevyqkifkpqeikdilvk
tgit

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1rypD (D:)
gydralsifspdghifqveyaleavkrgtcavgvkgkncvvlgcerrstlklqdtritps
kvskidshvvlsfsglnadsriliekarveaqshrltledpvtveyltryvagvqqrytq
sggvrpfgvstliagfdprddepklyqtepsgiysswsaqtigrnsktvrefleknydrk
eppatveecvkltvrsllevvqtgaknieitvvkpdsdivalsseeinqyvtqieqekqe
q

  • Chain 'E':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1rypE (E:)
drgvstfspegrlfqveysleaiklgstaigiatkegvvlgvekratspllesdsiekiv
eidrhigcamsgltadarsmiehartaavthnlyydedinvesltqsvcdlalrfgegas
geerlmsrpfgvalliaghdaddgyqlfhaepsgtfyrynakaigsgsegaqaellnewh
ssltlkeaellvlkilkqvmeekldennaqlscitkqdgfkiydnektaelikelkekea
ae

  • Chain 'F':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1rypF (F:)
frnnydgdtvtfsptgrlfqveyaleaikqgsvtvglrsnthavlvalkrnadelssyqk
kiikcdehmglslaglapdarvlsnylrqqcnysslvfnrklaveraghllcdkaqkntq
syggrpygvglliigydksgahllefqpsgnvtelygtaigarsqgaktylertldtfik
idgnpdelikagveaisqslrdesltvdnlsiaivgkdtpftiydgeavakyi

  • Chain 'G':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1rypG (G:)
gtgydlsnsvfspdgrnfqveyavkavengttsigikcndgvvfaveklitskllvpqkn
vkiqvvdrhigcvysglipdgrhlvnrgreeaasfkklyktpipipafadrlgqyvqaht
lynsvrpfgvstifggvdkngahlymlepsgsywgykgaatgkgrqsakaeleklvdhhp
eglsareavkqaakiiylahednkekdfeleiswcslsetnglhkfvkgdllqeaidfaq
kein

  • Chain 'H':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1rypH (H:)
lkkgevslgasimavtfkdgvilgadsrtttgayianrvtdkltrvhdkiwccrsgsaad
tqaiadivqyhlelytsqygtpstetaasvfkelcyenkdnltagiivagyddknkgevy
tiplggsvhklpyaiagsgstfiygycdknfrenmskeetvdfikhslsqaikwdgssgg
virmvvltaagverlifypdeyeql

  • Chain 'I':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1rypI (I:)
ttivgvkfnngvviaadtrstqgpivadkncaklhrispkiwcagagtaadteavtqlig
snielhslytsreprvvsalqmlkqhlfkyqghigaylivagvdptgshlfsihahgstd
vgyylslgsgslaamavleshwkqdltkeeaiklasdaiqagiwndlgsgsnvdvcvmei
gkdaeylrnyltpnvreekqksykfprgttavlkesivnicd

  • Chain 'J':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1rypJ (J:)
sdpssinggivvamtgkdcvaiacdlrlgsqslgvsnkfekifhyghvflgitglatdvt
tlnemfryktnlyklkeeraiepetftqlvssslyerrfgpyfvgpvvaginsksgkpfi
agfdligcideakdfivsgtasdqlfgmceslyepnlepedlfetisqallnaadrdals
gwgavvyiikkdevvkrylkmrqd

  • Chain 'K':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1rypK (K:)
mdiilgirvqdsvilasskavtrgisvlkdsddktrqlsphtlmsfageagdtvqfaeyi
qaniqlysiredyelspqavssfvrqelaksirsrrpyqvnvliggydkkknkpelyqid
ylgtkvelpygahgysgfytfslldhhyrpdmtteegldllklcvqelekrmpmdfkgvi
vkivdkdgirqvddfqaq

  • Chain 'L':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1rypL (L:)
tttlafrfqggiivavdsratagnwvasqtvkrvieinpfllgtmaggaadcqfwetwlg
sqcrlhelrekerisvaaaskilsnlvyqykgaglsmgtmicgytrkegptiyyvdsdgt
rlkgdifcvgsgqtfaygvldsnykwdlsvedalylgkrsilaaahrdaysggsvnlyhv
tedgwiyhgnhdvgelfwkvkeeegsfnnvig

  • Chain 'M':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1rypM (M:)
qfnpygdnggtilgiagedfavlagdtrnitdysinsryepkvfdcgdnivmsangfaad
gdalvkrfknsvkwyhfdhndkklsinsaarniqhllygkrffpyyvhtiiagldedgkg
avysfdpvgsyereqcraggaaaslimpfldnqvnfknqyepgtngkvkkplkylsveev
iklvrdsftsaterhiqvgdgleilivtkdgvrkefyelkrd

  • Chain 'N':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1rypN (N:)
tqqpivtgtsvismkydngviiaadnlgsygsllrfngverlipvgdntvvgisgdisdm
qhierllkdlvtenaydnpladaeealepsyifeylatvmyqrrskmnplwnaiivagvq
sngdqflryvnllgvtyssptlatgfgahmanpllrkvvdresdipkttvqvaeeaivna
mrvlyyrdarssrnfslaiidkntgltfkknlqvenmkwdfakdikgygtqki

  • Chain 'O':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1rypO (O:)
agydrhitifspegrlyqveyafkatnqtninslavrgkdctvvisqkkvpdklldpttv
syifcisrtigmvvngpipdarnaalrakaeaaefrykygydmpcdvlakrmanlsqiyt
qraymrplgviltfvsvdeelgpsiyktdpagyyvgykatatgpkqqeittnlenhfkks
kidhineeswekvvefaithmidalgtefskndlevgvatkdkfftlsaenieerlvaia
eqd

