PDB entry 1rd3

View 1rd3 on RCSB PDB site
Description: 2.5A Structure of Anticoagulant Thrombin Variant E217K
Class: hydrolase
Keywords: hydrolase
Deposited on 2003-11-05, released 2004-05-04
The last revision prior to the SCOP 1.75 freeze date was dated 2004-05-04, with a file datestamp of 2007-06-28.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.229
AEROSPACI score: 0.37 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Prothrombin
    Species: HOMO SAPIENS
    Gene: F2
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1rd3.1
  • Chain 'B':
    Compound: Prothrombin
    Species: HOMO SAPIENS
    Gene: F2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00734 (0-258)
      • engineered (144)
    Domains in SCOP 1.75: d1rd3.1
  • Chain 'C':
    Compound: Prothrombin
    Species: HOMO SAPIENS
    Gene: F2
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1rd3.2
  • Chain 'D':
    Compound: Prothrombin
    Species: HOMO SAPIENS
    Gene: F2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00734 (0-End)
      • engineered (144)
    Domains in SCOP 1.75: d1rd3.2
  • Heterogens: PO4, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1rd3A (A:)
tfgsgeadcglrplfekksledkterellesyidgr

    Sequence, based on observed residues (ATOM records): (download) 
    >1rd3A (A:)
tfgsgeadcglrplfekksledkterellesyi

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1rd3B (B:)
ivegsdaeigmspwqvmlfrkspqellcgaslisdrwvltaahcllyppwdknftendll
vrigkhsrtryerniekismlekiyihprynwrenldrdialmklkkpvafsdyihpvcl
pdretaasllqagykgrvtgwgnlketwtanvgkgqpsvlqvvnlpiverpvckdstrir
itdnmfcagykpdegkrgdacegdsggpfvmkspfnnrwyqmgivswgkgcdrdgkygfy
thvfrlkkwiqkvidqfge

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1rd3C (C:)
tfgsgeadcglrplfekksledkterellesyidgr

    Sequence, based on observed residues (ATOM records): (download) 
    >1rd3C (C:)
sgeadcglrplfekksledkterellesyid

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1rd3D (D:)
ivegsdaeigmspwqvmlfrkspqellcgaslisdrwvltaahcllyppwdknftendll
vrigkhsrtryerniekismlekiyihprynwrenldrdialmklkkpvafsdyihpvcl
pdretaasllqagykgrvtgwgnlketwtanvgkgqpsvlqvvnlpiverpvckdstrir
itdnmfcagykpdegkrgdacegdsggpfvmkspfnnrwyqmgivswgkgcdrdgkygfy
thvfrlkkwiqkvidqfge

    Sequence, based on observed residues (ATOM records): (download) 
    >1rd3D (D:)
ivegsdaeigmspwqvmlfrkspqellcgaslisdrwvltaahcllyppwdknftendll
vrigkhsrtryerniekismlekiyihprynwrenldrdialmklkkpvafsdyihpvcl
pdretaasllqagykgrvtgwgnlketwtanvgkgqpsvlqvvnlpiverpvckdstrir
itdnmfcagykpdegkrgdacegdsggpfvmkspfnnrwyqmgivswgkgcdrdgkygfy
thvfrlkkwiqkvidqfg