PDB entry 1r4f

View 1r4f on RCSB PDB site
Description: Inosine-Adenosine-Guanosine Preferring Nucleoside Hydrolase From Trypanosoma vivax: Trp260Ala Mutant In Complex With 3-Deaza-Adenosine
Class: hydrolase
Keywords: Rossmann fold, aromatic stacking, HYDROLASE
Deposited on 2003-10-06, released 2004-04-13
The last revision prior to the SCOPe 2.05 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.205
AEROSPACI score: 0.35 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: IAG-nucleoside hydrolase
    Species: Trypanosoma vivax [TaxId:5699]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9GPQ4 (13-338)
      • expression tag (12)
      • engineered (270)
      • see remark 999 (225)
    Domains in SCOPe 2.05: d1r4fa_
  • Chain 'B':
    Compound: IAG-nucleoside hydrolase
    Species: Trypanosoma vivax [TaxId:5699]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9GPQ4 (13-338)
      • expression tag (12)
      • engineered (270)
      • see remark 999 (225)
    Domains in SCOPe 2.05: d1r4fb_
  • Heterogens: CA, AD3, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1r4fA (A:)
mrgsphhhhhhgsaknvvldhdgnlddfvamvllasntekvrligalctdadcfvengfn
vtgkimclmhnnmnlplfpigksaatavnpfpkewrclaknmddmpilnipenvelwdki
kaenekyegqqlladlvmnseekvticvtgplsnvawcidkygekftskveecvimggav
dvrgnvflpstdgtaewniywdpasaktvfgcpglrrimfsldstntvpvrspyvqrfge
qtnfllsilvgtmwamcthcellrdgdgyyaadaltaayvvdqkvanvdpvpidvvvdkq
pnegatvrtdaenypltfvarnpeaeffldmllrsarac

    Sequence, based on observed residues (ATOM records): (download) 
    >1r4fA (A:)
saknvvldhdgnlddfvamvllasntekvrligalctdadcfvengfnvtgkimclmhnn
mnlplfpigksaatavnpfpkewrclaknmddmpilnipenvelwdkikaenekyegqql
ladlvmnseekvticvtgplsnvawcidkygekftskveecvimggavdvrgnvflpstd
gtaewniywdpasaktvfgcpglrrimfsldstntvpvrspyvqrfgeqtnfllsilvgt
mwamyaadaltaayvvdqkvanvdpvpidvvvdkqpnegatvrtdaenypltfvarnpea
effldmllrsarac

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1r4fB (B:)
mrgsphhhhhhgsaknvvldhdgnlddfvamvllasntekvrligalctdadcfvengfn
vtgkimclmhnnmnlplfpigksaatavnpfpkewrclaknmddmpilnipenvelwdki
kaenekyegqqlladlvmnseekvticvtgplsnvawcidkygekftskveecvimggav
dvrgnvflpstdgtaewniywdpasaktvfgcpglrrimfsldstntvpvrspyvqrfge
qtnfllsilvgtmwamcthcellrdgdgyyaadaltaayvvdqkvanvdpvpidvvvdkq
pnegatvrtdaenypltfvarnpeaeffldmllrsarac

    Sequence, based on observed residues (ATOM records): (download) 
    >1r4fB (B:)
saknvvldhdgnlddfvamvllasntekvrligalctdadcfvengfnvtgkimclmhnn
mnlplfpigksaatavnpfpkewrclaknmddmpilnipenvelwdkikaenekyegqql
ladlvmnseekvticvtgplsnvawcidkygekftskveecvimggavdvrgnvflpstd
gtaewniywdpasaktvfgcpglrrimfsldstntvpvrspyvqrfgeqtnfllsilvgt
mwamyaadaltaayvvdqkvanvdpvpidvvvdkqpnegatvrtdaenypltfvarnpea
effldmllrsarac