  • Chain 'P':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1rypP (P:)
mtdrysfslttfspsgklgqidyaltavkqgvtslgikatngvviatekksssplamset
lskvslltpdigavysgmgpdyrvlvdksrkvahtsykriygeypptkllvsevakimqe
atqsggvrpfgvslliaghdefngfslyqvdpsgsyfpwkataigkgsvaaktflekrwn
deleledaihialltlkesvegefngdtielaiigdenpdllgytgiptdkgprfrklts
qeindrleal

  • Chain 'Q':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1rypQ (Q:)
gsrrydsrttifspegrlyqveyalesishagtaigimasdgivlaaerkvtstlleqdt
steklyklndkiavavagltadaeilintarihaqnylktynedipveilvrrlsdikqg
ytqhgglrpfgvsfiyagyddrygyqlytsnpsgnytgwkaisvgantsaaqtllqmdyk
ddmkvddaielalktlskttdssaltydrlefatirkgandgevyqkifkpqeikdilvk
tgit

  • Chain 'R':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1rypR (R:)
gydralsifspdghifqveyaleavkrgtcavgvkgkncvvlgcerrstlklqdtritps
kvskidshvvlsfsglnadsriliekarveaqshrltledpvtveyltryvagvqqrytq
sggvrpfgvstliagfdprddepklyqtepsgiysswsaqtigrnsktvrefleknydrk
eppatveecvkltvrsllevvqtgaknieitvvkpdsdivalsseeinqyvtqieqekqe
q

  • Chain 'S':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1rypS (S:)
drgvstfspegrlfqveysleaiklgstaigiatkegvvlgvekratspllesdsiekiv
eidrhigcamsgltadarsmiehartaavthnlyydedinvesltqsvcdlalrfgegas
geerlmsrpfgvalliaghdaddgyqlfhaepsgtfyrynakaigsgsegaqaellnewh
ssltlkeaellvlkilkqvmeekldennaqlscitkqdgfkiydnektaelikelkekea
ae

  • Chain 'T':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1rypT (T:)
frnnydgdtvtfsptgrlfqveyaleaikqgsvtvglrsnthavlvalkrnadelssyqk
kiikcdehmglslaglapdarvlsnylrqqcnysslvfnrklaveraghllcdkaqkntq
syggrpygvglliigydksgahllefqpsgnvtelygtaigarsqgaktylertldtfik
idgnpdelikagveaisqslrdesltvdnlsiaivgkdtpftiydgeavakyi

  • Chain 'U':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1rypU (U:)
gtgydlsnsvfspdgrnfqveyavkavengttsigikcndgvvfaveklitskllvpqkn
vkiqvvdrhigcvysglipdgrhlvnrgreeaasfkklyktpipipafadrlgqyvqaht
lynsvrpfgvstifggvdkngahlymlepsgsywgykgaatgkgrqsakaeleklvdhhp
eglsareavkqaakiiylahednkekdfeleiswcslsetnglhkfvkgdllqeaidfaq
kein

  • Chain 'V':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1rypV (V:)
lkkgevslgasimavtfkdgvilgadsrtttgayianrvtdkltrvhdkiwccrsgsaad
tqaiadivqyhlelytsqygtpstetaasvfkelcyenkdnltagiivagyddknkgevy
tiplggsvhklpyaiagsgstfiygycdknfrenmskeetvdfikhslsqaikwdgssgg
virmvvltaagverlifypdeyeql

  • Chain 'W':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1rypW (W:)
ttivgvkfnngvviaadtrstqgpivadkncaklhrispkiwcagagtaadteavtqlig
snielhslytsreprvvsalqmlkqhlfkyqghigaylivagvdptgshlfsihahgstd
vgyylslgsgslaamavleshwkqdltkeeaiklasdaiqagiwndlgsgsnvdvcvmei
gkdaeylrnyltpnvreekqksykfprgttavlkesivnicd

  • Chain 'X':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1rypX (X:)
sdpssinggivvamtgkdcvaiacdlrlgsqslgvsnkfekifhyghvflgitglatdvt
tlnemfryktnlyklkeeraiepetftqlvssslyerrfgpyfvgpvvaginsksgkpfi
agfdligcideakdfivsgtasdqlfgmceslyepnlepedlfetisqallnaadrdals
gwgavvyiikkdevvkrylkmrqd

  • Chain 'Y':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1rypY (Y:)
mdiilgirvqdsvilasskavtrgisvlkdsddktrqlsphtlmsfageagdtvqfaeyi
qaniqlysiredyelspqavssfvrqelaksirsrrpyqvnvliggydkkknkpelyqid
ylgtkvelpygahgysgfytfslldhhyrpdmtteegldllklcvqelekrmpmdfkgvi
vkivdkdgirqvddfqaq

  • Chain 'Z':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1rypZ (Z:)
tttlafrfqggiivavdsratagnwvasqtvkrvieinpfllgtmaggaadcqfwetwlg
sqcrlhelrekerisvaaaskilsnlvyqykgaglsmgtmicgytrkegptiyyvdsdgt
rlkgdifcvgsgqtfaygvldsnykwdlsvedalylgkrsilaaahrdaysggsvnlyhv
tedgwiyhgnhdvgelfwkvkeeegsfnnvig