PDB entry 1qvn

View 1qvn on RCSB PDB site
Description: Structure of SP4160 Bound to IL-2 V69A
Class: cytokine
Keywords: IL-2 Small Molecule hot spot, CYTOKINE
Deposited on 2003-08-28, released 2005-04-05
The last revision prior to the SCOPe 2.08 freeze date was dated 2013-01-09, with a file datestamp of 2013-01-04.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: 0.261
AEROSPACI score: 0.23 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: interleukin-2
    Species: Homo sapiens [TaxId:9606]
    Gene: IL2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P60568 (Start-131)
      • engineered (68)
    Domains in SCOPe 2.08: d1qvna_
  • Chain 'B':
    Compound: interleukin-2
    Species: Homo sapiens [TaxId:9606]
    Gene: IL2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P60568 (Start-131)
      • engineered (68)
    Domains in SCOPe 2.08: d1qvnb_
  • Chain 'C':
    Compound: interleukin-2
    Species: Homo sapiens [TaxId:9606]
    Gene: IL2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P60568 (Start-131)
      • engineered (68)
    Domains in SCOPe 2.08: d1qvnc_
  • Chain 'D':
    Compound: interleukin-2
    Species: Homo sapiens [TaxId:9606]
    Gene: IL2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P60568 (Start-131)
      • engineered (68)
    Domains in SCOPe 2.08: d1qvnd_
  • Heterogens: ZN, FRI

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1qvnA (A:)
aptssstkktqlqlehllldlqmilnginnyknpkltrmltfkfympkkatelkhlqcle
eelkpleealnlaqsknfhlrprdlisninvivlelkgsettfmceyadetativeflnr
witfcqsiistl

    Sequence, based on observed residues (ATOM records): (download) 
    >1qvnA (A:)
ssstkktqlqlehllldlqmilnginnyknpkltrmltfkfympkkatelkhlqcleeel
kpleealnlaqrprdlisninvivlelkgsettfmceyadetativeflnrwitfcqsii
stl

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1qvnB (B:)
aptssstkktqlqlehllldlqmilnginnyknpkltrmltfkfympkkatelkhlqcle
eelkpleealnlaqsknfhlrprdlisninvivlelkgsettfmceyadetativeflnr
witfcqsiistl

    Sequence, based on observed residues (ATOM records): (download) 
    >1qvnB (B:)
ssstkktqlqlehllldlqmilnginnyknpkltrmltfkfympkkatelkhlqcleeel
kpleealnlaqrprdlisninvivlelkgettfmceyadetativeflnrwitfcqsiis
tl

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1qvnC (C:)
aptssstkktqlqlehllldlqmilnginnyknpkltrmltfkfympkkatelkhlqcle
eelkpleealnlaqsknfhlrprdlisninvivlelkgsettfmceyadetativeflnr
witfcqsiistl

    Sequence, based on observed residues (ATOM records): (download) 
    >1qvnC (C:)
ssstkktqlqlehllldlqmilnginnyknpkltrmltfkfympkkatelkhlqcleeel
kpleealnlaqrprdlisninvivlelkgettfmceyadetativeflnrwitfcqsiis
tl

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1qvnD (D:)
aptssstkktqlqlehllldlqmilnginnyknpkltrmltfkfympkkatelkhlqcle
eelkpleealnlaqsknfhlrprdlisninvivlelkgsettfmceyadetativeflnr
witfcqsiistl

    Sequence, based on observed residues (ATOM records): (download) 
    >1qvnD (D:)
ssstkktqlqlehllldlqmilnginnyknpkltrmltfkfympkkatelkhlqcleeel
kpleealnlaqrprdlisninvivlelkgsettfmceyadetativeflnrwitfcqsii
stl