PDB entry 1r4c
View 1r4c on RCSB PDB site
Description: N-Truncated Human Cystatin C; Dimeric Form With 3D Domain Swapping
Class: hydrolase inhibitor
Keywords: human cystatin c, n-truncation, 3d domain swapping, amyloid formation, inhibitor of c1 and c13 cysteine proteases, amyloid angiopathy and cerebral hemorrhage, hydrolase inhibitor
Deposited on
2003-10-06, released
2004-09-21
The last revision prior to the SCOPe 2.03 freeze date was dated
2011-07-13, with a file datestamp of
2011-05-08.
Experiment type: XRAY
Resolution: 2.18 Å
R-factor: 0.22
AEROSPACI score: 0.36
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Cystatin C
Species: Homo sapiens [TaxId:9606]
Gene: CST3
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.03: d1r4ca_ - Chain 'B':
Compound: Cystatin C
Species: Homo sapiens [TaxId:9606]
Gene: CST3
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.03: d1r4cb_ - Chain 'C':
Compound: Cystatin C
Species: Homo sapiens [TaxId:9606]
Gene: CST3
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.03: d1r4cc_ - Chain 'D':
Compound: Cystatin C
Species: Homo sapiens [TaxId:9606]
Gene: CST3
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.03: d1r4cd_ - Chain 'E':
Compound: Cystatin C
Species: Homo sapiens [TaxId:9606]
Gene: CST3
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.03: d1r4ce_ - Chain 'F':
Compound: Cystatin C
Species: Homo sapiens [TaxId:9606]
Gene: CST3
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.03: d1r4cf_ - Chain 'G':
Compound: Cystatin C
Species: Homo sapiens [TaxId:9606]
Gene: CST3
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.03: d1r4cg_ - Chain 'H':
Compound: Cystatin C
Species: Homo sapiens [TaxId:9606]
Gene: CST3
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.03: d1r4ch_ - Heterogens: HOH
PDB Chain Sequences:
- Chain 'A':
Sequence; same for both SEQRES and ATOM records: (download)
>1r4cA (A:)
ggpmdasveeegvrraldfavgeynkasndmyhsralqvvrarkqivagvnyfldvelgr
ttctktqpnldncpfhdqphlkrkafcsfqiyavpwqgtmtlskstcqda
- Chain 'B':
Sequence; same for both SEQRES and ATOM records: (download)
>1r4cB (B:)
ggpmdasveeegvrraldfavgeynkasndmyhsralqvvrarkqivagvnyfldvelgr
ttctktqpnldncpfhdqphlkrkafcsfqiyavpwqgtmtlskstcqda
- Chain 'C':
Sequence; same for both SEQRES and ATOM records: (download)
>1r4cC (C:)
ggpmdasveeegvrraldfavgeynkasndmyhsralqvvrarkqivagvnyfldvelgr
ttctktqpnldncpfhdqphlkrkafcsfqiyavpwqgtmtlskstcqda
- Chain 'D':
Sequence; same for both SEQRES and ATOM records: (download)
>1r4cD (D:)
ggpmdasveeegvrraldfavgeynkasndmyhsralqvvrarkqivagvnyfldvelgr
ttctktqpnldncpfhdqphlkrkafcsfqiyavpwqgtmtlskstcqda
- Chain 'E':
Sequence; same for both SEQRES and ATOM records: (download)
>1r4cE (E:)
ggpmdasveeegvrraldfavgeynkasndmyhsralqvvrarkqivagvnyfldvelgr
ttctktqpnldncpfhdqphlkrkafcsfqiyavpwqgtmtlskstcqda
- Chain 'F':
Sequence; same for both SEQRES and ATOM records: (download)
>1r4cF (F:)
ggpmdasveeegvrraldfavgeynkasndmyhsralqvvrarkqivagvnyfldvelgr
ttctktqpnldncpfhdqphlkrkafcsfqiyavpwqgtmtlskstcqda
- Chain 'G':
Sequence; same for both SEQRES and ATOM records: (download)
>1r4cG (G:)
ggpmdasveeegvrraldfavgeynkasndmyhsralqvvrarkqivagvnyfldvelgr
ttctktqpnldncpfhdqphlkrkafcsfqiyavpwqgtmtlskstcqda
- Chain 'H':
Sequence; same for both SEQRES and ATOM records: (download)
>1r4cH (H:)
ggpmdasveeegvrraldfavgeynkasndmyhsralqvvrarkqivagvnyfldvelgr
ttctktqpnldncpfhdqphlkrkafcsfqiyavpwqgtmtlskstcqda