PDB entry 1qvu

View 1qvu on RCSB PDB site
Description: Crystal structure of the multidrug binding transcriptional repressor QacR bound to two drugs: ethidium and proflavine
Class: transcription
Keywords: QacR, multidrug binding protein, transcription, repressor, cooperative DNA binding
Deposited on 2003-08-28, released 2004-08-03
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.96 Å
R-factor: 0.223
AEROSPACI score: 0.22 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Transcriptional regulator qacR
    Species: Staphylococcus aureus [TaxId:1280]
    Gene: QACR OR SAVP031
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A0N4
      • conflict (140)
    Domains in SCOPe 2.08: d1qvua1, d1qvua2
  • Chain 'B':
    Compound: Transcriptional regulator qacR
    Species: Staphylococcus aureus [TaxId:1280]
    Gene: QACR OR SAVP031
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A0N4
      • conflict (140)
    Domains in SCOPe 2.08: d1qvub1, d1qvub2
  • Chain 'D':
    Compound: Transcriptional regulator qacR
    Species: Staphylococcus aureus [TaxId:1280]
    Gene: QACR OR SAVP031
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A0N4
      • conflict (140)
    Domains in SCOPe 2.08: d1qvud1, d1qvud2
  • Chain 'E':
    Compound: Transcriptional regulator qacR
    Species: Staphylococcus aureus [TaxId:1280]
    Gene: QACR OR SAVP031
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A0N4
      • conflict (140)
    Domains in SCOPe 2.08: d1qvue1, d1qvue2
  • Heterogens: ET, PRL

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1qvuA (A:)
mnlkdkilgvakelfikngynatttgeivklsesskgnlyyhfktkenlfleilnieesk
wqeqwkkeqikcktnrekfylynelsltteyyyplqnaiiefyteyyktnsinekmnkle
nkyidayhvifkegnlngewsindvnavskiaanavngivtftheqnineriklmnkfsq
iflnglskhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >1qvuA (A:)
nlkdkilgvakelfikngynatttgeivklsesskgnlyyhfktkenlfleilnieeskw
qeqwkkeqikcktnrekfylynelsltteyyyplqnaiiefyteyyktnsinekmnklen
kyidayhvifkegnlngewsindvnavskiaanavngivtftheqnineriklmnkfsqi
flngls

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1qvuB (B:)
mnlkdkilgvakelfikngynatttgeivklsesskgnlyyhfktkenlfleilnieesk
wqeqwkkeqikcktnrekfylynelsltteyyyplqnaiiefyteyyktnsinekmnkle
nkyidayhvifkegnlngewsindvnavskiaanavngivtftheqnineriklmnkfsq
iflnglskhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >1qvuB (B:)
nlkdkilgvakelfikngynatttgeivklsesskgnlyyhfktkenlfleilnieeskw
qeqwkkeqikcktnrekfylynelsltteyyyplqnaiiefyteyyktnsinekmnklen
kyidayhvifkegnlngewsindvnavskiaanavngivtftheqnineriklmnkfsqi
flngls

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1qvuD (D:)
mnlkdkilgvakelfikngynatttgeivklsesskgnlyyhfktkenlfleilnieesk
wqeqwkkeqikcktnrekfylynelsltteyyyplqnaiiefyteyyktnsinekmnkle
nkyidayhvifkegnlngewsindvnavskiaanavngivtftheqnineriklmnkfsq
iflnglskhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >1qvuD (D:)
nlkdkilgvakelfikngynatttgeivklsesskgnlyyhfktkenlfleilnieeskw
qeqwkkeqikcktnrekfylynelsltteyyyplqnaiiefyteyyktnsinekmnklen
kyidayhvifkegnlngewsindvnavskiaanavngivtftheqnineriklmnkfsqi
flngls

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >1qvuE (E:)
mnlkdkilgvakelfikngynatttgeivklsesskgnlyyhfktkenlfleilnieesk
wqeqwkkeqikcktnrekfylynelsltteyyyplqnaiiefyteyyktnsinekmnkle
nkyidayhvifkegnlngewsindvnavskiaanavngivtftheqnineriklmnkfsq
iflnglskhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >1qvuE (E:)
nlkdkilgvakelfikngynatttgeivklsesskgnlyyhfktkenlfleilnieeskw
qeqwkkeqikcktnrekfylynelsltteyyyplqnaiiefyteyyktnsinekmnklen
kyidayhvifkegnlngewsindvnavskiaanavngivtftheqnineriklmnkfsqi
flngls