PDB entry 1qxp

View 1qxp on RCSB PDB site
Description: Crystal Structure of a mu-like calpain
Class: hydrolase chimera
Keywords: m-calpain, mu-calpain, catalytic triad, Ca(2+) requirement, HYDROLASE CHIMERA
Deposited on 2003-09-08, released 2004-02-03
The last revision prior to the SCOPe 2.03 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: 0.233
AEROSPACI score: 0.14 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: mu-like calpain
    Species: Rattus norvegicus [TaxId:10116]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q07009 (Start-48)
      • engineered (104)
      • cloning artifact (701)
      • cloning artifact (701)
      • cloning artifact (701)
      • cloning artifact (701)
      • cloning artifact (701)
      • cloning artifact (701)
      • expression tag (701)
    • Uniprot P97571 (49-636)
    • Uniprot Q07009 (637-701)
    • GB AAA64828 (716-899)
    Domains in SCOPe 2.03: d1qxpa1, d1qxpa2, d1qxpa3, d1qxpa4
  • Chain 'B':
    Compound: mu-like calpain
    Species: Rattus norvegicus [TaxId:10116]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q07009 (Start-48)
      • engineered (104)
      • cloning artifact (701)
      • cloning artifact (701)
      • cloning artifact (701)
      • cloning artifact (701)
      • cloning artifact (701)
      • cloning artifact (701)
      • expression tag (701)
    • Uniprot P97571 (49-636)
    • Uniprot Q07009 (637-701)
    • GB AAA64828 (716-899)
    Domains in SCOPe 2.03: d1qxpb1, d1qxpb2, d1qxpb3, d1qxpb4
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >1qxpA (A:)
    magiamklakdreaaeglgsheraikylnqdyetlrnecleagalfqdpafppvshslgf
    kelgpnssktygikwkrptellsnpqfivdgatrtdicqgalgdswllaaiasltlneti
    lhrvvpygqsfqegyagifhfqlwqfgewvdvvvddllptkdgklvfvhsaqgnefwsal
    lekayakvngsyealsggctseafedftggvtewydlqkapsdlyqiilkalergsllgc
    sinisdirdleaitfknlvrghaysvtdakqvtyqgqrvnlirmrnpwgevewkgpwsdn
    syewnkvdpyereqlrvkmedgefwmsfrdfireftkleicnltpdalksrtlrnwnttf
    yegtwrrgstaggcrnypatfwvnpqfkirleevddaddydsresgcsfllalmqkhrrr
    errfgrdmetigfavyqvprelagqpvhlkrdfflanasraqsehfinlrevsnrirlpp
    geyivvpstfepnkegdfllrffsekkagtqelddqiqanlpdekvlseeeiddnfktlf
    sklagddmeisvkelqtilnriiskhkdlrtngfslescrsmvnlmdrdgngklglvefn
    ilwnrirnyltifrkfdldksgsmsayemrmaieaagfklpcqlhqvivarfaddeliid
    fdnfvrclvrleilfkifkqldpentgtiqldliswlsfsvlgklaaaiehhhhhhmhys
    nieaneseeerqfrklfvqlagddmevsatelmnilnkvvtrhpdlktdgfgidtcrsmv
    avmdsdttgklgfeefkylwnnikkwqgiykrfetdrsgtigsnelpgafeaagfhlnqh
    iysmiirrysdetgnmdfdnfisclvrldamfrafrsldkngtgqiqvniqewlqltmys
    

