PDB entry 1re4

View 1re4 on RCSB PDB site
Description: Crystal Structure of Fragment D of BbetaD398A Fibrinogen
Class: blood clotting
Keywords: RECOMBINANT FIBRINOGEN FRAGMENT D, RECOMBINANT FIBRINOGEN, Mutant fibrinogen, variant fibrinogen, BbetaD398A fibrinogen, BLOOD CLOTTING
Deposited on 2003-11-06, released 2004-05-25
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-07-04.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: N/A
AEROSPACI score: 0.23 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Fibrinogen alpha/alpha-E Chain
    Species: Homo sapiens [TaxId:9606]
    Gene: FGA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1re4a_
  • Chain 'B':
    Compound: fibrinogen beta chain
    Species: Homo sapiens [TaxId:9606]
    Gene: FGB
    Database cross-references and differences (RAF-indexed):
    • Uniprot P02675
      • engineered (249)
    Domains in SCOPe 2.08: d1re4b1, d1re4b2
  • Chain 'C':
    Compound: Fibrinogen gamma chain
    Species: Homo sapiens [TaxId:9606]
    Gene: FGG
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1re4c1, d1re4c2
  • Chain 'D':
    Compound: Fibrinogen alpha/alpha-E Chain
    Species: Homo sapiens [TaxId:9606]
    Gene: FGA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1re4d_
  • Chain 'E':
    Compound: fibrinogen beta chain
    Species: Homo sapiens [TaxId:9606]
    Gene: FGB
    Database cross-references and differences (RAF-indexed):
    • Uniprot P02675
      • engineered (249)
    Domains in SCOPe 2.08: d1re4e1, d1re4e2
  • Chain 'F':
    Compound: Fibrinogen gamma chain
    Species: Homo sapiens [TaxId:9606]
    Gene: FGG
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1re4f1, d1re4f2
  • Heterogens: NAG, CA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1re4A (A:)
viekvqhiqllqknvraqlvdmkrlevdidikirscrgscsralarevdlkdyedqqkql
eqviak

    Sequence, based on observed residues (ATOM records): (download) 
    >1re4A (A:)
viekvqhiqllqknvraqlvdmkrlevdidikirscrgscsralarevdlkdyedqqkql
eqvia

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1re4B (B:)
hqlyidetvnsniptnlrvlrsilenlrskiqklesdvsaqmeycrtpctvscnipvvsg
keceeiirkggetsemyliqpdssvkpyrvycdmntenggwtviqnrqdgsvdfgrkwdp
ykqgfgnvatntdgknycglpgeywlgndkisqltrmgptelliemedwkgdkvkahygg
ftvqneankyqisvnkyrgtagnalmdgasqlmgenrtmtihngmffstydrdndgwlts
dprkqcskeagggwwynrchaanpngryywggqytwdmakhgtddgvvwmnwkgswysmr
kmsmkirpffpqq

    Sequence, based on observed residues (ATOM records): (download) 
    >1re4B (B:)
detvnsniptnlrvlrsilenlrskiqklesdvsaqmeycrtpctvscnipvvsgkecee
iirkggetsemyliqpdssvkpyrvycdmntenggwtviqnrqdgsvdfgrkwdpykqgf
gnvatntdgknycglpgeywlgndkisqltrmgptelliemedwkgdkvkahyggftvqn
eankyqisvnkyrgtagnalmdgasqlmgenrtmtihngmffstydrdndgwltsdprkq
cskeagggwwynrchaanpngryywggqytwdmakhgtddgvvwmnwkgswysmrkmsmk
irpffp

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1re4C (C:)
yeasilthdssirylqeiynsnnqkivnlkekvaqleaqcqepckdtvqihditgkdcqd
iankgakqsglyfikplkanqqflvyceidgsgngwtvfqkrldgsvdfkknwiqykegf
ghlsptgttefwlgnekihlistqsaipyalrveledwngrtstadyamfkvgpeadkyr
ltyayfaggdagdafdgfdfgddpsdkfftshngmqfstwdndndkfegncaeqdgsgww
mnkchaghlngvyyqggtyskastpngydngiiwatwktrwysmkkttmkiipfnrltig
egqqhhlggak

