PDB entry 1r6z

View 1r6z on RCSB PDB site
Description: The Crystal Structure of the Argonaute2 PAZ domain (as a MBP fusion)
Class: gene regulation
Keywords: deviant OB fold, RNAi, GENE REGULATION
Deposited on 2003-10-17, released 2004-01-13
The last revision prior to the SCOPe 2.02 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: 0.227
AEROSPACI score: -1.76 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Chimera of Maltose-binding periplasmic protein and Argonaute 2
    Species: , [TaxId:562,7227]
    Gene: MALE, Argonaute 2 CG7439-PB
    Database cross-references and differences (RAF-indexed):
    • Uniprot P02928 (Start-366)
      • linker (367-372)
    • GB AAF49619 (373-End)
    Domains in SCOPe 2.02: d1r6za1, d1r6za2
  • Chain 'P':
    Compound: Chimera of Maltose-binding periplasmic protein and Argonaute 2
    Species: , [TaxId:562,7227]
    Gene: MALE, Argonaute 2 CG7439-PB
    Database cross-references and differences (RAF-indexed):
    • Uniprot P02928 (Start-366)
      • linker (367-372)
    • GB AAF49619 (373-End)
    Domains in SCOPe 2.02: d1r6zp1, d1r6zp2
  • Chain 'Z':
    Compound: Chimera of Maltose-binding periplasmic protein and Argonaute 2
    Species: , [TaxId:562,7227]
    Gene: MALE, Argonaute 2 CG7439-PB
    Database cross-references and differences (RAF-indexed):
    • Uniprot P02928 (Start-366)
      • linker (367-372)
    • GB AAF49619 (373-End)
    Domains in SCOPe 2.02: d1r6zz1, d1r6zz2
  • Heterogens: MAL, NI, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1r6zA (A:)
mkieegklviwingdkgynglaevgkkfekdtgikvtvehpdkleekfpqvaatgdgpdi
ifwahdrfggyaqsgllaeitpdkafqdklypftwdavryngkliaypiavealsliynk
dllpnppktweeipaldkelkakgksalmfnlqepyftwpliaadggyafkyengkydik
dvgvdnagakagltflvdliknkhmnadtdysiaeaafnkgetamtingpwawsnidtsk
vnygvtvlptfkgqpskpfvgvlsaginaaspnkelakeflenylltdegleavnkdkpl
gavalksyeeelakdpriaatmenaqkgeimpnipqmsafwyavrtavinaasgrqtvde
alkdaqtnaaaefvdishksfpismpmieylerfslkakinnttnldysrrflepflrgi
nvvytppqsfqsaprvyrvnglsrapassetfehdgkkvtiasyfhsrnyplkfpqlhcl
nvgssiksillpielcsieegqalnrkdg

    Sequence, based on observed residues (ATOM records): (download) 
    >1r6zA (A:)
ieegklviwingdkgynglaevgkkfekdtgikvtvehpdkleekfpqvaatgdgpdiif
wahdrfggyaqsgllaeitpdkafqdklypftwdavryngkliaypiavealsliynkdl
lpnppktweeipaldkelkakgksalmfnlqepyftwpliaadggyafkyengkydikdv
gvdnagakagltflvdliknkhmnadtdysiaeaafnkgetamtingpwawsnidtskvn
ygvtvlptfkgqpskpfvgvlsaginaaspnkelakeflenylltdegleavnkdkplga
valksyeeelakdpriaatmenaqkgeimpnipqmsafwyavrtavinaasgrqtvdeal
kdaqtnaaaefvdishksfpismpmieylerfslkakinnttnldysrrflepflrginv
vytppqsfqsaprvyrvnglsrapassetfehdgkkvtiasyfhsrnyplkfpqlhclnv
gssiksillpielcsie

