PDB entry 1rrv

View 1rrv on RCSB PDB site
Description: X-ray crystal structure of TDP-vancosaminyltransferase GtfD as a complex with TDP and the natural substrate, desvancosaminyl vancomycin.
Class: transferase/antibiotic
Keywords: gt-b, glycosyltransferase, rossmann fold, glycopeptide, vacosamycin, antibiotic, transferase-antibiotic complex
Deposited on 2003-12-09, released 2004-05-18
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-11-01, with a file datestamp of 2017-10-27.
Experiment type: XRAY
Resolution: 2 Å
R-factor: N/A
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: glycosyltransferase gtfd
    Species: AMYCOLATOPSIS ORIENTALIS [TaxId:31958]
    Gene: gtfD
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9AFC7 (0-End)
      • cloning artifact (194-196)
    • PDB 1RRV
    Domains in SCOPe 2.07: d1rrva_
  • Chain 'B':
    Compound: glycosyltransferase gtfd
    Species: AMYCOLATOPSIS ORIENTALIS [TaxId:31958]
    Gene: gtfD
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9AFC7 (0-End)
      • cloning artifact (194-196)
    • PDB 1RRV
    Domains in SCOPe 2.07: d1rrvb_
  • Chain 'C':
    Compound: desvancosaminyl vancomycin
    Species: AMYCOLATOPSIS ORIENTALIS [TaxId:31958]
    Database cross-references and differences (RAF-indexed):
    • NOR NOR00681 (0-6)
  • Chain 'D':
    Compound: desvancosaminyl vancomycin
    Species: AMYCOLATOPSIS ORIENTALIS [TaxId:31958]
    Database cross-references and differences (RAF-indexed):
    • NOR NOR00681 (0-6)
  • Heterogens: K, TYD, GOL, BGC, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1rrvA (A:)
mrvllsvcgtrgdveigvaladrlkalgvqtrmcappaaeerlaevgvphvpvglpqhmm
lqegmpppppeeeqrlaamtvemqfdavpgaaegcaavvavgdlaaatgvrsvaeklglp
ffysvpspvylasphlppaydepttpgvtdirvlweeraarfadrygptlnrrraeiglp
pvedvfgyghgerpllaadpvlaplqpdvdavqtgawllsderplppeleaflaagsppv
higfgsssgrgiadaakvaveairaqgrrvilsrgwtelvlpddrddcfaidevnfqalf
rrvaavihhgsagtehvatragvpqlviprntdqpyfagrvaalgigvahdgptptfesl
saalttvlapetraraeavagmvltdgaaaaadlvlaavgrekpavpalehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >1rrvA (A:)
mrvllsvcgtrgdveigvaladrlkalgvqtrmcappaaeerlaevgvphvpvglpqhmm
lqegmpppppeeeqrlaamtvemqfdavpgaaegcaavvavgdlaaatgvrsvaeklglp
ffysvpspvylasphlppaydepttpgvtdirvlweeraarfadrygptlnrrraeiglp
pvedvfgyghgerpllaadpvlaplqpdvdavqtgawllsderplppeleaflaagsppv
higfgsssgrgiadaakvaveairaqgrrvilsrgwtelvlpddrddcfaidevnfqalf
rrvaavihhgsagtehvatragvpqlviprntdqpyfagrvaalgigvahdgptptfesl
saalttvlapetraraeavagmvltdgaaaaadlvlaavgr

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1rrvB (B:)
mrvllsvcgtrgdveigvaladrlkalgvqtrmcappaaeerlaevgvphvpvglpqhmm
lqegmpppppeeeqrlaamtvemqfdavpgaaegcaavvavgdlaaatgvrsvaeklglp
ffysvpspvylasphlppaydepttpgvtdirvlweeraarfadrygptlnrrraeiglp
pvedvfgyghgerpllaadpvlaplqpdvdavqtgawllsderplppeleaflaagsppv
higfgsssgrgiadaakvaveairaqgrrvilsrgwtelvlpddrddcfaidevnfqalf
rrvaavihhgsagtehvatragvpqlviprntdqpyfagrvaalgigvahdgptptfesl
saalttvlapetraraeavagmvltdgaaaaadlvlaavgrekpavpalehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >1rrvB (B:)
mrvllsvcgtrgdveigvaladrlkalgvqtrmcappaaeerlaevgvphvpvglpqhmm
lqegmpppppeeeqrlaamtvemqfdavpgaaegcaavvavgdlaaatgvrsvaeklglp
ffysvpspvylasphlppaydepttpgvtdirvlweeraarfadrygptlnrrraeiglp
pvedvfgyghgerpllaadpvlaplqpdvdavqtgawllsderplppeleaflaagsppv
higfgsssgrgiadaakvaveairaqgrrvilsrgwtelvlpddrddcfaidevnfqalf
rrvaavihhgsagtehvatragvpqlviprntdqpyfagrvaalgigvahdgptptfesl
saalttvlapetraraeavagmvltdgaaaaadlvlaavg

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    No sequence available.