    Sequence, based on observed residues (ATOM records): (download) 
    >1re4C (C:)
yeasilthdssirylqeiynsnnqkivnlkekvaqleaqcqepckdtvqihditgkdcqd
iankgakqsglyfikplkanqqflvyceidgsgngwtvfqkrldgsvdfkknwiqykegf
ghlsptgttefwlgnekihlistqsaipyalrveledwngrtstadyamfkvgpeadkyr
ltyayfaggdagdafdgfdfgddpsdkfftshngmqfstwdndndkfegncaeqdgsgww
mnkchaghlngvyyqggtyskastpngydngiiwatwktrwysmkkttmkiipfnrlt

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1re4D (D:)
viekvqhiqllqknvraqlvdmkrlevdidikirscrgscsralarevdlkdyedqqkql
eqviak

    Sequence, based on observed residues (ATOM records): (download) 
    >1re4D (D:)
kvqhiqllqknvraqlvdmkrlevdidikirscrgscsralarevdlkdyedqqkqleqv

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >1re4E (E:)
hqlyidetvnsniptnlrvlrsilenlrskiqklesdvsaqmeycrtpctvscnipvvsg
keceeiirkggetsemyliqpdssvkpyrvycdmntenggwtviqnrqdgsvdfgrkwdp
ykqgfgnvatntdgknycglpgeywlgndkisqltrmgptelliemedwkgdkvkahygg
ftvqneankyqisvnkyrgtagnalmdgasqlmgenrtmtihngmffstydrdndgwlts
dprkqcskeagggwwynrchaanpngryywggqytwdmakhgtddgvvwmnwkgswysmr
kmsmkirpffpqq

    Sequence, based on observed residues (ATOM records): (download) 
    >1re4E (E:)
rvlrsilenlrskiqklesdvsaqmeycrtpctvscnipvvsgkeceeiirkggetsemy
liqpdssvkpyrvycdmntenggwtviqnrqdgsvdfgrkwdpykqgfgnvatntdgkny
cglpgeywlgndkisqltrmgptelliemedwkgdkvkahyggftvqneankyqisvnky
rgtagnalmdgasqlmgenrtmtihngmffstydrdndgwltsdprkqcskeagggwwyn
rchaanpngryywggqytwdmakhgtddgvvwmnwkgswysmrkmsmkirpffp

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >1re4F (F:)
yeasilthdssirylqeiynsnnqkivnlkekvaqleaqcqepckdtvqihditgkdcqd
iankgakqsglyfikplkanqqflvyceidgsgngwtvfqkrldgsvdfkknwiqykegf
ghlsptgttefwlgnekihlistqsaipyalrveledwngrtstadyamfkvgpeadkyr
ltyayfaggdagdafdgfdfgddpsdkfftshngmqfstwdndndkfegncaeqdgsgww
mnkchaghlngvyyqggtyskastpngydngiiwatwktrwysmkkttmkiipfnrltig
egqqhhlggak

    Sequence, based on observed residues (ATOM records): (download) 
    >1re4F (F:)
hdssirylqeiynsnnqkivnlkekvaqleaqcqepckdtvqihditgkdcqdiankgak
qsglyfikplkanqqflvyceidgsgngwtvfqkrldgsvdfkknwiqykegfghlsptg
ttefwlgnekihlistqsaipyalrveledwngrtstadyamfkvgpeadkyrltyayfa
ggdagdafdgfdfgddpsdkfftshngmqfstwdndndkfegncaeqdgsgwwmnkchag
hlngvyyqggtyskastpngydngiiwatwktrwysmkkttmkiipfnrlt