  • Chain 'P':
    Sequence, based on SEQRES records: (download) 
    >1r6zP (P:)
mkieegklviwingdkgynglaevgkkfekdtgikvtvehpdkleekfpqvaatgdgpdi
ifwahdrfggyaqsgllaeitpdkafqdklypftwdavryngkliaypiavealsliynk
dllpnppktweeipaldkelkakgksalmfnlqepyftwpliaadggyafkyengkydik
dvgvdnagakagltflvdliknkhmnadtdysiaeaafnkgetamtingpwawsnidtsk
vnygvtvlptfkgqpskpfvgvlsaginaaspnkelakeflenylltdegleavnkdkpl
gavalksyeeelakdpriaatmenaqkgeimpnipqmsafwyavrtavinaasgrqtvde
alkdaqtnaaaefvdishksfpismpmieylerfslkakinnttnldysrrflepflrgi
nvvytppqsfqsaprvyrvnglsrapassetfehdgkkvtiasyfhsrnyplkfpqlhcl
nvgssiksillpielcsieegqalnrkdg

    Sequence, based on observed residues (ATOM records): (download) 
    >1r6zP (P:)
ieegklviwingdkgynglaevgkkfekdtgikvtvehpdkleekfpqvaatgdgpdiif
wahdrfggyaqsgllaeitpdkafqdklypftwdavryngkliaypiavealsliynkdl
lpnppktweeipaldkelkakgksalmfnlqepyftwpliaadggyafkyengkydikdv
gvdnagakagltflvdliknkhmnadtdysiaeaafnkgetamtingpwawsnidtskvn
ygvtvlptfkgqpskpfvgvlsaginaaspnkelakeflenylltdegleavnkdkplga
valksyeeelakdpriaatmenaqkgeimpnipqmsafwyavrtavinaasgrqtvdeal
kdaqtnaaaefvdishksfpismpmieylerfslkakinnttnldysrrflepflrginv
vytppqsfqsaprvyrvnglsrapassetfehdgkkvtiasyfhsrnyplkfpqlhclnv
gssiksillpielcsiee

  • Chain 'Z':
    Sequence, based on SEQRES records: (download) 
    >1r6zZ (Z:)
mkieegklviwingdkgynglaevgkkfekdtgikvtvehpdkleekfpqvaatgdgpdi
ifwahdrfggyaqsgllaeitpdkafqdklypftwdavryngkliaypiavealsliynk
dllpnppktweeipaldkelkakgksalmfnlqepyftwpliaadggyafkyengkydik
dvgvdnagakagltflvdliknkhmnadtdysiaeaafnkgetamtingpwawsnidtsk
vnygvtvlptfkgqpskpfvgvlsaginaaspnkelakeflenylltdegleavnkdkpl
gavalksyeeelakdpriaatmenaqkgeimpnipqmsafwyavrtavinaasgrqtvde
alkdaqtnaaaefvdishksfpismpmieylerfslkakinnttnldysrrflepflrgi
nvvytppqsfqsaprvyrvnglsrapassetfehdgkkvtiasyfhsrnyplkfpqlhcl
nvgssiksillpielcsieegqalnrkdg

    Sequence, based on observed residues (ATOM records): (download) 
    >1r6zZ (Z:)
eegklviwingdkgynglaevgkkfekdtgikvtvehpdkleekfpqvaatgdgpdiifw
ahdrfggyaqsgllaeitpdkafqdklypftwdavryngkliaypiavealsliynkdll
pnppktweeipaldkelkakgksalmfnlqepyftwpliaadggyafkyengkydikdvg
vdnagakagltflvdliknkhmnadtdysiaeaafnkgetamtingpwawsnidtskvny
gvtvlptfkgqpskpfvgvlsaginaaspnkelakeflenylltdegleavnkdkplgav
alksyeeelakdpriaatmenaqkgeimpnipqmsafwyavrtavinaasgrqtvdealk
daqtnaaaefvdishksfpismpmieylerfslkakinnttnldysrrflepflrginvv
ytppqsfqsaprvyrvnglsrapassetfehdgkkvtiasyfhsrnyplkfpqlhclnvg
ssiksillpielcsieegq