PDB entry 1rx0

View 1rx0 on RCSB PDB site
Description: Crystal structure of isobutyryl-CoA dehydrogenase complexed with substrate/ligand.
Class: oxidoreductase
Keywords: flavoprotein, dehydrogenase, coenzyme A, OXIDOREDUCTASE
Deposited on 2003-12-18, released 2004-04-20
The last revision prior to the SCOPe 2.05 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 1.77 Å
R-factor: 0.179
AEROSPACI score: 0.55 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Acyl-CoA dehydrogenase family member 8, mitochondrial
    Species: Homo sapiens [TaxId:9606]
    Gene: ACAD8, ARC42
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d1rx0a1, d1rx0a2
  • Chain 'B':
    Compound: Acyl-CoA dehydrogenase family member 8, mitochondrial
    Species: Homo sapiens [TaxId:9606]
    Gene: ACAD8, ARC42
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d1rx0b1, d1rx0b2
  • Chain 'C':
    Compound: Acyl-CoA dehydrogenase family member 8, mitochondrial
    Species: Homo sapiens [TaxId:9606]
    Gene: ACAD8, ARC42
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d1rx0c1, d1rx0c2
  • Chain 'D':
    Compound: Acyl-CoA dehydrogenase family member 8, mitochondrial
    Species: Homo sapiens [TaxId:9606]
    Gene: ACAD8, ARC42
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d1rx0d1, d1rx0d2
  • Heterogens: EDO, FAD, 2MC, ACY, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1rx0A (A:)
mvqtghrsltscidpsmglneeqkefqkvafdfaaremapnmaewdqkelfpvdvmrkaa
qlgfggvyiqtdvggsglsrldtsvifealatgctsttayisihnmcawmidsfgneeqr
hkfcpplctmekfasycltepgsgsdaaslltsakkqgdhyilngskafisgagesdiyv
vmcrtggpgpkgiscivvekgtpglsfgkkekkvgwnsqptravifedcavpvanrigse
gqgfliavrglnggriniascslgaahasviltrdhlnvrkqfgeplasnqylqftladm
atrlvaarlmvrnaavalqeerkdavalcsmaklfatdecfaicnqalqmhggygylkdy
avqqyvrdsrvhqilegsnevmrilisrsllqe

    Sequence, based on observed residues (ATOM records): (download) 
    >1rx0A (A:)
tscidpsmglneeqkefqkvafdfaaremapnmaewdqkelfpvdvmrkaaqlgfggvyi
qtdvggsglsrldtsvifealatgctsttayisihnmcawmidsfgneeqrhkfcpplct
mekfasycltepgsgsdaaslltsakkqgdhyilngskafisgagesdiyvvmcrtggpg
pkgiscivvekgtpglsfgkkekkvgwnsqptravifedcavpvanrigsegqgfliavr
glnggriniascslgaahasviltrdhlnvrkqfgeplasnqylqftladmatrlvaarl
mvrnaavalqeerkdavalcsmaklfatdecfaicnqalqmhggygylkdyavqqyvrds
rvhqilegsnevmrilisrsllqe

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1rx0B (B:)
mvqtghrsltscidpsmglneeqkefqkvafdfaaremapnmaewdqkelfpvdvmrkaa
qlgfggvyiqtdvggsglsrldtsvifealatgctsttayisihnmcawmidsfgneeqr
hkfcpplctmekfasycltepgsgsdaaslltsakkqgdhyilngskafisgagesdiyv
vmcrtggpgpkgiscivvekgtpglsfgkkekkvgwnsqptravifedcavpvanrigse
gqgfliavrglnggriniascslgaahasviltrdhlnvrkqfgeplasnqylqftladm
atrlvaarlmvrnaavalqeerkdavalcsmaklfatdecfaicnqalqmhggygylkdy
avqqyvrdsrvhqilegsnevmrilisrsllqe

