PDB entry 1qwh

View 1qwh on RCSB PDB site
Description: a covalent dimer of transthyretin that affects the amyloid pathway
Class: hormone/growth factor
Keywords: thyroid hormone, liver, plasma, cerebrospinal fluid, polyneuropathy, disease mutation, transport, thyroxine, binding protein, HORMONE-GROWTH FACTOR COMPLEX
Deposited on 2003-09-02, released 2004-09-14
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 1.36 Å
R-factor: 0.216
AEROSPACI score: 0.68 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Transthyretin
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1qwha_
  • Chain 'B':
    Compound: Transthyretin
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1qwhb_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >1qwhA (A:)
    plmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhgltteeefvegiyk
    veidtksywkalgispfhehaevvftandsgprrytiaallspysysttavvtnpke
    

    Sequence, based on observed residues (ATOM records): (download)
    >1qwhA (A:)
    plmvkvldavrgspainvavhvfrkadtwepfasgktsesgelhgltteefvegiykvei
    dtksywkalgispfhehaevvftandsgprrytiaallspysysttavvt
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >1qwhB (B:)
    plmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhgltteeefvegiyk
    veidtksywkalgispfhehaevvftandsgprrytiaallspysysttavvtnpke
    

    Sequence, based on observed residues (ATOM records): (download)
    >1qwhB (B:)
    plmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhglttefvegiykve
    idtksywkalgispfhehaevvftanrytiaallspysysttavvt