PDB entry 1rew

View 1rew on RCSB PDB site
Description: Structural refinement of the complex of bone morphogenetic protein 2 and its type IA receptor
Class: hormone/growth factor/signaling protein
Keywords: TGF-beta fold; BRIA-fold; 3-finger toxin fold, HORMONE-GROWTH FACTOR-SIGNALING PROTEIN COMPLEX
Deposited on 2003-11-07, released 2004-05-04
The last revision prior to the SCOPe 2.06 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 1.86 Å
R-factor: 0.208
AEROSPACI score: 0.45 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Bone morphogenetic protein 2
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d1rewa_
  • Chain 'B':
    Compound: Bone morphogenetic protein 2
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d1rewb_
  • Chain 'C':
    Compound: Bone morphogenetic protein receptor type IA
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d1rewc_
  • Chain 'D':
    Compound: Bone morphogenetic protein receptor type IA
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d1rewd_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1rewA (A:)
qakhkqrkrlkssckrhplyvdfsdvgwndwivappgyhafychgecpfpladhlnstnh
aivqtlvnsvnskipkaccvptelsaismlyldenekvvlknyqdmvvegcgcr

    Sequence, based on observed residues (ATOM records): (download) 
    >1rewA (A:)
ssckrhplyvdfsdvgwndwivappgyhafychgecpfpladhlnstnhaivqtlvnsvn
skipkaccvptelsaismlyldenekvvlknyqdmvvegcgcr

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1rewB (B:)
qakhkqrkrlkssckrhplyvdfsdvgwndwivappgyhafychgecpfpladhlnstnh
aivqtlvnsvnskipkaccvptelsaismlyldenekvvlknyqdmvvegcgcr

    Sequence, based on observed residues (ATOM records): (download) 
    >1rewB (B:)
ssckrhplyvdfsdvgwndwivappgyhafychgecpfpladhlnstnhaivqtlvnsvn
skipkaccvptelsaismlyldenekvvlknyqdmvvegcgcr

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1rewC (C:)
gsgamaqnldsmlhgtgmksdsdqkksengvtlapedtlpflkcycsghcpddainntci
tnghcfaiieeddqgettlasgcmkyegsdfqckdspkaqlrrtieccrtnlcnqylqpt
lppvvigpffdgsir

    Sequence, based on observed residues (ATOM records): (download) 
    >1rewC (C:)
tlpflkcycsghcpddainntcitnghcfaiieeddqgettlasgcmkyegsdfqckdsp
kaqlrrtieccrtnlcnqylqptlpp

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1rewD (D:)
gsgamaqnldsmlhgtgmksdsdqkksengvtlapedtlpflkcycsghcpddainntci
tnghcfaiieeddqgettlasgcmkyegsdfqckdspkaqlrrtieccrtnlcnqylqpt
lppvvigpffdgsir

    Sequence, based on observed residues (ATOM records): (download) 
    >1rewD (D:)
tlpflkcycsghcpddainntcitnghcfaiieeddqgettlasgcmkyegsdfqckdsp
kaqlrrtieccrtnlcnqylqptlppvvi