PDB entry 1r42

View 1r42 on RCSB PDB site
Description: Native Human Angiotensin Converting Enzyme-Related Carboxypeptidase (ACE2)
Class: hydrolase
Keywords: zinc metallopeptidase domain, collectrin homology domain, native or open conformation, chloride ion binding site, zinc binding site
Deposited on 2003-10-07, released 2004-02-03
The last revision prior to the SCOP 1.73 freeze date was dated 2004-04-27, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.235
AEROSPACI score: -1.67 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: angiotensin I converting enzyme 2
    Species: HOMO SAPIENS
    Gene: ACE2
    Database cross-references and differences (RAF-indexed):
    • GB NP_068576 (Start-614)
    Domains in SCOP 1.73: d1r42a_
  • Chain 'B':
    Compound: disordered segment of collectrin homology domain
    Species: HOMO SAPIENS
    Gene: ACE2
  • Chain 'C':
    Compound: disordered segment of collectrin homology domain
    Species: HOMO SAPIENS
    Gene: ACE2
  • Chain 'D':
    Compound: disordered segment of collectrin homology domain
    Species: HOMO SAPIENS
    Gene: ACE2
  • Chain 'E':
    Compound: disordered segment of collectrin homology domain
    Species: HOMO SAPIENS
    Gene: ACE2
  • Heterogens: NAG, CL, ZN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1r42A (A:)
msssswlllslvavtaaqstieeqaktfldkfnheaedlfyqsslaswnyntniteenvq
nmnnagdkwsaflkeqstlaqmyplqeiqnltvklqlqalqqngssvlsedkskrlntil
ntmstiystgkvcnpdnpqeclllepglneimansldynerlwaweswrsevgkqlrply
eeyvvlknemaranhyedygdywrgdyevngvdgydysrgqliedvehtfeeikplyehl
hayvraklmnaypsyispigclpahllgdmwgrfwtnlysltvpfgqkpnidvtdamvdq
awdaqrifkeaekffvsvglpnmtqgfwensmltdpgnvqkavchptawdlgkgdfrilm
ctkvtmddfltahhemghiqydmayaaqpfllrnganegfheavgeimslsaatpkhlks
igllspdfqedneteinfllkqaltivgtlpftymlekwrwmvfkgeipkdqwmkkwwem
kreivgvvepvphdetycdpaslfhvsndysfiryytrtlyqfqfqealcqaakhegplh
kcdisnsteagqklfnmlrlgksepwtlalenvvgaknmnvrpllnyfeplftwlkdqnk
nsfvgwstdwspyad

    Sequence, based on observed residues (ATOM records): (download) 
    >1r42A (A:)
stieeqaktfldkfnheaedlfyqsslaswnyntniteenvqnmnnagdkwsaflkeqst
laqmyplqeiqnltvklqlqalqqngssvlsedkskrlntilntmstiystgkvcnpdnp
qeclllepglneimansldynerlwaweswrsevgkqlrplyeeyvvlknemaranhyed
ygdywrgdyevngvdgydysrgqliedvehtfeeikplyehlhayvraklmnaypsyisp
igclpahllgdmwgrfwtnlysltvpfgqkpnidvtdamvdqawdaqrifkeaekffvsv
glpnmtqgfwensmltdpgnvqkavchptawdlgkgdfrilmctkvtmddfltahhemgh
iqydmayaaqpfllrnganegfheavgeimslsaatpkhlksigllspdfqedneteinf
llkqaltivgtlpftymlekwrwmvfkgeipkdqwmkkwwemkreivgvvepvphdetyc
dpaslfhvsndysfiryytrtlyqfqfqealcqaakhegplhkcdisnsteagqklfnml
rlgksepwtlalenvvgaknmnvrpllnyfeplftwlkdqnknsfvgwstdwspyad

  • Chain 'B':
    No sequence available.

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    No sequence available.

  • Chain 'E':
    No sequence available.