    Sequence, based on observed residues (ATOM records): (download) 
    >1rx0B (B:)
tscidpsmglneeqkefqkvafdfaaremapnmaewdqkelfpvdvmrkaaqlgfggvyi
qtdvggsglsrldtsvifealatgctsttayisihnmcawmidsfgneeqrhkfcpplct
mekfasycltepgsgsdaaslltsakkqgdhyilngskafisgagesdiyvvmcrtggpg
pkgiscivvekgtpglsfgkkekkvgwnsqptravifedcavpvanrigsegqgfliavr
glnggriniascslgaahasviltrdhlnvrkqfgeplasnqylqftladmatrlvaarl
mvrnaavalqeerkdavalcsmaklfatdecfaicnqalqmhggygylkdyavqqyvrds
rvhqilegsnevmrilisrsllqe

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1rx0C (C:)
mvqtghrsltscidpsmglneeqkefqkvafdfaaremapnmaewdqkelfpvdvmrkaa
qlgfggvyiqtdvggsglsrldtsvifealatgctsttayisihnmcawmidsfgneeqr
hkfcpplctmekfasycltepgsgsdaaslltsakkqgdhyilngskafisgagesdiyv
vmcrtggpgpkgiscivvekgtpglsfgkkekkvgwnsqptravifedcavpvanrigse
gqgfliavrglnggriniascslgaahasviltrdhlnvrkqfgeplasnqylqftladm
atrlvaarlmvrnaavalqeerkdavalcsmaklfatdecfaicnqalqmhggygylkdy
avqqyvrdsrvhqilegsnevmrilisrsllqe

    Sequence, based on observed residues (ATOM records): (download) 
    >1rx0C (C:)
scidpsmglneeqkefqkvafdfaaremapnmaewdqkelfpvdvmrkaaqlgfggvyiq
tdvggsglsrldtsvifealatgctsttayisihnmcawmidsfgneeqrhkfcpplctm
ekfasycltepgsgsdaaslltsakkqgdhyilngskafisgagesdiyvvmcrtggpgp
kgiscivvekgtpglsfgkkekkvgwnsqptravifedcavpvanrigsegqgfliavrg
lnggriniascslgaahasviltrdhlnvrkqfgeplasnqylqftladmatrlvaarlm
vrnaavalqeerkdavalcsmaklfatdecfaicnqalqmhggygylkdyavqqyvrdsr
vhqilegsnevmrilisrsllqe

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1rx0D (D:)
mvqtghrsltscidpsmglneeqkefqkvafdfaaremapnmaewdqkelfpvdvmrkaa
qlgfggvyiqtdvggsglsrldtsvifealatgctsttayisihnmcawmidsfgneeqr
hkfcpplctmekfasycltepgsgsdaaslltsakkqgdhyilngskafisgagesdiyv
vmcrtggpgpkgiscivvekgtpglsfgkkekkvgwnsqptravifedcavpvanrigse
gqgfliavrglnggriniascslgaahasviltrdhlnvrkqfgeplasnqylqftladm
atrlvaarlmvrnaavalqeerkdavalcsmaklfatdecfaicnqalqmhggygylkdy
avqqyvrdsrvhqilegsnevmrilisrsllqe

    Sequence, based on observed residues (ATOM records): (download) 
    >1rx0D (D:)
tscidpsmglneeqkefqkvafdfaaremapnmaewdqkelfpvdvmrkaaqlgfggvyi
qtdvggsglsrldtsvifealatgctsttayisihnmcawmidsfgneeqrhkfcpplct
mekfasycltepgsgsdaaslltsakkqgdhyilngskafisgagesdiyvvmcrtggpg
pkgiscivvekgtpglsfgkkekkvgwnsqptravifedcavpvanrigsegqgfliavr
glnggriniascslgaahasviltrdhlnvrkqfgeplasnqylqftladmatrlvaarl
mvrnaavalqeerkdavalcsmaklfatdecfaicnqalqmhggygylkdyavqqyvrds
rvhqilegsnevmrilisrsllqe