PDB entry 1rtf

View 1rtf on RCSB PDB site
Description: complex of benzamidine with the catalytic domain of human two chain tissue plasminogen activator [(tc)-t-pa]
Class: serine protease
Keywords: serine protease, fibrinolytic enzymes
Deposited on 1995-11-10, released 1997-01-11
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.184
AEROSPACI score: 0.37 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: two chain tissue plasminogen activator
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 1RTF
    Domains in SCOPe 2.08: d1rtf.1
  • Chain 'B':
    Compound: two chain tissue plasminogen activator
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1rtf.1
  • Heterogens: PO4, BEN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1rtfA (A:)
syqstcglrqysqrqrr

    Sequence, based on observed residues (ATOM records): (download) 
    >1rtfA (A:)
tcglrqys

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1rtfB (B:)
ikgglfadiashpwqaaifakhrrspgerflcggilisscwilsaahcfqerfpphhltv
ilgrtyrvvpgeeeqkfevekyivhkefdddtydndiallqlksdssrcaqessvvrtvc
lppadlqlpdwtecelsgygkhealspfyserlkeahvrlypssrctsqhllnrtvtdnm
lcagdtrsggpqanlhdacqgdsggplvclndgrmtlvgiiswglgcgqkdvpgvytkvt
nyldwirdnmrp

    Sequence, based on observed residues (ATOM records): (download) 
    >1rtfB (B:)
ikgglfadiashpwqaaifakhrgerflcggilisscwilsaahcfqerfpphhltvilg
rtyrvvpgeeeqkfevekyivhkefdddtydndiallqlksdssrcaqessvvrtvclpp
adlqlpdwtecelsgygkhealspfyserlkeahvrlypssrctsqhllnrtvtdnmlca
gdtrsnlhdacqgdsggplvclndgrmtlvgiiswglgcgqkdvpgvytkvtnyldwird
nmrp