PDB entry 1r1l

View 1r1l on RCSB PDB site
Description: Structure of dimeric antithrombin complexed with a P14-P9 reactive loop peptide and an exogenous tripeptide (formyl-norleucine-LF)
Class: hydrolase/hydrolase inhibitor
Keywords: serpin, loop-sheet polymer, beta-barrel, HYDROLASE-HYDROLASE INHIBITOR complex
Deposited on 2003-09-24, released 2004-10-05
The last revision prior to the SCOPe 2.07 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: 0.204
AEROSPACI score: 0.28 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'C':
    Compound: antithrombin P14-P9 peptide
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
    • PDB 1R1L (Start-5)
  • Chain 'D':
    Compound: EXOGENOUS TRIPEPTIDE formyl-(NLE)LF
    Database cross-references and differences (RAF-indexed):
    • PDB 1R1L (0-2)
  • Chain 'I':
    Compound: antithrombin-III
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1r1li_
  • Chain 'L':
    Compound: antithrombin-III
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1r1ll_
  • Heterogens: NAG, FOR, GOL, HOH

PDB Chain Sequences:

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    No sequence available.

  • Chain 'I':
    Sequence, based on SEQRES records: (download)
    >1r1lI (I:)
    hgspvdictakprdipmnpmciyrspekkatedegseqkipeatnrrvwelskansrfat
    tfyqhladskndndniflsplsistafamtklgacndtlqqlmevfkfdtisektsdqih
    fffaklncrlyrkankssklvsanrlfgdksltfnetyqdiselvygaklqpldfkenae
    qsraainkwvsnktegritdvipseaineltvlvlvntiyfkglwkskfspentrkelfy
    kadgescsasmmyqegkfryrrvaegtqvlelpfkgdditmvlilpkpekslakvekelt
    pevlqewldeleemmlvvhmprfriedgfslkeqlqdmglvdlfspeksklpgivaegrd
    dlyvsdafhkaflevneegseaaastavviagrslnpnrvtfkanrpflvfirevplnti
    ifmgrvanpcvk
    

    Sequence, based on observed residues (ATOM records): (download)
    >1r1lI (I:)
    vdictakprdipmnpmciyrspekkpeatnrrvwelskansrfattfyqhladskndndn
    iflsplsistafamtklgacndtlqqlmevfkfdtisektsdqihfffaklncrlyrkan
    kssklvsanrlfgdksltfnetyqdiselvygaklqpldfkenaeqsraainkwvsnkte
    gritdvipseaineltvlvlvntiyfkglwkskfspentrkelfykadgescsasmmyqe
    gkfryrrvaegtqvlelpfkgdditmvlilpkpekslakvekeltpevlqewldeleemm
    lvvhmprfriedgfslkeqlqdmglvdlfspeksklpgivaegrddlyvsdafhkaflev
    neegseaaastavviagrslnpnrvtfkanrpflvfirevplntiifmgrvanpcv
    

  • Chain 'L':
    Sequence, based on SEQRES records: (download)
    >1r1lL (L:)
    hgspvdictakprdipmnpmciyrspekkatedegseqkipeatnrrvwelskansrfat
    tfyqhladskndndniflsplsistafamtklgacndtlqqlmevfkfdtisektsdqih
    fffaklncrlyrkankssklvsanrlfgdksltfnetyqdiselvygaklqpldfkenae
    qsraainkwvsnktegritdvipseaineltvlvlvntiyfkglwkskfspentrkelfy
    kadgescsasmmyqegkfryrrvaegtqvlelpfkgdditmvlilpkpekslakvekelt
    pevlqewldeleemmlvvhmprfriedgfslkeqlqdmglvdlfspeksklpgivaegrd
    dlyvsdafhkaflevneegseaaastavviagrslnpnrvtfkanrpflvfirevplnti
    ifmgrvanpcvk
    

    Sequence, based on observed residues (ATOM records): (download)
    >1r1lL (L:)
    vdictakprdipmnpmciyeatnrrvwelskansrfattfyqhladskndndniflspls
    istafamtklgacndtlqqlmevfkfdtisektsdqihfffaklncrlyrkankssklvs
    anrlfgdksltfnetyqdiselvygaklqpldfkenaeqsraainkwvsnktegritdvi
    pseaineltvlvlvntiyfkglwkskfspentrkelfykadgescsasmmyqegkfryrr
    vaegtqvlelpfkgdditmvlilpkpekslakvekeltpevlqewldeleemmlvvhmpr
    friedgfslkeqlqdmglvdlfspeksklpgivaegrddlyvsdafhkaflevneegsea
    aastavviagrslnpnrvtfkanrpflvfirevplntiifmgrvanpcv