PDB entry 1rlz

View 1rlz on RCSB PDB site
Description: Deoxyhypusine synthase holoenzyme in its high ionic strength, low pH crystal form
Class: transferase
Keywords: Rossmann Fold, NAD cofactor, deoxyhypusine, hypusine, spermidine, TRANSFERASE
Deposited on 2003-11-26, released 2004-07-13
The last revision prior to the SCOPe 2.08 freeze date was dated 2014-11-12, with a file datestamp of 2014-11-07.
Experiment type: XRAY
Resolution: 2.15 Å
R-factor: 0.199
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: deoxyhypusine synthase
    Species: Homo sapiens [TaxId:9606]
    Gene: DHPS, DS
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1rlza_
  • Heterogens: NAD, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >1rlzA (A:)
    megslereapagalaavlkhsstlppestqvrgydfnrgvnyralleafgttgfqatnfg
    ravqqvnamiekkleplsqdedqhadltqsrrpltsctiflgytsnlissgiretirylv
    qhnmvdvlvttaggveedlikclaptylgefslrgkelrenginrignllvpnenyckfe
    dwlmpildqmvmeqntegvkwtpskmiarlgkeinnpesvyywaqknhipvfspaltdgs
    lgdmiffhsyknpglvldivedlrlintqaifakctgmiilgggvvkhhiananlmrnga
    dyavyintaqefdgsdsgarpdeavswgkirvdaqpvkvyadaslvfpllvaetfaqkmd
    afmhekned
    

    Sequence, based on observed residues (ATOM records): (download)
    >1rlzA (A:)
    apagalaavlkhsstlppestqvrgydfnrgvnyralleafgttgfqatnfgravqqvna
    miekklepltsctiflgytsnlissgiretirylvqhnmvdvlvttaggveedlikclap
    tylgefslrgkelrenginrignllvpnenyckfedwlmpildqmvmeqntegvkwtpsk
    miarlgkeinnpesvyywaqknhipvfspaltdgslgdmiffhsyknpglvldivedlrl
    intqaifakctgmiilgggvvkhhiananlmrngadyavyintaqefdgsdsgarpdeav
    swgkirvdaqpvkvyadaslvfpllvaetfaqkmdafmhekned