PDB entry 1r42

View 1r42 on RCSB PDB site
Description: Native Human Angiotensin Converting Enzyme-Related Carboxypeptidase (ACE2)
Class: hydrolase
Keywords: zinc metallopeptidase domain, collectrin homology domain, native or open conformation, chloride ion binding site, zinc binding site, HYDROLASE
Deposited on 2003-10-07, released 2004-02-03
The last revision prior to the SCOPe 2.01 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-25.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.235
AEROSPACI score: -1.66 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: angiotensin I converting enzyme 2
    Species: Homo sapiens [TaxId:9606]
    Gene: ACE2
    Database cross-references and differences (RAF-indexed):
    • GB NP_068576 (Start-614)
    Domains in SCOPe 2.01: d1r42a_
  • Chain 'B':
    Compound: disordered segment of collectrin homology domain
    Species: Homo sapiens [TaxId:9606]
    Gene: ACE2
    Database cross-references and differences (RAF-indexed):
    • PDB 1R42 (0-5)
  • Chain 'C':
    Compound: disordered segment of collectrin homology domain
    Species: Homo sapiens [TaxId:9606]
    Gene: ACE2
    Database cross-references and differences (RAF-indexed):
    • PDB 1R42 (0-19)
  • Chain 'D':
    Compound: disordered segment of collectrin homology domain
    Species: Homo sapiens [TaxId:9606]
    Gene: ACE2
    Database cross-references and differences (RAF-indexed):
    • PDB 1R42 (0-17)
  • Chain 'E':
    Compound: disordered segment of collectrin homology domain
    Species: Homo sapiens [TaxId:9606]
    Gene: ACE2
    Database cross-references and differences (RAF-indexed):
    • PDB 1R42 (0-13)
  • Heterogens: NAG, CL, ZN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >1r42A (A:)
    msssswlllslvavtaaqstieeqaktfldkfnheaedlfyqsslaswnyntniteenvq
    nmnnagdkwsaflkeqstlaqmyplqeiqnltvklqlqalqqngssvlsedkskrlntil
    ntmstiystgkvcnpdnpqeclllepglneimansldynerlwaweswrsevgkqlrply
    eeyvvlknemaranhyedygdywrgdyevngvdgydysrgqliedvehtfeeikplyehl
    hayvraklmnaypsyispigclpahllgdmwgrfwtnlysltvpfgqkpnidvtdamvdq
    awdaqrifkeaekffvsvglpnmtqgfwensmltdpgnvqkavchptawdlgkgdfrilm
    ctkvtmddfltahhemghiqydmayaaqpfllrnganegfheavgeimslsaatpkhlks
    igllspdfqedneteinfllkqaltivgtlpftymlekwrwmvfkgeipkdqwmkkwwem
    kreivgvvepvphdetycdpaslfhvsndysfiryytrtlyqfqfqealcqaakhegplh
    kcdisnsteagqklfnmlrlgksepwtlalenvvgaknmnvrpllnyfeplftwlkdqnk
    nsfvgwstdwspyad
    

    Sequence, based on observed residues (ATOM records): (download)
    >1r42A (A:)
    stieeqaktfldkfnheaedlfyqsslaswnyntniteenvqnmnnagdkwsaflkeqst
    laqmyplqeiqnltvklqlqalqqngssvlsedkskrlntilntmstiystgkvcnpdnp
    qeclllepglneimansldynerlwaweswrsevgkqlrplyeeyvvlknemaranhyed
    ygdywrgdyevngvdgydysrgqliedvehtfeeikplyehlhayvraklmnaypsyisp
    igclpahllgdmwgrfwtnlysltvpfgqkpnidvtdamvdqawdaqrifkeaekffvsv
    glpnmtqgfwensmltdpgnvqkavchptawdlgkgdfrilmctkvtmddfltahhemgh
    iqydmayaaqpfllrnganegfheavgeimslsaatpkhlksigllspdfqedneteinf
    llkqaltivgtlpftymlekwrwmvfkgeipkdqwmkkwwemkreivgvvepvphdetyc
    dpaslfhvsndysfiryytrtlyqfqfqealcqaakhegplhkcdisnsteagqklfnml
    rlgksepwtlalenvvgaknmnvrpllnyfeplftwlkdqnknsfvgwstdwspyad
    

  • Chain 'B':
    No sequence available.

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    No sequence available.

  • Chain 'E':
    No sequence available.