PDB entry 1qvy

View 1qvy on RCSB PDB site
Description: Crystal structure of RhoGDI K(199,200)R double mutant
Class: signaling protein inhibitor
Keywords: protein crystallization; rational surface mutagenesis; RhoGDI; high resolution; X-ray diffraction
Deposited on 2003-08-29, released 2004-02-10
The last revision prior to the SCOP 1.73 freeze date was dated 2004-02-10, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 1.6 Å
R-factor: 0.173
AEROSPACI score: 0.59 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: rho GDP-dissociation inhibitor 1
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed):
    • Uniprot P52565 (1-138)
      • engineered (133-134)
    Domains in SCOP 1.73: d1qvya_
  • Chain 'B':
    Compound: rho GDP-dissociation inhibitor 1
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed):
    • Uniprot P52565 (1-138)
      • engineered (133-134)
    Domains in SCOP 1.73: d1qvyb_
  • Chain 'C':
    Compound: rho GDP-dissociation inhibitor 1
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed):
    • Uniprot P52565 (1-138)
      • engineered (133-134)
    Domains in SCOP 1.73: d1qvyc_
  • Chain 'D':
    Compound: rho GDP-dissociation inhibitor 1
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed):
    • Uniprot P52565 (1-138)
      • engineered (133-134)
    Domains in SCOP 1.73: d1qvyd_
  • Heterogens: SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1qvyA (A:)
mvpnvvvtgltlvcssapgpleldltgdlesfkkqsfvlkegveyrikisfrvnreivsg
mkyiqhtyrkgvkidktdymvgsygpraeeyefltpveeapkgmlargsysiksrftddd
ktdhlswewnltirrdwkd

    Sequence, based on observed residues (ATOM records): (download) 
    >1qvyA (A:)
vpnvvvtgltlvcssapgpleldltgdlesfkkqsfvlkegveyrikisfrvnreivsgm
kyiqhtyrkgvkidktdymvgsygpraeeyefltpveeapkgmlargsysiksrftdddk
tdhlswewnltirrdwkd

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1qvyB (B:)
mvpnvvvtgltlvcssapgpleldltgdlesfkkqsfvlkegveyrikisfrvnreivsg
mkyiqhtyrkgvkidktdymvgsygpraeeyefltpveeapkgmlargsysiksrftddd
ktdhlswewnltirrdwkd

    Sequence, based on observed residues (ATOM records): (download) 
    >1qvyB (B:)
vpnvvvtgltlvcssapgpleldltgdlesfkkqsfvlkegveyrikisfrvnreivsgm
kyiqhtyrkgvkidktdymvgsygpraeeyefltpveeapkgmlargsysiksrftdddk
tdhlswewnltirrdwkd

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1qvyC (C:)
mvpnvvvtgltlvcssapgpleldltgdlesfkkqsfvlkegveyrikisfrvnreivsg
mkyiqhtyrkgvkidktdymvgsygpraeeyefltpveeapkgmlargsysiksrftddd
ktdhlswewnltirrdwkd

    Sequence, based on observed residues (ATOM records): (download) 
    >1qvyC (C:)
vpnvvvtgltlvcssapgpleldltgdlesfkkqsfvlkegveyrikisfrvnreivsgm
kyiqhtyrkgvkidktdymvgsygpraeeyefltpveeapkgmlargsysiksrftdddk
tdhlswewnltirrdwkd

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1qvyD (D:)
mvpnvvvtgltlvcssapgpleldltgdlesfkkqsfvlkegveyrikisfrvnreivsg
mkyiqhtyrkgvkidktdymvgsygpraeeyefltpveeapkgmlargsysiksrftddd
ktdhlswewnltirrdwkd

    Sequence, based on observed residues (ATOM records): (download) 
    >1qvyD (D:)
vpnvvvtgltlvcssapgpleldltgdlesfkkqsfvlkegveyrikisfrvnreivsgm
kyiqhtyrkgvkidktdymvgsygpraeeyefltpveeapkgmlargsysiksrftdddk
tdhlswewnltirrdwkd