PDB entry 1ror

View 1ror on RCSB PDB site
Description: crystal structures of the catalytic domain of phosphodiesterase 4b2b complexed with amp
Class: hydrolase
Keywords: pde, amp, hydrolase
Deposited on 2003-12-02, released 2004-12-07
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-11-16, with a file datestamp of 2011-11-11.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.209
AEROSPACI score: 0.44 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: cAMP-specific 3',5'-cyclic phosphodiesterase 4B
    Species: Homo sapiens [TaxId:9606]
    Gene: PDE4B
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q07343 (1-End)
      • engineered mutation (336)
      • engineered mutation (338)
    Domains in SCOPe 2.08: d1rora_
  • Chain 'B':
    Compound: cAMP-specific 3',5'-cyclic phosphodiesterase 4B
    Species: Homo sapiens [TaxId:9606]
    Gene: PDE4B
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q07343 (1-End)
      • engineered mutation (336)
    Domains in SCOPe 2.08: d1rorb_
  • Heterogens: ZN, AMP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1rorA (A:)
msisrfgvntenedhlakeledlnkwglnifnvagyshnrpltcimyaifqerdllktfr
issdtfitymmtledhyhsdvayhnslhaadvaqsthvllstpaldavftdleilaaifa
aaihdvdhpgvsnqflintnselalmyndesvlenhhlavgfkllqeehcdifmnltkkq
rqtlrkmvidmvlatdmskhmslladlktmvetkkvtssgvllldnytdriqvlrnmvhc
adlsnptkslelyrqwtdrimeeffqqgdkerergmeispmcdkhtasveksqvgfidyi
vhplwetwadlvqpdaqdildtlednrnwyqsmipqapappldeqnrdcqglmekfqfel
tldeedsegpekegeghs

    Sequence, based on observed residues (ATOM records): (download) 
    >1rorA (A:)
sisrfgvntenedhlakeledlnkwglnifnvagyshnrpltcimyaifqerdllktfri
ssdtfitymmtledhyhsdvayhnslhaadvaqsthvllstpaldavftdleilaaifaa
aihdvdhpgvsnqflintnselalmyndesvlenhhlavgfkllqeehcdifmnltkkqr
qtlrkmvidmvlatdmskhmslladlktmvetkkvtssgvllldnytdriqvlrnmvhca
dlsnptkslelyrqwtdrimeeffqqgdkerergmeispmcdkhtasveksqvgfidyiv
hplwetwadlvqpdaqdildtlednrnwyqsmipqapa

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1rorB (B:)
msisrfgvntenedhlakeledlnkwglnifnvagyshnrpltcimyaifqerdllktfr
issdtfitymmtledhyhsdvayhnslhaadvaqsthvllstpaldavftdleilaaifa
aaihdvdhpgvsnqflintnselalmyndesvlenhhlavgfkllqeehcdifmnltkkq
rqtlrkmvidmvlatdmskhmslladlktmvetkkvtssgvllldnytdriqvlrnmvhc
adlsnptkslelyrqwtdrimeeffqqgdkerergmeispmcdkhtasveksqvgfidyi
vhplwetwadlvqpdaqdildtlednrnwyqsmipqapappldeqnrdcqglmekfqfel
tldeedsegpekegeghs

    Sequence, based on observed residues (ATOM records): (download) 
    >1rorB (B:)
sisrfgvntenedhlakeledlnkwglnifnvagyshnrpltcimyaifqerdllktfri
ssdtfitymmtledhyhsdvayhnslhaadvaqsthvllstpaldavftdleilaaifaa
aihdvdhpgvsnqflintnselalmyndesvlenhhlavgfkllqeehcdifmnltkkqr
qtlrkmvidmvlatdmskhmslladlktmvetkkvtssgvllldnytdriqvlrnmvhca
dlsnptkslelyrqwtdrimeeffqqgdkerergmeispmcdkhtasveksqvgfidyiv
hplwetwadlvqpdaqdildtlednrnwyqsmipqap