PDB entry 1r2h

View 1r2h on RCSB PDB site
Description: Human Bcl-XL containing an Ala to Leu mutation at position 142
Class: apoptosis
Keywords: Apoptosis, monomeric, alpha-helical, mutation
Deposited on 2003-09-26, released 2004-02-03
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-10-11, with a file datestamp of 2017-10-06.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: N/A
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: apoptosis regulator bcl-x
    Species: Homo sapiens [TaxId:9606]
    Gene: BCL-XL
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q07817 (0-End)
      • engineered (141)
    Domains in SCOPe 2.08: d1r2ha_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1r2hA (A:)
msqsnrelvvdflsyklsqkgyswsqfsdveenrteapegtesemetpsaingnpswhla
dspavngatghsssldarevipmaavkqalreagdefelryrrafsdltsqlhitpgtay
qsfeqvvnelfrdgvnwgrivlffsfggalcvesvdkemqvlvsriaawmatylndhlep
wiqenggwdtfvelygnnaaaesrkgqerfnehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >1r2hA (A:)
msqsnrelvvdflsyklsqkgyswsqfpmaavkqalreagdefelryrrafsdltsqlhi
tpgtayqsfeqvvnelfrdgvnwgrivlffsfggalcvesvdkemqvlvsriaawmatyl
ndhlepwiqenggwdtfvelyg