PDB entry 1r2g

View 1r2g on RCSB PDB site
Description: Human Bcl-XL containing a Phe to Trp mutation at position 97
Class: apoptosis
Keywords: Apoptosis, monomeric, alpha-helical, mutation
Deposited on 2003-09-26, released 2004-02-03
The last revision prior to the SCOP 1.75 freeze date was dated 2004-08-31, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: 0.191
AEROSPACI score: 0.36 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: apoptosis regulator bcl-x
    Species: HOMO SAPIENS
    Gene: BCL-XL
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q07817 (0-End)
      • engineered (96)
    Domains in SCOP 1.75: d1r2ga_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1r2gA (A:)
msqsnrelvvdflsyklsqkgyswsqfsdveenrteapegtesemetpsaingnpswhla
dspavngatghsssldarevipmaavkqalreagdewelryrrafsdltsqlhitpgtay
qsfeqvvnelfrdgvnwgrivaffsfggalcvesvdkemqvlvsriaawmatylndhlep
wiqenggwdtfvelygnnaaaesrkgqerfnehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >1r2gA (A:)
msqsnrelvvdflsyklsqkgyswsqfipmaavkqalreagdewelryrrafsdltsqlh
itpgtayqsfeqvvnelfrdgvnwgrivaffsfggalcvesvdkemqvlvsriaawmaty
lndhlepwiqenggwdtfvelyg