    Sequence, based on observed residues (ATOM records): (download)
    >1qxpA (A:)
    agiamklakdreaaeglgsheraikylnqdyetlrnecleagalfqdpafppvshslgfk
    elgpnssktygikwkrptellsnpqfivdgatrtdicqgalgdswllaaiasltlnetil
    hrvvpygqsfqegyagifhfqlwqfgewvdvvvddllptkdgklvfvhsaqgnefwsall
    ekayakvngsyealsggctseafedftggvtewydlqkapsdlyqiilkalergsllgcs
    initfknlhaysvtdakqvtyqgqrvnlirmrnpwgevewkgpwsnsyewnkvdpyereq
    lrvkmedgefwmsfrdfireftkleicnltplksrtlrnwnttfyegtwrrgstaggcrn
    ypatfwvnpqfkirleevddsresgcsfllalmqkdmetigfavyqvprelvhlkrdffl
    anasraqsehfinlrevsnrirlppgeyivvpstfepnkegdfllrffsekkagtqeldd
    qiqanlpsklagddmeisvkelqtilnrtngfslescrsmvnlmdrngklglvefnilwn
    rirnyltifrkfdldksgsmsayemrmaieaagfklpcqlhqvivarfaddeliidfdnf
    vrclvrleilfkifkqldpentgtiqldliswlsfsvlmhysnifvqlagddmevsatel
    mnilnkhpdlkgfgidtcrsmvavmdsdttgklgfeefkylwnnikkwqgiytdrsgpga
    feaagfhlnqhiysetgnmdfdnfisclvrldamfrafrsldkngtgqiqvniqewlqlt
    mys
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >1qxpB (B:)
    magiamklakdreaaeglgsheraikylnqdyetlrnecleagalfqdpafppvshslgf
    kelgpnssktygikwkrptellsnpqfivdgatrtdicqgalgdswllaaiasltlneti
    lhrvvpygqsfqegyagifhfqlwqfgewvdvvvddllptkdgklvfvhsaqgnefwsal
    lekayakvngsyealsggctseafedftggvtewydlqkapsdlyqiilkalergsllgc
    sinisdirdleaitfknlvrghaysvtdakqvtyqgqrvnlirmrnpwgevewkgpwsdn
    syewnkvdpyereqlrvkmedgefwmsfrdfireftkleicnltpdalksrtlrnwnttf
    yegtwrrgstaggcrnypatfwvnpqfkirleevddaddydsresgcsfllalmqkhrrr
    errfgrdmetigfavyqvprelagqpvhlkrdfflanasraqsehfinlrevsnrirlpp
    geyivvpstfepnkegdfllrffsekkagtqelddqiqanlpdekvlseeeiddnfktlf
    sklagddmeisvkelqtilnriiskhkdlrtngfslescrsmvnlmdrdgngklglvefn
    ilwnrirnyltifrkfdldksgsmsayemrmaieaagfklpcqlhqvivarfaddeliid
    fdnfvrclvrleilfkifkqldpentgtiqldliswlsfsvlgklaaaiehhhhhhmhys
    nieaneseeerqfrklfvqlagddmevsatelmnilnkvvtrhpdlktdgfgidtcrsmv
    avmdsdttgklgfeefkylwnnikkwqgiykrfetdrsgtigsnelpgafeaagfhlnqh
    iysmiirrysdetgnmdfdnfisclvrldamfrafrsldkngtgqiqvniqewlqltmys
    

    Sequence, based on observed residues (ATOM records): (download)
    >1qxpB (B:)
    agiamklakdreaaeglgsheraikylnqdyetlrnecleagalfqdpafppvshslgfk
    elgpnssktygikwkrptellsnpqfivdgatrtdicqgalgdswllaaiasltlnetil
    hrvvpygqsfqegyagifhfqlwqfgewvdvvvddllptkdgklvfvhsaqgnefwsall
    ekayakvngsyealsggctseafedftggvtewydlqkapsdlyqiilkalergsllgcs
    inknlvghaysvtdakqvtyqgqrvnlirmrnpwgevewkgpwsewndpyereqlrvkme
    dgefwmsfrdfireftkleicnltpdalksrrnwnttfyegtwrrgstaggcrnypatfw
    vnpqfkirleevddaddydsresgcsfllalmqkhrfgrdmetigfavyqvprelagpvh
    lkrdfflanasraqsehfinlrevsnrirlppgeyivvpstfepnkegdfllrffsekka
    gtqelddqiqanlpdekvktlfisvkelqtilnrtngfslescrsmvnlmdlglvefnil
    wnrirnyltifrkfdldksgsmsayemrmaieaagfklpcqlhqvivarfaddeliidfd
    nfvrclvrleilfkifkqldpentgtiqldliswlsfsvlmhysnneseerqfrklfvql
    mevsatelmfgidtcrsmvavmdsdttgklgfeefkylwnnikkwqgirfetdrsgpgaf
    eaagfhlnqhiysmiirsdetgnmdfdnfisclvrldamfrafrsldkngtgqiqvniqe
    wlqltmys