PDB entry 1rx5
View 1rx5 on RCSB PDB site
Description: dihydrofolate reductase (e.c.1.5.1.3) complexed with 5,10-dideazatetrahydrofolate
Class: oxidoreductase
Keywords: oxido-reductase, nadp, trimethoprim resistance, methotrexate resistance, one-carbon metabolism, oxidoreductase
Deposited on
1996-09-19, released
1997-01-11
The last revision prior to the SCOPe 2.08 freeze date was dated
2009-02-24, with a file datestamp of
2009-03-01.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.174
AEROSPACI score: 0.35
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: dihydrofolate reductase
Species: Escherichia coli [TaxId:562]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d1rx5a_ - Heterogens: DDF, HOH