PDB entry 1qwh
View 1qwh on RCSB PDB site
Description: a covalent dimer of transthyretin that affects the amyloid pathway
Class: hormone/growth factor
Keywords: thyroid hormone, liver, plasma, cerebrospinal fluid, polyneuropathy, disease mutation, transport, thyroxine, binding protein, HORMONE-GROWTH FACTOR COMPLEX
Deposited on
2003-09-02, released
2004-09-14
The last revision prior to the SCOPe 2.06 freeze date was dated
2011-07-13, with a file datestamp of
2011-05-08.
Experiment type: XRAY
Resolution: 1.36 Å
R-factor: 0.216
AEROSPACI score: 0.68
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Transthyretin
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.06: d1qwha_ - Chain 'B':
Compound: Transthyretin
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.06: d1qwhb_ - Heterogens: HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>1qwhA (A:)
plmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhgltteeefvegiyk
veidtksywkalgispfhehaevvftandsgprrytiaallspysysttavvtnpke
Sequence, based on observed residues (ATOM records): (download)
>1qwhA (A:)
plmvkvldavrgspainvavhvfrkadtwepfasgktsesgelhgltteefvegiykvei
dtksywkalgispfhehaevvftandsgprrytiaallspysysttavvt
- Chain 'B':
Sequence, based on SEQRES records: (download)
>1qwhB (B:)
plmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhgltteeefvegiyk
veidtksywkalgispfhehaevvftandsgprrytiaallspysysttavvtnpke
Sequence, based on observed residues (ATOM records): (download)
>1qwhB (B:)
plmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhglttefvegiykve
idtksywkalgispfhehaevvftanrytiaallspysysttavvt