PDB entry 1r2b
View 1r2b on RCSB PDB site
Description: Crystal structure of the BCL6 BTB domain complexed with a SMRT co-repressor peptide
Class: transcription
Keywords: BTB domain, HDAC complex, B-cell lymphoma, transcriptional repression
Deposited on
2003-09-26, released
2003-12-23
The last revision prior to the SCOPe 2.08 freeze date was dated
2009-02-24, with a file datestamp of
2009-02-03.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.227
AEROSPACI score: 0.37
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: B-cell lymphoma 6 protein
Species: Homo sapiens [TaxId:9606]
Gene: BCL6
Database cross-references and differences (RAF-indexed):
- Uniprot P41182 (2-126)
- engineered (5)
- engineered (64)
- engineered (81)
Domains in SCOPe 2.08: d1r2ba_ - Chain 'B':
Compound: B-cell lymphoma 6 protein
Species: Homo sapiens [TaxId:9606]
Gene: BCL6
Database cross-references and differences (RAF-indexed):
- Uniprot P41182
- engineered (5)
- engineered (64)
- engineered (81)
Domains in SCOPe 2.08: d1r2bb_ - Chain 'C':
Compound: nuclear receptor co-repressor 2
Species: Homo sapiens [TaxId:9606]
Gene: NCOR2 OR CTG26
Database cross-references and differences (RAF-indexed):
- Chain 'D':
Compound: nuclear receptor co-repressor 2
Species: Homo sapiens [TaxId:9606]
Gene: NCOR2 OR CTG26
Database cross-references and differences (RAF-indexed):
- Heterogens: HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>1r2bA (A:)
gsadsqiqftrhasdvllnlnrlrsrdiltdvvivvsreqfrahktvlmacsglfysift
dqlkrnlsvinldpeinpegfnilldfmytsrlnlregnimavmatamylqmehvvdtcr
kfikase
Sequence, based on observed residues (ATOM records): (download)
>1r2bA (A:)
adsqiqftrhasdvllnlnrlrsrdiltdvvivvsreqfrahktvlmacsglfysiftdq
lkrnlsvinldpeinpegfnilldfmytsrlnlregnimavmatamylqmehvvdtcrkf
ikase
- Chain 'B':
Sequence, based on SEQRES records: (download)
>1r2bB (B:)
gsadsqiqftrhasdvllnlnrlrsrdiltdvvivvsreqfrahktvlmacsglfysift
dqlkrnlsvinldpeinpegfnilldfmytsrlnlregnimavmatamylqmehvvdtcr
kfikase
Sequence, based on observed residues (ATOM records): (download)
>1r2bB (B:)
dsqiqftrhasdvllnlnrlrsrdiltdvvivvsreqfrahktvlmacsglfysiftdql
krnlsvinldpeinpegfnilldfmytsrlnlregnimavmatamylqmehvvdtcrkfi
kas
- Chain 'C':
No sequence available.
- Chain 'D':
No sequence available.